Results 101 to 110 of about 4,743,433 (368)

Equi‐MOI ratio for rapid baculovirus‐mediated multiprotein co‐expression in insect cells integrating selenomethionine for structural studies

FEBS Open Bio, EarlyView.
This study presents a versatile protocol for producing selenomethionine‐labeled multiprotein complexes, addressing challenges in structural biology such as experimental phasing in X‐ray crystallography. Its efficiency and adaptability make it valuable for researchers studying de novo, dynamic, or complex protein structures, promoting advancements in ...
Andrej Bitala, Mário Benko, Marek Nemčovič, Ivana Nemčovičová   +3 more
wiley   +1 more source

Does Cooking Technology Matter? Fuelwood Use and Efficiency of Different Cooking Technologies in Lilongwe District, Malawi [PDF]

Biomass, mainly firewood and charcoal contributes over 90% of Malawi’s total energy demand. As a result, deforestation is increasing at unprecedented rate and firewood is becoming scarce.
Maganga, Assa, Malakini, Memory
core   +1 more source

Memory

, 2014
According to Paul Zumthor, the Middle Ages occupies a specific position in our collective memory since this period provides the most obvious term of comparison for readers from the end of the twentieth century and the early twenty-first century. Modern medievalism grew in Europe and the United States precisely at this time, when western societies began
openaire   +3 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Clinical application of plasma P-tau217 to assess eligibility for amyloid-lowering immunotherapy in memory clinic patients with early Alzheimer’s disease

Alzheimer’s Research & Therapy
Background With the approval of disease-modifying treatments (DMTs) for early Alzheimer’s disease (AD), there is an increased need for efficient and non-invasive detection methods for cerebral amyloid-β (Aβ) pathology. Current methods, including positron
Matthew D. Howe, Karysa J. Britton, Hannah E. Joyce, William Menard, Sheina Emrani, Zachary J. Kunicki, Melanie A. Faust, Brittany C. Dawson, Meghan C. Riddle, Edward D. Huey, Shorena Janelidze, Oskar Hansson, Stephen P. Salloway   +12 more
doaj   +1 more source

DC-shifts in amplitude in-field generated by an oscillatory interference model of grid cell firing

Frontiers in Systems Neuroscience, 2014
Oscillatory interference models propose a mechanism by which the spatial firing pattern of grid cells can arise from the interaction of multiple oscillators that shift in relative phase. These models produce aspects of the physiological data such as the
Angela Christine Elizabeth Onslow, Michael E Hasselmo, Ehren Lee Newman   +2 more
doaj   +1 more source

Protecting Memory-Performance Critical Sections in Soft Real-Time Applications [PDF]

arXiv, 2015
Soft real-time applications such as multimedia applications often show bursty memory access patterns---regularly requiring a high memory bandwidth for a short duration of time. Such a period is often critical for timely data processing. Hence, we call it a memory-performance critical section.
arxiv  

CARAM: A Content-Aware Hybrid PCM/DRAM Main Memory System Framework [PDF]

arXiv, 2020
The emergence of Phase-Change Memory (PCM) provides opportunities for directly connecting persistent memory to main memory bus. While PCM achieves high read throughput and low standby power, the critical concerns are its poor write performance and limited durability, especially when compared to DRAM.
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Digital Light Processing of 2D Lattice Composites for Tunable Self‐Sensing and Mechanical Performance

Advanced Engineering Materials, EarlyView., 2023
The study presents the mechanical and in situ sensing performance of digital light processing‐enabled 2D lattice nanocomposites under monotonic tensile and repeated cyclic loading, and provides guidelines for the design of architectures suitable for strain sensors and smart lightweight structures.
Omar Waqas Saadi, Mohammed Ayaz Uddin, Andreas Schiffer, Shanmugam Kumar   +3 more
wiley   +1 more source