Results 81 to 90 of about 5,293,292 (333)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The age-related effect on cognitive performance in cognitively healthy elderly is mainly caused by underlying AD pathology or cerebrovascular lesions: implications for cutoffs regarding cognitive impairment

open access: yesAlzheimer’s Research & Therapy, 2020
Background As research in treatments for neurocognitive diseases progresses, there is an increasing need to identify cognitive decline in the earliest stages of disease for initiation of treatment in addition to determining the efficacy of treatment. For
Emma Borland   +4 more
doaj   +1 more source

Memory

open access: yes, 2014
According to Paul Zumthor, the Middle Ages occupies a specific position in our collective memory since this period provides the most obvious term of comparison for readers from the end of the twentieth century and the early twenty-first century. Modern medievalism grew in Europe and the United States precisely at this time, when western societies began
openaire   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Does Cooking Technology Matter? Fuelwood Use and Efficiency of Different Cooking Technologies in Lilongwe District, Malawi [PDF]

open access: yes
Biomass, mainly firewood and charcoal contributes over 90% of Malawi’s total energy demand. As a result, deforestation is increasing at unprecedented rate and firewood is becoming scarce.
Maganga, Assa, Malakini, Memory
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Review of Directed Self-Assembly Material, Processing, and Application in Advanced Lithography and Patterning

open access: yesMicromachines
Directed self-assembly (DSA) lithography, a cutting-edge technology based on the self-assembly of block copolymers (BCPs), has received significant attention in recent years.
Xiuyan Cheng   +7 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Clinical application of plasma P-tau217 to assess eligibility for amyloid-lowering immunotherapy in memory clinic patients with early Alzheimer’s disease

open access: yesAlzheimer’s Research & Therapy
Background With the approval of disease-modifying treatments (DMTs) for early Alzheimer’s disease (AD), there is an increased need for efficient and non-invasive detection methods for cerebral amyloid-β (Aβ) pathology. Current methods, including positron
Matthew D. Howe   +12 more
doaj   +1 more source

The RUB cage: Respiration-Ultrasonic vocalizations-Behavior acquisition set-up for assessing emotional memory in rats

open access: yesFrontiers in Behavioral Neuroscience, 2011
In animals, emotional memory is classically assessed through pavlovian fear conditioning in which a neutral novel stimulus (conditioned stimulus) is paired with an aversive unconditioned stimulus.
Chloe eHegoburu   +11 more
doaj   +1 more source

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