Results 61 to 70 of about 3,006,221 (300)
Nature Communications, 2020 Defects in DNA repair have been linked to brain aging and neurodegenerative disorders. Here the authors reveal a role for HDAC1 in stimulating OGG1 activity to alleviate 8-oxoG lesions with implications in the aging brain and neurodegenerative diseases.
Ping-Chieh Pao +17 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Memory, citizenship and social behaviour : Can we (really) learn from the past?
, 2015 Sarah Gensburger et Sandrine Lefranc (CNRS – ISP – Université Paris Ouest – ENS Cachan) In this research we seek to challenge the widespread belief that remembering our past is necessary for preserving peace and democracy and that we can “learn” from the
Women Memory
core
Recollection reduces unitised familiarity effect
, 2015 Two types of encoding tasks have been employed in previous research to investigate the beneficial effect of unitisation on familiarity-based associative recognition (unitised familiarity effect), namely the compound task and the interactive imagery task.
Shao, Hanyu +7 more
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Fostering Intra-University Collaborative Culture in Marginalised Institutions
Journal of Rural and Community DevelopmentCollaboration is essential for success in community-engaged research and development projects, particularly in academic institutions, where interdisciplinary practice is becoming more prevalent.
MEMORY MABIKA, Joseph Francis
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Word learning and verbal short-term memory: A computational account [PDF]
, 1996 Recent behavioral evidence suggests that human vocabulary acquisition processes and verbal short-term memory abilities may be ...
Prahlad Gupta, Gupta, Prahlad
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Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants
, 2011 Genetic studies in Drosophila have revealed two separable long-term memory pathways defined as anesthesia-resistant memory (ARM) and long-lasting long-term memory (LLTM).
Guan, Zhuo +7 more
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Rethinking sweet potato value chains in smallholder systems: A perspective from Zimbabwe
Jurnal Ilmiah PertanianSweet potato plays an important role in supporting food security, nutrition, and livelihoods in smallholder farming systems across sub-Saharan Africa. Despite its agronomic resilience and socio-economic potential, sweet potato often remains marginalised
Memory Mandaza, Emmanuel Mwakiwa
doaj +1 more source