Results 11 to 20 of about 5,300,714 (382)
Recruitment across two decades of NIH-funded Alzheimer’s disease clinical trials
Alzheimer’s Research & Therapy, 2023 Background Timely accrual of a representative sample is a key factor in whether Alzheimer’s disease (AD) clinical trials successfully answer the scientific questions under study.
Marina Ritchie +2 more
doaj +1 more source
Microglial APOE4: more is less and less is more
Molecular Neurodegeneration, 2023 Apolipoprotein E (APOE) is the single greatest genetic risk factor for late onset Alzheimer’s disease (AD). Yet, the cell-specific effects of APOE on microglia function have remained unclear.
Ghazaleh Eskandari-Sedighi +1 more
doaj +1 more source
Journal of Neuroinflammation, 2018 Background Brain inflammation including increases in inflammatory cytokines such as IL-1β is widely believed to contribute to the pathophysiology of Alzheimer’s disease.
Liqi Tong +2 more
doaj +1 more source
Prospective memory impairments in Alzheimer's Disease and behavioral variant frontotemporal dementia: Clinical and neural correlates [PDF]
, 2016 BACKGROUND: Prospective memory (PM) refers to a future-oriented form of memory in which the individual must remember to execute an intended action either at a future point in time (Time-based) or in response to a specific event (Event-based).
Addis +64 more
core +1 more source
Temporally Graded Activation of Neocortical Regions in Response to Memories of Different Ages [PDF]
, 2007 The temporally graded memory impairment seen in many neurobehavioral disorders implies different neuroanatomical pathways and/or cognitive mechanisms involved in storage and retrieval of memories of different ages.
Antuono, Piero +7 more
core +2 more sources
Rehabilitation of Memory Disorders
Clinical and Translational Neuroscience, 2023 Memory disorders are common in clinical practice. This review focuses on the rehabilitation of anterograde amnesia, the inability to learn and retrieve new information, in non-degenerative brain disease. Diverse mnemonic strategies may be helpful in learning specific pieces of information.
Schnider, Armin, Ptak, Radek
openaire +3 more sources
Alzheimer’s Research & Therapy, 2019 Background Alzheimer’s disease (AD) clinical trials require enrollment of a participant and a study partner, whose role includes assessing participant cognitive and functional performance.
Michelle M. Nuño +3 more
doaj +1 more source
Subjective experience of episodic memory and metacognition: a neurodevelopmental approach. [PDF]
, 2013 Episodic retrieval is characterized by the subjective experience of remembering. This experience enables the co-ordination of memory retrieval processes and can be acted on metacognitively.
Eustache, F +4 more
core +2 more sources
Blood pressure variability and plasma Alzheimer’s disease biomarkers in older adults
Scientific Reports, 2022 Blood pressure variability is an emerging risk factor for Alzheimer’s disease in older adults, independent of average blood pressure levels. Growing evidence suggests increased blood pressure variability is linked to Alzheimer’s disease pathophysiology ...
Isabel J. Sible +17 more
doaj +1 more source
Transcutaneous vagus nerve stimulation does not affect verbal memory performance in healthy volunteers [PDF]
, 2020 Introduction: Invasive vagus nerve stimulation (VNS) improves word recognition memory in patients with epilepsy. Recent studies with transcutaneous VNS (tVNS) have also shown positive effects on various subdomains of cognitive functioning in healthy ...
Boon, Paul +8 more
core +1 more source