Results 31 to 40 of about 3,905,908 (191)

Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease

Scientific Data, 2021
Measurement(s) Protein Expression • gene expression • electrophysiology data • protein measurement • behavior Technology Type(s) immunofluorescence microscopy assay • RNA sequencing • electrophysiology assay • Electrochemiluminescence Immunoassay ...
Stefania Forner, Shimako Kawauchi, Gabriela Balderrama-Gutierrez, Enikö A. Kramár, Dina P. Matheos, Jimmy Phan, Dominic I. Javonillo, Kristine M. Tran, Edna Hingco, Celia da Cunha, Narges Rezaie, Joshua A. Alcantara, David Baglietto-Vargas, Camden Jansen, Jonathan Neumann, Marcelo A. Wood, Grant R. MacGregor, Ali Mortazavi, Andrea J. Tenner, Frank M. LaFerla, Kim N. Green   +20 more
doaj   +1 more source

Using the yes/no recognition response pattern to detect memory malingering [PDF]

, 2013
Schindler S, Kißler J, Kühl K-P, Hellweg R, Bengner T. Using the yes/no recognition response pattern to detect memory malingering. BMC Psychology.
Hellweg, Rainer, Schindler, Sebastian ; https://orcid.org/, Bengner, Thomas, Kißler, Johanna, Kühl, Klaus-Peter   +4 more
core   +1 more source

Diminished time-based, but undiminished event-based, prospective memory among intellectually high-functioning adults with autism: Relation to working memory ability. [PDF]

, 2013
Objective: Prospective memory (PM) is the ability to remember to carry out an intended action. Working memory is the ability to store information in mind while processing potentially distracting information.
Lind, Sophie E, Lind, Sophie E., Grainger, C., Lind, S. E., Williams, David M., Grainger, Catherine, Lind, Sophie, Williams, David, Jarrold, Christopher, Jarrold, C., Williams, D. M., Williams, David M   +11 more
core   +1 more source

Targeted Control of Gene Expression Using CRISPR-Associated Endoribonucleases

Cells
CRISPR-associated endoribonucleases (Cas RNases) cleave single-stranded RNA in a highly sequence-specific manner by recognizing and binding to short RNA sequences known as direct repeats (DRs).
Sagar J. Parikh, Heather M. Terron, Luke A. Burgard, Derek S. Maranan, Dylan D. Butler, Abigail Wiseman, Frank M. LaFerla, Shelley Lane, Malcolm A. Leissring   +8 more
doaj   +1 more source

5′ DREDGE: Direct Repeat-Enabled Downregulation of Gene Expression via the 5′ UTR of Target Genes

Cells
Despite the availability of numerous methods for controlling gene expression, there remains a strong need for technologies that maximize two key properties: selectivity and reversibility.
Sagar J. Parikh, Heather M. Terron, Luke A. Burgard, Dylan D. Butler, Frank M. LaFerla, Shelley Lane, Malcolm A. Leissring   +6 more
doaj   +1 more source

Communicating mild cognitive impairment diagnoses with and without amyloid imaging

Alzheimer’s Research & Therapy, 2017
Background Mild cognitive impairment (MCI) has an uncertain etiology and prognosis and may be challenging for clinicians to discuss with patients and families.
Joshua D. Grill, Liana G. Apostolova, Szofia Bullain, Jeffrey M. Burns, Chelsea G. Cox, Malcolm Dick, Dean Hartley, Claudia Kawas, Sarah Kremen, Jennifer Lingler, Oscar L. Lopez, Mark Mapstone, Aimee Pierce, Gil Rabinovici, J. Scott Roberts, Seyed Ahmad Sajjadi, Edmond Teng, Jason Karlawish   +17 more
doaj   +1 more source

Medial Temporal Lobe Contributions to Future Thinking: Evidence from Neuroimaging and Amnesia

Psychologica Belgica, 2012
Following early amnesic case reports, there is now considerable evidence suggesting a link between remembering the past and envisioning the future. This link is evident in the overlap in neural substrates as well as cognitive processes involved in both ...
Mieke Verfaellie, Elizabeth Race, Margaret M Keane   +2 more
doaj   +1 more source

Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue

STAR Protocols, 2022
Summary: Single-nucleus ATAC sequencing (snATAC-seq) employs a hyperactive Tn5 transposase to gain precise information about the cis-regulatory elements in specific cell types. However, the standard protocol of snATAC-seq is not optimized for all tissues,
Zechuan Shi, Sudeshna Das, Samuel Morabito, Emily Miyoshi, Vivek Swarup   +4 more
doaj   +1 more source

PSYCHODIAGNOSTICS OF MEMORY DISORDERS

, 2022
The article focuses on the methods of psychodiagnostics methods used in the diagnosis of disorders of cognitive processes, especially memory disorders, and their necessity and importance, and is devoted to the analysis of empirical research on the ...
Melibaeva Ruzakhan Nasirovna
core   +1 more source

The Effect of Viewpoint Dependence in Spatial Memory Tasks on Intrusive Memories in Analogue Trauma [PDF]

, 2014
Part one of this thesis is a literature review on the use of Imagery Restructuring (IR) within anxiety disorders. Narrative methods were used to synthesise the findings of 18 studies.
Polack, RELR
core