Results 41 to 50 of about 948,328 (207)

Disorder-Induced Microscopic Magnetic Memory [PDF]

Physical Review Letters, 2005
Using coherent x-ray speckle metrology, we have measured the influence of disorder on major loop return point memory (RPM) and complementary point memory (CPM) for a series of perpendicular anisotropy Co/Pt multilayer films. In the low disorder limit, the domain structures show no memory with field cycling--no RPM and no CPM.
Pierce, M S, Buechler, C R, Sorensen, L B, Turner, J J, Kevan, S D, Jagla, E A, Deutsch, J M, Mai, T, Narayan, O, Davies, J E, Liu, K, Dunn, J Hunter, Chesnel, K M, Kortright, J B, Hellwig, O, Fullerton, E E   +15 more
openaire   +5 more sources

Neurocognitive profiles in autism spectrum disorder [PDF]

, 2014
textThe current research project examines the performance of a group of high functioning young adult males with autism spectrum disorders on standardized measures of neurocognitive functioning to determine whether distinct cognitive profiles of strengths
Wagner, Amanda E.
core  

From extinction learning to anxiety treatment: mind the gap [PDF]

, 2019
Laboratory models of extinction learning in animals and humans have the potential to illuminate methods for improving clinical treatment of fear-based clinical disorders.
Carpenter, Joseph K., Hofmann, Stefan G., Pinaire, Megan   +2 more
core   +1 more source

Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta

Neurobiology of Disease, 2010
Previously we showed that anti-Aβ peptide immunotherapy significantly attenuated Alzheimer's-like amyloid deposition in the central nervous system of aged canines.
Vitaly Vasilevko, Viorela Pop, Hyun Jin Kim, Tommy Saing, Charles C. Glabe, Saskia Milton, Edward G. Barrett, Carl W. Cotman, David H. Cribbs, Elizabeth Head   +9 more
doaj   +1 more source

Exercise counteracts declining hippocampal function in aging and Alzheimer's disease

Neurobiology of Disease, 2013
Alzheimer's disease (AD) afflicts more than 5.4 million Americans and ranks as the most common type of dementia (Thies and Bleiler, 2011), yet effective pharmacological treatments have not been identified.
Karlie A. Intlekofer, Carl W. Cotman
doaj   +1 more source

Education and Message Framing Increase Willingness to Undergo Research Lumbar Puncture: A Randomized Controlled Trial

Frontiers in Medicine, 2020
Reluctance to undergo lumbar puncture (LP) is a barrier to neurological disease biomarker research. We assessed whether an educational intervention increased willingness to consider research LP and whether message framing modified intervention ...
Megan G. Witbracht, Olivia M. Bernstein, Vanessa Lin, Christian R. Salazar, S. Ahmad Sajjadi, S. Ahmad Sajjadi, Dan Hoang, Chelsea G. Cox, Daniel L. Gillen, Daniel L. Gillen, Joshua D. Grill, Joshua D. Grill, Joshua D. Grill, Joshua D. Grill   +13 more
doaj   +1 more source

Neuropsychological Decline Stratifies Dementia Risk in Cognitively Unimpaired and Impaired Older Adults

Frontiers in Aging Neuroscience, 2022
ObjectiveValidation and widespread use of markers indicating decline in serial neuropsychological exams has remained elusive despite potential value in prognostic and treatment decision-making.
Jean K. Ho, Daniel A. Nation, Daniel A. Nation   +2 more
doaj   +1 more source

Effectiveness of a local recruitment registry in older adults in Southern California

BMC Medical Research Methodology
Background Despite their potential as tools for improving the efficiency of accrual in clinical research, few analyses have assessed the effectiveness of recruitment registries.
Adam I. Birnbaum, Adrijana Gombosev, Zion T. Grant-Freeman, Dan Hoang, Daniel L. Gillen, Joshua D. Grill   +5 more
doaj   +1 more source

Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition

Neurobiology of Disease, 2014
Recent studies on tauopathy animal models suggest that the concomitant expression of the endogenous murine tau delays the pathological accumulation of human tau, and interferes with the disease progression.
David Baglietto-Vargas, Masashi Kitazawa, Elaine J. Le, Tatiana Estrada-Hernandez, Carlos J. Rodriguez-Ortiz, Rodrigo Medeiros, Kim N. Green, Frank M. LaFerla   +7 more
doaj   +1 more source

Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40

Alzheimer’s Research & Therapy, 2020
Background Cathepsin D (CatD) is a lysosomal protease that degrades both the amyloid β-protein (Aβ) and the microtubule-associated protein, tau, and has been genetically linked to late-onset Alzheimer disease (AD).
Caitlin N. Suire, Samer O. Abdul-Hay, Tomoko Sahara, Dongcheul Kang, Monica K. Brizuela, Paul Saftig, Dennis W. Dickson, Terrone L. Rosenberry, Malcolm A. Leissring   +8 more
doaj   +1 more source