Results 71 to 80 of about 948,328 (207)

Transcriptional activation of USP16 gene expression by NFκB signaling

Molecular Brain, 2019
Ubiquitin Specific Peptidase 16 (USP16) has been reported to contribute to somatic stem-cell defects in Down syndrome. However, how this gene being regulated is largely unknown. To study the mechanism underlying USP16 gene expression, USP16 gene promoter
Shou Yang, Juelu Wang, Shipeng Guo, Daochao Huang, Isabel Bestard Lorigados, Xing Nie, Dandan Lou, Yanhua Li, Mingjing Liu, Yu Kang, Weihui Zhou, Weihong Song   +11 more
doaj   +1 more source

The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders [PDF]

, 2013
Understanding the neurochemical basis for cognitive function is one of the major goals of neuroscience, with a potential impact on the diagnosis, prevention and treatment of a range of psychiatric and neurological disorders.
Akagbosu, Akladios, Alexander, Alkondon, Alkondon, Alkondon, Amori, Andersen, Atlas, Autier, Backman, Beal, Benatti, Bonda, Breese, Carpenedo, Carpenedo, Casazza, Castellano, Ceresoli-Borroni, Cesura, Chess, Chess, Chess, Chiarugi, Chiarugi, Clark, Cochran, Cozzi, Cui, Daily, Dalley, Dantzer, Darlington, Darlington, Davidson, Deiana, Della Torre, DiNatale, Dobelis, Dounay, Eastman, Erhardt, Forrest, Forrest, Forrest, Forrest, Fukui, Gellert, Giordani, Giorgini, Gold, Graef, Guidetti, Guidetti, Guidetti, Guidetti, Guillemin, Guillemin, Hardingham, Hedges, Henderson, Heng, Hernandez, Heyes, Hilmas, Holtze, Jason, Jauch, Jentsch, Jurgens, Kalisch, Kandanearatchi, Kiank, Kihara, Kloet, Kocki, Konradsson-Geuken, Lawrence, Lawrence, Linderholm, Lindsley, Luchowski, Luchowski, Lupien, Marin, Mexal, Millan, Miller, Minzenberg, Miura, Moeller, Mok, Muchowski, Muchowski, Mueller, Muscatell, Myint, Nagy, Neill, Newcomer, Newcomer, Nilsson, Nilsson, Nozaki, O'Connor, Olsson, Onur, Owe-Young, Paterson, Pearson, Pechtel, Pellicciari, Pellicciari, Perkins, Pertovaara, Pevarello, Phillips, Pocivavsek, Pocivavsek, Popoli, Popoli, Potter, Rahman, Raison, Rassoulpour, Ren, Robert, Rodgers, Rossi, Ryu, Röver, Saito, Salazar, Sapko, Sarter, Sathyasaikumar, Sathyasaikumar, Schwarcz, Schwarcz, Schwarcz, Schwarcz, Shear, Speciale, Speciale, Stazka, Stazka, Stone, Stone, Stone, Stone, Stone, Stoy, Tadaiesky, Tatter, Teichberg, Teichberg, Ting, Trecartin, Tse, Varasi, Vezzani, Walker, Wang, Wang, Wejksza, Wejksza, Wonodi, Xu, Yamada, Yuen, Zisapel, Zmarowski   +172 more
core   +1 more source

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

Neurobiology of Disease, 2014
Synapse number is the best indicator of cognitive impairment In Alzheimer's disease (AD), yet the respective contributions of Aβ and tau, particularly human wild-type tau, to synapse loss remain undefined.
Meredith A. Chabrier, David Cheng, Nicholas A. Castello, Kim N. Green, Frank M. LaFerla   +4 more
doaj   +1 more source

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population [PDF]

, 2015
Acknowledgements Generation Scotland has received core funding from the Chief Scientist Office of the Scottish Government Health Directorates CZD/16/6 and the Scottish Funding Council HR03006.
Clarke, T. K., Cox, S., Davies, G., Deary, I. J., Fernandez-Pujals, A. M., Hall, L. S., Hansell, N. K., Hayward, C., Hocking, L. J., Liewald, D. C., Lupton, M. K., MacIntyre, D. J., Martin, N. G., McIntosh, A. M., Medland, S. E., Montgomery, G. W., Padmanabhan, S., Pattie, A., Porteous, D. J., Smith, B. H., Starr, J., Thomson, P. A., Wright, M. J.   +22 more
core   +6 more sources

High pulse wave velocity is associated with enlarged perivascular spaces in dementia with Lewy bodies

Scientific Reports
Previous studies have demonstrated associations between enlarged perivascular spaces (EPVS) and dementias such as Alzheimer’s disease. However, an association between EPVS and dementia with Lewy bodies (DLB) has not yet been clarified.
Naoki Saji, Yoshino Kinjo, Kenta Murotani, Shumpei Niida, Akinori Takeda, Takashi Sakurai   +5 more
doaj   +1 more source

Orthopaedic manual physical therapy for post-stroke shoulder pain: two case reports including clinical assessments and participants’ experiences

Journal of Rehabilitation Medicine - Clinical Communications
Objective: To descriptively evaluate Orthopaedic Manual Physical Therapy – a novel intervention for post-stroke shoulder pain – by use of clinical assessments and the participants’ experiences. Design: Two case reports.
Ingrid Lindgren, Arne G. Lindgren, Håkan Carlsson, Tobias Lundgren, Christina Brogårdh   +4 more
doaj   +1 more source

Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report. [PDF]

, 2019
Imaging of the living human brain is a powerful tool to probe the interactions between brain, gut and microbiome in health and in disorders of brain-gut interactions, in particular IBS.
Aziz, Qasim, Borsook, David, Elsenbruch, Sigrid, Kilpatrick, Lisa, Labus, Jennifer, Mayer, Emeran A, Schweinhardt, Petra, Tracey, Irene, Van Oudenhove, Lukas   +8 more
core   +2 more sources

Memory and anxiety disorders

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995
Experimental psychopathologists have identified varying patterns in memory bias in people with depressive and anxiety disorders. Individuals suffering from depression tend to exhibit explicit memory deficits for positively-valanced material, and sometimes exhibit biases for retrieving negative self-relevant information as well.
openaire   +3 more sources

Low-Frequency rTMS Ameliorates Autistic-Like Behaviors in Rats Induced by Neonatal Isolation Through Regulating the Synaptic GABA Transmission

Frontiers in Cellular Neuroscience, 2018
Patients with autism spectrum disorder (ASD) display abnormalities in neuronal development, synaptic function and neural circuits. The imbalance of excitatory and inhibitory (E/I) synaptic transmission has been proposed to cause the main behavioral ...
Tao Tan, Wei Wang, Haitao Xu, Zhilin Huang, Yu Tian Wang, Yu Tian Wang, Zhifang Dong   +6 more
doaj   +1 more source

Gender, Psychiatric and Cognitive Status Related to Experiential Auras in Patients with Temporal Lobe Epilepsy [PDF]

, 2018
Objective: To determine whether the experiential auras in patients with temporal lobe epilepsy (TLE) are related to gender, psychiatric comorbidity, material-specific memory impairment, lateralization by video-EEG and structural neuroimaging ...
Benjumea Cuartas, Vanessa, Giagante, Brenda, Kochen, Sara Silvia   +2 more
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