Results 51 to 60 of about 795,154 (263)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Environmental Research CommunicationsThe Western Tibetan Plateau (WTP) is a semi-arid area, yet its precipitation forms a critical component of the Asian Water Tower’s hydrological cycle. This study has revealed that precipitation anomalies in WTP exhibit a significant persistence from May ...
Haoxin Zhang, Hong-Li Ren, Mengmeng Lu
doaj +1 more source
Effects of Audiovisual Memory Cues on Working Memory Recall
Vision, 2021 Previous studies have focused on topics such as multimodal integration and object discrimination, but there is limited research on the effect of multimodal learning in memory.
Hilary C. Pearson +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
More Lies Lead to More Memory Impairments in Daily Life
Frontiers in Psychology, 2022 Previous studies have demonstrated that lying can undermine memory and that its memory-undermining effects could be modulated by the cognitive resources required to tell lies.
Yan Li +4 more
doaj +1 more source
Subsequent memory effects in schizophrenia [PDF]
Psychiatry Research: Neuroimaging, 2014 Differential neural activation at encoding can predict which stimuli will be subsequently remembered or forgotten, and memory deficits are pronounced in schizophrenia. We used event-related functional magnetic resonance imaging (fMRI) to investigate subsequent memory (SM) effects for visual fractals in patients with schizophrenia (n=26) and healthy ...
Azurii K, Collier +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Itô equation model for dispersion of solutes in heterogeneous media
Journal of Numerical Analysis and Approximation Theory, 2008 Transport processes in heterogeneous media such as ionized plasmas, natural porous media, and turbulent atmosphere are often modeled as diffusion processes in random velocity fields. Using the Itô formalism, we decompose the second spatial moments of the
N. Suciu +4 more
doaj +2 more sources
Memory effects in the electron glass [PDF]
EPL (Europhysics Letters), 2014 We investigate theoretically the slow non-exponential relaxation dynamics of the electron glass out of equilibrium, where a sudden change in carrier density reveals interesting memory effects. The self-consistent model of the dynamics of the occupation numbers in the system successfully recovers the general behavior found in experiments.
Meroz, Yasmine +2 more
openaire +2 more sources