Results 81 to 90 of about 2,605,266 (346)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Power Amplifier Predistortion Using Reduced Sampling Rates in the Forward and Feedback Paths
SensorsThe feasibility of implementing digital predistortion for next-generation wireless communication is faced with a dilemma due to the ever-increasing demand for faster data rates. This causes the utilized bandwidth to increase significantly, as seen in the
Serien Ahmed +3 more
doaj +1 more source
Subsequent memory effects in schizophrenia [PDF]
Psychiatry Research: Neuroimaging, 2014 Differential neural activation at encoding can predict which stimuli will be subsequently remembered or forgotten, and memory deficits are pronounced in schizophrenia. We used event-related functional magnetic resonance imaging (fMRI) to investigate subsequent memory (SM) effects for visual fractals in patients with schizophrenia (n=26) and healthy ...
Azurii K, Collier +4 more
openaire +2 more sources
Entanglement Scrambling in 2d Conformal Field Theory [PDF]
, 2015 We investigate how entanglement spreads in time-dependent states of a 1+1 dimensional conformal field theory (CFT). The results depend qualitatively on the value of the central charge.
Asplund, Curtis T. +3 more
core +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Robust effects of working memory demand during naturalistic language comprehension in language-selective cortex [PDF]
, 2021 Cory Shain
openalex +1 more source
Spacing effects in picture memory [PDF]
Memory & Cognition, 1973 Three experiments were conducted to capitalize on the conclusion of Shaffer and Shiffrin (1972) that complex visual scenes are not rehearsed in testing the hypothesis that the effect of spacing on memory is due to rehearsal. In Experiment I, a list of vacation slides was presented in which both the number of repetitions and the spacing of repetitions ...
D L, Hintzman, M K, Rogers
openaire +2 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Random sampling of long-memory stationary processe [PDF]
, 2008 This paper investigates the second order properties of a stationary process after random sampling. While a short memory process gives always rise to a short memory one, we prove that long-memory can disappear when the sampling law has heavy enough tails.
Philippe, Anne, Viano, Marie-Claude
core +2 more sources