Results 1 to 10 of about 326,886 (149)

Pridopidine Reverses Phencyclidine-Induced Memory Impairment [PDF]

open access: yesFrontiers in Pharmacology, 2018
Pridopidine is in clinical trials for Huntington's disease treatment. Originally developed as a dopamine D2 receptor (D2R) ligand, pridopidine displays about 100-fold higher affinity for the sigma-1 receptor (sigma-1R).
Kristoffer Sahlholm   +7 more
doaj   +6 more sources

The Associations between Polysomnographic Parameters and Memory Impairment among Patients with Obstructive Sleep Apnea: A 10-Year Hospital-Based Longitudinal Study

open access: yesBiomedicines, 2023
Obstructive sleep apnea (OSA) has been associated with cognitive decline via several mechanisms, including intermittent hypoxemia, sleep fragmentation, and neuroinflammation.
Wei-Chen Chien   +5 more
doaj   +1 more source

Transcriptome Profiles of IncRNA and mRNA Highlight the Role of Ferroptosis in Chronic Neuropathic Pain With Memory Impairment

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background: Chronic neuropathic pain is commonly associated with memory loss, which increases the risk of dementia, lowers life quality and spending.
Yidan Tang   +10 more
doaj   +1 more source

Memory rescue and learning in synaptic impaired neuronal circuits

open access: yesiScience, 2023
Summary: Neuronal impairment is a characteristic of Alzheimer’s disease (AD), but its effect on neural activity dynamics underlying memory deficits is unclear.
Kwan Tung Li, Daoyun Ji, Changsong Zhou
doaj   +1 more source

Misaligned feeding impairs memories [PDF]

open access: yeseLife, 2015
Robust sleep/wake rhythms are important for health and cognitive function. Unfortunately, many people are living in an environment where their circadian system is challenged by inappropriate meal- or work-times. Here we scheduled food access to the sleep time and examined the impact on learning and memory in mice. Under these conditions, we demonstrate
Dawn H Loh   +6 more
openaire   +5 more sources

Protective Effects of Dapsone on Scopolamine-Induced Memory Impairment in Mice: Involvement of Nitric Oxide Pathway

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2022
Introduction: The leading cause of memory impairment is dementia-related disorders. Since current treatments for memory impairment target the neuroinflammatory pathways, we selected dapsone, an anti-inflammatory agent, to evaluate its effects on ...
Nafise Noroozi   +7 more
doaj   +1 more source

Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation

open access: yesStem Cell Reports, 2020
Summary: Aberrant neuronal development and the persistence of mitotic cellular populations have been implicated in a multitude of neurological disorders, including Huntington's disease (HD).
Charlene Smith-Geater   +16 more
doaj   +1 more source

Rumination and Impaired Prospective Memory [PDF]

open access: yesThe Journal of General Psychology, 2018
Prospective memory (PM), remembering to remember, is crucial to everyday functioning. Understanding factors associated with PM impairments is thus important. One likely factor is rumination: a common cognitive process comprising repetitive self-focused thoughts.
Fredman Stein, Kim   +2 more
openaire   +3 more sources

Memory impairment in children with language impairment [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2010
Aim  The aim of this study was to assess whether any memory impairment co‐occuring with language impairment is global, affecting both verbal and visual domains, or domain specific.Method  Visual and verbal memory, learning, and processing speed were assessed in children aged 6 years to 16 years 11 months (mean 9y 9m, SD 2y 6mo) with current, resolved ...
Baird, Gillian   +3 more
openaire   +3 more sources

Sex Differences in Memory: Do Female Reproductive Factors Explain the Differences?

open access: yesFrontiers in Endocrinology, 2022
BackgroundThe sex differences in memory impairment were inconclusive, and the effect of female reproductive factors (age at menarche, age at menopause, and reproductive period) on the differences was not clear.
Jie Li   +10 more
doaj   +1 more source

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