Results 21 to 30 of about 327,005 (268)

Comparing methods for glomerular filtration rate estimation

Journal of Clinical and Translational Science
Background: The glomerular filtration rate (GFR), estimated from serum creatinine (SCr), is widely used in clinical practice for kidney function assessment, but SCr-based equations are limited by non-GFR determinants and may introduce inaccuracies across
Xiaoqian Zhu, Tariq Shafi, Keith C. Norris, Jeannette Simino, Srishti Shrestha, Thomas H. Mosley, Michael E. Griswold, Seth T. Lirette   +7 more
doaj   +1 more source

Sugar Kick Prevents Memory Impairment [PDF]

Journal of Medicinal Chemistry, 2019
Pathological hyperphosphorylation of tau and subsequent aggregation to form neurofibrillary tangles (NFTs) is closely related to progression of neurodegenerative diseases such as Alzheimer's disease (AD) and progressive supranuclear palsy. A recent study showed that MK-8719 (6) is a selective and potent small molecule inhibitor of human O-GlcNAcase ...
Santosh Rudrawar, Philip Ryan
openaire   +3 more sources

EBF1 is a potential biomarker for predicting progression from mild cognitive impairment to Alzheimer's disease: an in silico study

Frontiers in Aging Neuroscience
IntroductionThe prediction of progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) is an important clinical challenge. This study aimed to identify the independent risk factors and develop a nomogram model that can predict ...
Yanxiu Ju, Yanxiu Ju, Songtao Li, Songtao Li, Xiangyi Kong, Qing Zhao, Qing Zhao   +6 more
doaj   +1 more source

Low dose aspirin blocks breast cancer-induced cognitive impairment in mice.

PLoS ONE, 2018
Cancer patients with non-central nervous system tumors often suffer from cognitive impairment. While chemotherapy has long been attributed as the cause of these memory, learning and concentration difficulties, we recently observed cognitive impairment in
Adam K Walker, Aeson Chang, Alexandra I Ziegler, Haryana M Dhillon, Janette L Vardy, Erica K Sloan   +5 more
doaj   +1 more source

Outcomes of peripherally inserted central catheter vs conventional central venous catheters in hematological cancer patients: a systematic review and meta-analysis

Hematology
Objective This review aimed to examine if there is any difference in the risk of thrombosis and central line-associated bloodstream infection (CLABSI) with the use of peripherally inserted central catheter (PICC) and conventional central venous catheters
Weilei Ge, Chen Zheng
doaj   +1 more source

Subjective memory disorders and psychological distress in post COVID 19

European Psychiatry, 2023
Introduction In addition to psychological distress in patients with COVID 19, neurological and neurocognitive manifestations, such as memory impairment, are increasingly reported. Screening for cognitive impairment is therefore crucial.
N. Halouani, D. Gdoura, O. Bouattour, A. Chamseddine, N. Moussa, S. Ellouze, J. Aloulou   +6 more
doaj   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata, Keita Ueda, Tsukasa Ueno, Katsutsugu Umeda, Kentaro Ueno, Kanade Tanaka, Noyuri Nishida, Rie Yamawaki, Megumi Nukui, Yoshiki Arakawa   +9 more
wiley   +1 more source

Severity of memory impairment in the elderly: Association with health care resource use and functional limitations in the United States

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2017
Introduction Dementia is a prevalent condition in older adults associated with decline in cognitive and functional abilities and substantial burden.
Myrlene Sanon Aigbogun, Robert Stellhorn, Holly Krasa, Dusan Kostic   +3 more
doaj   +1 more source

Working Memory, Rumination, and Autobiographical Memory Specificity Impairment [PDF]

Iranian Rehabilitation Journal, 2023
Objectives: Specificity impairment is a memory alteration that occurs in people with major depressive disorder (MDD). In this investigation, we intended to shine a light on obscure aspects of executive resource and capture and rumination frameworks to ...
Pouria Rahgosha, Pezhman Hadinezhad, Seyed Hamzeh Hosseini, Ehsan Abedini   +3 more
doaj  

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source