Results 41 to 50 of about 245,319 (256)
Time-Based Binding as a Solution to and a Limitation for Flexible Cognition
Frontiers in Psychology, 2022 Why can’t we keep as many items as we want in working memory? It has long been debated whether this resource limitation is a bug (a downside of our fallible biological system) or instead a feature (an optimal response to a computational problem).
Mehdi Senoussi +2 more
doaj +1 more source
Memory-Efficient Frequent-Itemset Mining [PDF]
, 2022 Efficient discovery of frequent itemsets in large datasets is a key component of many data mining tasks. In-core algorithms---which operate entirely in main memory and avoid expensive disk accesses---and in particular the prefix tree-based algorithm FP ...
Schlegel, Benjamin +2 more
core +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Working memory capacity of crows and monkeys arises from similar neuronal computations
eLife, 2021 Complex cognition relies on flexible working memory, which is severely limited in its capacity. The neuronal computations underlying these capacity limits have been extensively studied in humans and in monkeys, resulting in competing theoretical models ...
Lukas Alexander Hahn +4 more
doaj +1 more source
Reconsidering Custom Memory Allocation [PDF]
, 2002 Programmers hoping to achieve performance improvements often use custom memory allocators. This in-depth study examines eight applications that use custom allocators.
Zorn, BG +5 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Memory limits : give us an answer! [PDF]
, 2000 Cowan has written a meticulous and thought-provoking review of the literature on short-term memory. However, reflections on one area of evidence, that of working memory span, shows the extent to which the research debate can be circumscribed by choice of
Towse, John N.
core
, 2010 We introduce logics and automata based on memory event clocks. A memory clock is not really reset: instead, a new clock is created, while the old one is still accessible by indexing. We can thus constrain not only the time since the last reset (which was
Ortiz, James +5 more
core +1 more source