Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Language Model Using Neural Turing Machine Based on Localized Content-Based Addressing
The performance of a long short-term memory (LSTM) recurrent neural network (RNN)-based language model has been improved on language model benchmarks.
Donghyun Lee +3 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Generalized associative memory models: Their memory capacities and potential application [PDF]
The Hopfield and bi-directional associative memory (BAM) models are well developed and carefully studied models for associative memory that are patterned after the memory structure of the animal brain. Their basic limitation is that they can only perform
Yap, Teddy N., Jr. +1 more
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ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Seeking explanation in theory: Reflections on the social practices of organizations that distribute public use microdata files for research purposes [PDF]
Public concern about personal privacy has recently focused on issues of Internet data security and personal information as big business. The scientific discourse about information privacy focuses on the cross-pressures of maintaining confidentiality and ...
Robbin, Alice, Koball, Heather
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ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
Towards a Neural Network Model of the Attentional Blink [PDF]
One of the most prominent experimental paradigms for investigating the deployment of attention over time is the Attentional Blink (AB). Although there is now a great deal known about it, computational modeling of the AB remains only lightly explored ...
Barnard, Philip +2 more
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Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
The Capacity of Visual Short Term Memory Determines the Bandwidth of Information Transfer into Visual Long Term Memory [PDF]
Visual long term memory (VLTM) research has shown that we are capable of learning a virtually infinite amount of visual information. At the same time, visual short term memory (VSTM) research has shown that there is a severe limitation in the amount of ...
Fukuda, Keisuke
core

