Results 41 to 50 of about 825,210 (300)
Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation [PDF]
, 2014 Autoimmune diseases are driven by immune cells that recognize self-tissues. A major goal for treatment strategies for autoimmune diseases is to turn off or tolerize self-reactive immune cells such as CD4 T cells that coordinate tissue damage in many ...
A. David +38 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Carnets, 2016 This article aims to enlighten the vital presence of the triple cultural heritage present in Semprun’s work, whose first language is Spanish, and to show the relationship he has established with French and German.
Ana M. Alves
doaj +1 more source
BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. [PDF]
PLoS ONE, 2015 Memory B cells (MBCs) and long-lived plasma cells (LLPCs) are responsible for immunological "memory", which can last for many years. The long-term survival niche for LLPCs in the bone marrow is well characterized; however, the corresponding niche for ...
Shuichi Funakoshi +5 more
doaj +1 more source
Genetic dissection of innate immune memory in Drosophila melanogaster
Frontiers in Immunology, 2022 Current studies have demonstrated that innate immunity possesses memory characteristics. Although the molecular mechanisms underlying innate immune memory have been addressed by numerous studies, genetic variations in innate immune memory and the ...
Chang Tang +2 more
doaj +1 more source
A computational model of evolution: haploidy versus diploidy [PDF]
, 1999 In this paper, the study of diploidy is introduced like and important mechanism for memory reinforcement in artificial environments where adaptation is very important.
Berlanga de Jesús, Antonio +3 more
core +1 more source
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
, 2015 Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The lack of memory property in the density form
Statistica, 2014 The celebrated lack of memory property is a unique property of the exponential distribution in the continuous domain. It is expressed in terms of equality of residual survival function with the survival function of the original distribution.
Rishideep Roy, Dilip Roy
doaj +1 more source
Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]
, 2016 Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core +2 more sources