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Memory T Cells in Pregnancy [PDF]
Frontiers in Immunology, 2019 Adaptations of the maternal immune response are necessary for pregnancy success. Insufficient immune adaption is associated with pregnancy pathologies such as infertility, recurrent miscarriage, fetal growth restriction, spontaneous preterm birth, and ...
Tom E. C. Kieffer +4 more
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Human CD4 memory T cells can become CD4+IL-9+ T cells. [PDF]
PLoS ONE, 2010 IL-9 is a growth factor for T- and mast-cells that is secreted by human Th2 cells. We recently reported that IL-4+TGF-beta directs mouse CD4(+)CD25(-)CD62L(+) T cells to commit to inflammatory IL-9 producing CD4(+) T cells.Here we show that human ...
Prabhakar Putheti +4 more
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Memory regulatory T cells in pregnancy
Frontiers in Immunology, 2023 Pregnancy requires the process of maternal immune tolerance to semi-allogeneic embryos. In contrast, an overreactive maternal immune system to embryo-specific antigens is likely to result in the rejection of embryos while damaging the invading placenta ...
Zeyang Chen +5 more
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T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells. [PDF]
PLoS ONE, 2013 Memory T cells are composed of effector, central, and memory stem cells. Previous studies have implicated that both T-bet and Eomes are involved in the generation of effector and central memory CD8 T cells.
Gang Li +6 more
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Memory T follicular helper CD4 T cells
Frontiers in Immunology, 2015 T follicular helper (Tfh) cells are the subset of CD4 T helper cells that are required for generation and maintenance of germinal center reactions and the generation of long-lived humoral immunity.
J. Scott eHale, Rafi eAhmed
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CD4(+)CD62L(+) central memory T cells can be converted to Foxp3(+) T cells. [PDF]
PLoS ONE, 2013 The peripheral Foxp3(+) Treg pool consists of naturally arising Treg (nTreg) and adaptive Treg cells (iTreg). It is well known that naive CD4(+) T cells can be readily converted to Foxp3(+) iTreg in vitro, and memory CD4(+) T cells are resistant to ...
Xiaolong Zhang +5 more
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Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells. [PDF]
PLoS ONE, 2010 CD8(+) T cells provide broad immunity to viruses, because they are able to recognize all types of viral proteins. Therefore, the development of vaccines capable of inducing long-lived memory CD8(+) T cells is desired to prevent diseases, especially those
Maiko Taneichi +3 more
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Sepsis-induced changes in differentiation, maintenance, and function of memory CD8 T cell subsets
Frontiers in Immunology, 2023 Formation of long-lasting memory lymphocytes is one of the foundational characteristics of adaptive immunity and the basis of many vaccination strategies.
Mohammad Heidarian +4 more
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Respiratory Research, 2022 Background SARS-CoV-2 pre-existing T-cell immune reactivity can be present in some people. A general perturbation of the main peripheral lymphocyte subsets has been described in severe COVID-19 patients, but very few studies assessed the general memory T-
Makhabbat Bekbossynova +11 more
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The extrinsic factors important to the homeostasis of allergen-specific memory CD4 T cells
Frontiers in Immunology, 2022 Memory T cells, which are generated after the primary immune response to cognate antigens, possess unique features compared to naïve or effector T cells. These memory T cells are maintained for a long period of time and robustly reactivate in lymphoid or
Aryeong Choi +2 more
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