Results 1 to 10 of about 1,044,819 (294)
T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells. [PDF]
PLoS ONE, 2013 Memory T cells are composed of effector, central, and memory stem cells. Previous studies have implicated that both T-bet and Eomes are involved in the generation of effector and central memory CD8 T cells.
Gang Li +6 more
doaj +14 more sources
Memory T follicular helper CD4 T cells [PDF]
Frontiers in Immunology, 2015 T follicular helper (Tfh) cells are the subset of CD4 T helper cells that are required for generation and maintenance of germinal center reactions and the generation of long-lived humoral immunity.
J. Scott eHale, Rafi eAhmed
doaj +3 more sources
CD4(+)CD62L(+) central memory T cells can be converted to Foxp3(+) T cells. [PDF]
PLoS ONE, 2013 The peripheral Foxp3(+) Treg pool consists of naturally arising Treg (nTreg) and adaptive Treg cells (iTreg). It is well known that naive CD4(+) T cells can be readily converted to Foxp3(+) iTreg in vitro, and memory CD4(+) T cells are resistant to ...
Xiaolong Zhang +5 more
doaj +6 more sources
Memory T Cells in Pregnancy [PDF]
Frontiers in Immunology, 2019 Adaptations of the maternal immune response are necessary for pregnancy success. Insufficient immune adaption is associated with pregnancy pathologies such as infertility, recurrent miscarriage, fetal growth restriction, spontaneous preterm birth, and ...
Tom E. C. Kieffer +4 more
doaj +4 more sources
B cells negatively regulate the establishment of CD49b+T-bet+ resting memory T helper cells in the bone marrow [PDF]
Frontiers in Immunology, 2016 During an immune reaction, some antigen-experienced CD4 T cells relocate from secondary lymphoid organs (SLOs) to the bone marrow (BM) in a CD49b-dependent manner and reside and rest there as professional memory CD4 T cells.
Shintaro eHojyo +11 more
doaj +4 more sources
Development and function of protective and pathologic memory CD4 T cells [PDF]
, 2015 Immunological memory is one of the defining features of the adaptive immune system. As key orchestrators and mediators of immunity, CD4 T cells are central to the vast majority of adaptive immune responses.
Jaigirdar, Shafqat Ahrar +1 more
core +18 more sources
T‐cell memory in tissues [PDF]
European Journal of Immunology, 2021 AbstractImmunological memory equips our immune system to respond faster and more effectively against reinfections. This acquired immunity was originally attributed to long‐lived, memory T and B cells with body wide access to peripheral and secondary lymphoid tissues.
van Gisbergen, Klaas P J M +2 more
openaire +4 more sources
Human CD4 memory T cells can become CD4+IL-9+ T cells. [PDF]
PLoS ONE, 2010 IL-9 is a growth factor for T- and mast-cells that is secreted by human Th2 cells. We recently reported that IL-4+TGF-beta directs mouse CD4(+)CD25(-)CD62L(+) T cells to commit to inflammatory IL-9 producing CD4(+) T cells.Here we show that human ...
Prabhakar Putheti +4 more
doaj +1 more source
Memory regulatory T cells in pregnancy
Frontiers in Immunology, 2023 Pregnancy requires the process of maternal immune tolerance to semi-allogeneic embryos. In contrast, an overreactive maternal immune system to embryo-specific antigens is likely to result in the rejection of embryos while damaging the invading placenta ...
Zeyang Chen +5 more
doaj +1 more source
Frontiers in Immunology, 2015 Immunological memory is a key feature of adaptive immunity. It provides the organism with long-lived and robust protection against infection. In organ transplantation, memory T cells pose a significant threat by causing allograft rejection that is generally resistant to immunosuppressive therapy.
Qianqian eZhang +2 more
openaire +3 more sources