Results 11 to 20 of about 1,044,819 (294)
Regulatory T cell memory [PDF]
Nature Reviews Immunology, 2015 Memory for antigen is a defining feature of adaptive immunity. Antigen-specific lymphocyte populations show an increase in number and function after antigen encounter and more rapidly re-expand upon subsequent antigen exposure. Studies of immune memory have primarily focused on effector B cells and T cells with microbial specificity, using prime ...
Rosenblum, Michael D +2 more
openaire +6 more sources
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. [PDF]
, 2020 The primary reservoir for HIV is within memory CD4+ T cells residing within tissues, yet the features that make some of these cells more susceptible than others to infection by HIV is not well understood.
Cavrois, Marielle +16 more
core +1 more source
Sepsis-induced changes in differentiation, maintenance, and function of memory CD8 T cell subsets
Frontiers in Immunology, 2023 Formation of long-lasting memory lymphocytes is one of the foundational characteristics of adaptive immunity and the basis of many vaccination strategies.
Mohammad Heidarian +4 more
doaj +1 more source
Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells. [PDF]
PLoS ONE, 2010 CD8(+) T cells provide broad immunity to viruses, because they are able to recognize all types of viral proteins. Therefore, the development of vaccines capable of inducing long-lived memory CD8(+) T cells is desired to prevent diseases, especially those
Maiko Taneichi +3 more
doaj +1 more source
The roles of resident, central and effector memory CD4 T cells in protective immunity following infection or vaccination [PDF]
, 2018 Immunological memory provides rapid protection to pathogens previously encountered through infection or vaccination. CD4 T cells play a central role in all adaptive immune responses.
Gray, Joshua I. +2 more
core +1 more source
Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation [PDF]
, 2014 Autoimmune diseases are driven by immune cells that recognize self-tissues. A major goal for treatment strategies for autoimmune diseases is to turn off or tolerize self-reactive immune cells such as CD4 T cells that coordinate tissue damage in many ...
A. David +38 more
core +1 more source
The extrinsic factors important to the homeostasis of allergen-specific memory CD4 T cells
Frontiers in Immunology, 2022 Memory T cells, which are generated after the primary immune response to cognate antigens, possess unique features compared to naïve or effector T cells. These memory T cells are maintained for a long period of time and robustly reactivate in lymphoid or
Aryeong Choi +2 more
doaj +1 more source
Respiratory Research, 2022 Background SARS-CoV-2 pre-existing T-cell immune reactivity can be present in some people. A general perturbation of the main peripheral lymphocyte subsets has been described in severe COVID-19 patients, but very few studies assessed the general memory T-
Makhabbat Bekbossynova +11 more
doaj +1 more source
, 2015 Memory T cells are usually considered to be a feature of a successful immune response against a foreign antigen, and such cells can mediate potent immunity. However, in mice, alternative pathways have been described, through which naïve T cells can acquire the characteristics and functions of memory T cells without encountering specific foreign antigen
Jameson, SC, Lee, YJ, Hogquist, KA
openaire +3 more sources
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets [PDF]
, 2005 Memory T cells are heterogeneous in terms of their phenotype and functional properties. We investigated the molecular profiles of human CD8 naive central memory (TCM), effector memory (TEM), and effector memory RA (TEMRA) T cells using gene expression ...
Callan, Margaret F C +4 more
core +1 more source