Results 1 to 10 of about 75,075 (182)

Tuberculosis preventive therapy in postpartum women with HIV modifies M. tuberculosis-specific and nonspecific immune responses [PDF]

Frontiers in Immunology
BackgroundTuberculosis (TB) has significant morbidity in pregnant and postpartum women with HIV (pregnant and PPWWHIV). TB preventive therapy (TPT) is recommended in pregnant and PPWWHIV with documented or presumed latent TB infection (LTBI).
Damayanti Yengkhom, Grace Montepiedra, Gaerolwe Masheto, Deo Wabwire, Lynda Stranix-Chibanda, Allen Matubu, Avy Violari, Gerhard Theron, Amita Gupta, Adriana Weinberg, Adriana Weinberg   +10 more
doaj   +2 more sources

Antibody persistence and immunologic memory in children vaccinated with 4 doses of pneumococcal conjugate vaccines: Results from 2 long-term follow-up studies [PDF]

Human Vaccines & Immunotherapeutics, 2017
To investigate long-term antibody persistence following the administration of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV), we present results of 2 follow-up studies assessing antibody persistence ...
Jacek Wysocki, Jerzy Brzostek, Ryszard Konior, Falko G. Panzer, Nancy A. François, Sudheer M. Ravula, Devayani A. Kolhe, Yue Song, Ilse Dieussaert, Lode Schuerman, Dorota Borys   +10 more
doaj   +2 more sources

Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. [PDF]

, 2012
BackgroundLimited knowledge exists on early HIV events that may inform preventive and therapeutic strategies. This study aims to characterize the earliest immunologic and virologic HIV events following infection and investigates the usage of a novel ...
Ananworanich, Jintanat, Chomchey, Nitiya, Chomont, Nicolas, de Souza, Mark, Dewar, Robin, Kim, Jerome H, Maldarelli, Frank, Marovich, Mary, Michael, Nelson, Paris, Robert, Peel, Sheila, Phanuphak, Nittaya, Phanuphak, Praphan, Pinyakorn, Suteeraporn, Rerknimitr, Rungsun, Rutvisuttinunt, Wiriya, RV254/SEARCH 010 Study Group, Schuetz, Alexandra, Sekaly, Rafick, Sereti, Irini, Trichavaroj, Rapee, Valcour, Victor, van Griensven, Frits, Vandergeeten, Claire   +23 more
core   +20 more sources

Dimensions of immunologic memory. [PDF]

Immunol Rev, 2018
Homann D, Kedl RM.
europepmc   +4 more sources

Single-cell profiling of T cells uncovers a tissue-resident memory-like T-cell subset associated with bidirectional prognosis for B-cell acute lymphoblastic leukemia

Frontiers in Immunology, 2022
IntroductionThe character and composition of leukemia-related T cells are closely related to the treatment response and prognosis for patients. Though B cell-acute lymphoblastic leukemia (B-ALL) patients have benefited from immune-based approaches, such ...
Wenpu Lai, Wenpu Lai, Wenpu Lai, Xiaofang Wang, Lian Liu, Ling Xu, Lipeng Mao, Jiaxiong Tan, Xianfeng Zha, Huien Zhan, Wen Lei, Yu Lan, Guobing Chen, Yangqiu Li, Yangqiu Li, Oscar Junhong Luo   +15 more
doaj   +1 more source

Maintenance and recall of memory T cell populations against tuberculosis: Implications for vaccine design

Frontiers in Immunology, 2023
Despite the widespread use of standardised drug regimens, advanced diagnostics, and Mycobacterium bovis Bacille-Calmette-Guérin (BCG) vaccines, the global tuberculosis (TB) epidemic remains uncontrollable. To address this challenge, improved vaccines are
Xin Liu, Haoran Li, Shanshan Li, Jinfeng Yuan, Yu Pang   +4 more
doaj   +1 more source

Frequency of CXCR3+ CD8+ T-Lymphocyte Subsets in Peripheral Blood Is Associated With the Risk of Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Development in Advanced HIV Disease

Frontiers in Immunology, 2022
BackgroundTuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a clinical aggravation of TB symptoms observed among a fraction of HIV coinfected patients shortly after the start of antiretroviral therapy (ART).
Rafael Tibúrcio, Rafael Tibúrcio, Rafael Tibúrcio, Gopalan Narendran, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Beatriz Barreto-Duarte, Artur T. L. Queiroz, Artur T. L. Queiroz, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Selvaraj Anbalagan, Kaustuv Nayak, Kaustuv Nayak, Narayanan Ravichandran, Rajasekaran Subramani, Lis R. V. Antonelli, Kumar Satagopan, Komathi Anbalagan, Brian O. Porter, Alan Sher, Soumya Swaminathan, Irini Sereti, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade, Bruno B. Andrade   +32 more
doaj   +1 more source

CAR-T Cells with Phytohemagglutinin (PHA) Provide Anti-Cancer Capacity with Better Proliferation, Rejuvenated Effector Memory, and Reduced Exhausted T Cell Frequencies

Vaccines, 2023
The development of genetic modification techniques has led to a new era in cancer treatments that have been limited to conventional treatments such as chemotherapy.
Gamze Gulden, Berranur Sert, Tarik Teymur, Yasin Ay, Nulifer Neslihan Tiryaki, Abhinava K. Mishra, Ercument Ovali, Nevzat Tarhan, Cihan Tastan   +8 more
doaj   +1 more source

Intradermal vaccination of adults with three low doses (2 µg) of recombinant hepatitis B vaccine. II. Persistence of immunity and induction of immunologic memory [PDF]

Memorias do Instituto Oswaldo Cruz, 2003
Of the 110 dentists who had presented seroconversion 50 days after the intradermal application of three 2 µg doses of the Belgian recombinant vaccine against hepatitis B (HB), administered eight years before at an interval of one month between the 1st ...
Maria do Carmo M Elisbão, José Luís da S Baldy, Ana Maria Bonametti, Edna Maria V Reiche, Helena K Morimoto, Rubens Pontello, Tiemi Matsuo, Antônio Ferelle, Jayme Neves   +8 more
doaj   +1 more source

Targeting memory T cell metabolism to improve immunity

The Journal of Clinical Investigation, 2022
Vaccination affords protection from disease by activating pathogen-specific immune cells and facilitating the development of persistent immunologic memory toward the vaccine-specific pathogen. Current vaccine regimens are often based on the efficiency of
Mauro Corrado, Erika L. Pearce
doaj   +1 more source