Results 11 to 20 of about 43,875 (259)

Redefining Non-Inferiority in Anamnestic Antibody Responses Using the Mean Increase of Log-Transformed Antibody Titers after Revaccination: Secondary Analysis of a Randomized Controlled Rabies Vaccination Trial

Vaccines, 2020
Non-inferiority in the anamnestic antibody response is conventionally determined by comparing seroconversion rates after revaccination. However, this approach is inadequate in the case of high pre-booster antibody titers.
Lisanne A. Overduin, Patrick H. P. Soentjens, Jelle J. Goeman, Magdalena A. Berkowska, Jacques J. M. van Dongen, Leo G. Visser   +5 more
doaj   +1 more source

Exposure to SARS-CoV-2 and Infantile Diseases

Global Medical Genetics, 2023
Background and Aim Immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in newborns and children after prophylactic immunization is currently a relevant research topic. The present study analyzes the issue by examining the
Darja Kanduc
doaj   +1 more source

Virus-induced asthma attack: The importance of allergic inflammation in response to viral antigen in an animal model of asthma. [PDF]

PLoS ONE, 2017
Asthma exacerbation can be a life-threatening condition, and is most often triggered by common respiratory viruses. Poor asthma control and worsening of respiratory function is associated with increased airway inflammation, including eosinophilia ...
Christopher Skappak, Ramses Ilarraza, Ying-Qi Wu, Matthew G Drake, Darryl J Adamko   +4 more
doaj   +1 more source

Immunological Memory in Innate Immunity [PDF]

Journal of Innate Immunity, 2013
‘trained immunity’. Trained immunity provides protection against reinfection in a T-/B-cell-independent manner, with nonspecific potentiation of inflammatory reactions and antimicrobial mechanisms playing a central role in these effects [4] . The current issue of the Journal of Innate Immunity presents a series of studies that shed additional light on ...
Netea, M.G., Netea, M.G.
openaire   +4 more sources

Memory T Cells in Pregnancy

Frontiers in Immunology, 2019
Adaptations of the maternal immune response are necessary for pregnancy success. Insufficient immune adaption is associated with pregnancy pathologies such as infertility, recurrent miscarriage, fetal growth restriction, spontaneous preterm birth, and ...
Tom E. C. Kieffer, Anne Laskewitz, Sicco A. Scherjon, Marijke M. Faas, Jelmer R. Prins   +4 more
doaj   +1 more source

Prolonged Impairment of Immunological Memory After Anti-CD20 Treatment in Pediatric Idiopathic Nephrotic Syndrome

Frontiers in Immunology, 2019
Anti-CD20 therapy is effective in idiopathic nephrotic syndrome (INS). However, transient or sustained hypogammaglobulinemia predisposing to an increased risk of infectious diseases can follow treatment in some patients. We analyzed the long-term effects
Manuela Colucci, Rita Carsetti, Jessica Serafinelli, Salvatore Rocca, Laura Massella, Antonio Gargiulo, Anna Lo Russo, Claudia Capponi, Nicola Cotugno, Ottavia Porzio, Andrea Onetti Muda, Paolo Palma, Francesco Emma, Francesco Emma, Marina Vivarelli, Marina Vivarelli   +15 more
doaj   +1 more source

PPAR agonists as effective adjuvants for COVID-19 vaccines, by modifying immunogenetics: a review of literature

Journal of Genetic Engineering and Biotechnology, 2021
Background Several coronavirus vaccine have been fast-tracked to halt the pandemic, the usage of immune adjuvants that can boost immunological memory has come up to the surface.
Antoine Fakhry AbdelMassih, Rahma Menshawey, Jumana H. Ismail, Reem J. Husseiny, Yousef M. Husseiny, Shenoda Yacoub, Aya Kamel, Rafeef Hozaien, Elaria Yacoub, Esraa Menshawey, Abanoub Abdelmalek, Ahmed Abouelazaem, Ahmed Elhatw, Ahmed Aboelmaaty, Alaaelrahman Shahib, Amany Mansour, Aya Kamal, Basant Mohamed, Bemen Atif, Beshoy Ghabreal, Catherine Abdelmalak, David Ibrahim, Ebtesam Elsaify, Farah Magdy, Farid G. Hanna, Hadeer Hafez, Hafsa Dahir, Kerlos Merhom, Maram Ahmed, Mariam Bishara, Mina Tawfik, Mina Youssef, Mohamed El Sharnouby, Mourad Hamouda, Musheera Ammar, Nada Ali, Nada Daniel, Nadine El-Husseiny, Noha Abdelraouf, Nuran K. Abdelhameed, Radwa Ahmed, Radwa Othman, Rahma Mohamadein, Rana Allam, Rana Elgendy, Rana Shebl, Saged Elsherbiney, Sarah Fouad, Sara Emel, Sara Owais, Sarah Hetta, Samah El-Saman, Shaimaa Abdelalim, Sherin Galal, Yara Asar, Yara Osman, Yasmeen Khalaf, Youstina Aziz, Yousra Khafagy, Nervana Gamal, Biagio Castaldi   +60 more
doaj   +1 more source

Case Report: Gene expression profiling of COVID-19 vaccination-related lymphadenopathies reveals evidence of a dominantly extrafollicular immune response

Frontiers in Immunology, 2023
mRNA-based vaccines against SARS-CoV-2 have been proven to be very efficient in preventing severe COVID-19. Temporary lymphadenopathy (LA) has been observed as a common adverse event following immunization.
Thomas Menter, Carl P. Zinner, Christoph T. Berger, Christoph T. Berger, Philip Went, Alexandar Tzankov   +5 more
doaj   +1 more source

Antigen-specific B memory cell responses to Plasmodium falciparum malaria antigens and Schistosoma haematobium antigens in co-infected Malian children. [PDF]

PLoS ONE, 2012
Polyparasitism is common in the developing world. We have previously demonstrated that schistosomiasis-positive (SP) Malian children have age-dependent protection from malaria compared to matched schistosomiasis-negative (SN) children.
Kirsten E Lyke, Amy Wang, Abdoulaye Dabo, Charles Arama, Modibo Daou, Issa Diarra, Christopher V Plowe, Ogobara K Doumbo, Marcelo B Sztein   +8 more
doaj   +1 more source

ON IMMUNOLOGICAL MEMORY

Annual Review of Immunology, 1996
▪ Abstract  Immunological memory is a hallmark of the immune system. Evolution can teach us which effector arms of immunological memory are biologically relevant against which virus. Antibodies appear to be the critical protective mechanism against cytopathic viruses.
Zinkernagel, R, Bachmann, M, Kündig, T, Oehen, S, Pirchet, H, Hengartner, H   +5 more
openaire   +4 more sources