Results 31 to 40 of about 75,193 (298)

Regulatory immune cells in transplantation [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Bushell, Andrew, Hester, Joanna, Wood, Kathryn J   +2 more
core   +1 more source

Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?

Frontiers in Immunology, 2021
Runx proteins (also known as Runt-domain transcription factors) have been studied for a long time as key regulators of cellular differentiation. RUNX2 has been described as essential for osteogenesis, whereas RUNX1 and RUNX3 are known to control blood ...
Svetlana Korinfskaya, Sreeja Parameswaran, Matthew T. Weirauch, Matthew T. Weirauch, Matthew T. Weirauch, Artem Barski, Artem Barski, Artem Barski   +7 more
doaj   +1 more source

Immunopathogenesis of rheumatoid arthritis [PDF]

, 2017
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
Ahmed, Ai, Ai, Anzilotti, Arend, Astorri, Benham, Bombardieri, Bottini, Bottini, Byng-Maddick, Catrina, Catrina, Charles-Schoeman, Christophorou, Corsiero, Croft, de Aquino, de Hair, Deane, Dennis, Diarra, Ekwall, El-Gabalawy, Ferreira, Filer, Firestein, Firestein, Firestein, Firestein, Firestein, Fonseca, Franz, Gary S. Firestein, Genovese, Hammaker, Harre, Hill, Horiuchi, Huber, Iain B. McInnes, Joosten, Juarez, Kaminsky, Karouzakis, Kelly, Kiener, Kim, Kinslow, Kirschmann, Klarenbeek, Konig, Konig, Krishnadas, Krishnamurthy, Källberg, Langley, Law, Lee, Lefèvre, Linn-Rasker, Liu, Lubberts, Lundström, Makrygiannakis, Matsumoto, McInnes, McInnes, McInnes, McInnes, McKellar, Miossec, Mydel, Müller-Ladner, Nakamachi, Nakano, Nakano, Nam, Okada, Pap, Perlman, Pitzalis, Randen, Rawlings, Raychaudhuri, Raza, Reynisdottir, Reynisdottir, Robertson, Rodríguez-Carrio, Rombouts, Rossetti, Scally, Scher, Schiff, Shi, Shi, Smolen, Smolen, Snir, Sokolove, Stanczyk, Suzuki, Tan, Tran, Tsaprouni, van Beers, van der Helm-van Mil, Vassallo, Wang, Wegner, Weyand, Yamamoto, Yang, Zhang, Zvaifler   +115 more
core   +1 more source

Inmunodeficiencia común variable: caracterización clínica e inmunológica de pacientes e identificación de subgrupos homogéneos con base en la tipificación de subpoblaciones de linfocitos B

Biomédica: revista del Instituto Nacional de Salud, 2015
Introducción. La inmunodeficiencia común variable es un síndrome heterogéneo caracterizado por infecciones recurrentes, hipogammaglobulinemia y producción deficiente de anticuerpos específicos.
Alejandra Catalina Vélez, Diana María Castaño, Rubén Darío Gómez, Julio César Orrego, Marcela Moncada, José Luis Franco   +5 more
doaj   +1 more source

Murine liver allograft transplantation: Tolerance and donor cell chimerism [PDF]

, 1994
Nonarterialized orthotopic liver transplantation with no immunosuppression was performed in 13 mouse‐strain combinations. Two strain combinations with major histocompatibility complex class I and class II and minor histocompatibility complex disparity ...
Arnold, Billingham, Billingham, Billingham, Calne, Calne, Cohen, Corry, Coutinho, Dahmen, Davies, Demetris, Demetris, Garnier, Goulmy, Hoffmann, Houssaint, Jerne, Kamada, Liegeois, Liegeois, Mayumi, Monaco, Monaco, Murase, Ono, Peacock, Perelson, Qian, Rao, Russell, Russell, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Steinman, Steinman, Strelein, Thomas, Wood, Zimmerman   +45 more
core   +1 more source

Immunologic difference between hypersensitivity to mosquito bite and hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection. [PDF]

PLoS ONE, 2013
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, virus-triggered immune disease. Hypersensitivity to mosquito bite (HMB), a presentation of Chronic Active Epstein-Barr Virus infection (CAEBV), may progress to HLH.
Wen-I Lee, Jainn-Jim Lin, Meng-Ying Hsieh, Syh-Jae Lin, Tang-Her Jaing, Shih-Hsiang Chen, Iou-Jih Hung, Chao-Ping Yang, Chin-Jung Chen, Yhu-Chering Huang, Shin-Pai Li, Jing-Long Huang   +11 more
doaj   +1 more source

Case report: ETS1 gene deletion associated with a low number of recent thymic emigrants in three patients with Jacobsen syndrome

Frontiers in Immunology, 2022
Jacobsen syndrome is a rare genetic disorder associated with a terminal deletion in chromosome 11. The clinical presentation is variable. Although immunodeficiency has been described in patients with Jacobsen syndrome, a clear genotype-phenotype ...
Tina Trachsel, Seraina Prader, Katharina Steindl, Jana Pachlopnik Schmid, Jana Pachlopnik Schmid   +4 more
doaj   +1 more source

Cellular size as a means of tracking mTOR activity and cell fate of CD4+ T cells upon antigen recognition. [PDF]

PLoS ONE, 2015
mTOR is a central integrator of metabolic and immunological stimuli, dictating immune cell activation, proliferation and differentiation. In this study, we demonstrate that within a clonal population of activated T cells, there exist both mTORhi and ...
Kristen N Pollizzi, Adam T Waickman, Chirag H Patel, Im Hong Sun, Jonathan D Powell   +4 more
doaj   +1 more source

A double-negative (IgD CD27 ) B cell population is increased in the peripheral blood of elderly people [PDF]

, 2009
The T cell branch of the immune system has been extensively studied in the elderly and it is known that the elderly have impaired immune function, mainly due to the chronic antigenic load that ultimately causes shrinkage of the T cell repertoire and ...
AQUINO, Alessandra, BULATI, Matteo, CANDORE, Giuseppina, CARUSO, Calogero, COLONNA ROMANO, Giuseppina, LIO, Domenico, PELLICANO', Mariavaleria, Vitello, S   +7 more
core   +1 more source

The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease

Arthritis Research & Therapy, 2018
Background Diagnosis of systemic autoimmune rheumatic diseases (SARD) relies on the presence of hallmark anti-nuclear antibodies (ANA), many of which can be detected years before clinical manifestations. However, ANAs are also seen in healthy individuals,
Yuriy Baglaenko, Nan-Hua Chang, Sindhu R. Johnson, Waleed Hafiz, Kieran Manion, Dario Ferri, Babak Noamani, Dennisse Bonilla, Sina Rusta-Sellehy, Larissa Lisnevskaia, Earl Silverman, Arthur Bookman, Carolina Landolt-Marticorena, Joan Wither   +13 more
doaj   +1 more source