Results 141 to 150 of about 307,394 (254)

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source

Quasi-statically actuated MEMS scanner with concentric vertical comb electrodes

Micro and Nano Systems Letters
A quasi-static (QS) MEMS mirror scanner with concentric vertical combs (CVC) is presented. The increase rate of overlapped area of the CVC, tends to show larger values and more uniform than that of conventional vertical combs, resulting in improved ...
Daehwan Chae, Do-hyeon Jeong, Seong-jong Yun, Kyoung-woo Jo, Jong-Hyun Lee   +4 more
doaj   +1 more source

TP53 mutations orchestrate partial EMT states in oral squamous cell carcinoma: spatially resolved and in vitro preliminary insights into tumour plasticity

The Journal of Pathology, EarlyView.
Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim, Hong Wan, Raju Kumar, Muy‐Teck Teh, Angray Kang, Emma Bailey, Hannah Cottom, Adrian Biddle, Inês Sequeira, Farida Fortune   +9 more
wiley   +1 more source

Oxypaeoniflorin Attenuates Alcohol‐Associated Liver Disease, Potentially Involving TEAD4‐Mediated Inflammatory Signaling Cascades

Phytotherapy Research, EarlyView.
Oxypaeoniflorin (Opae) alleviates alcohol‐associated liver disease (ALD) by suppressing the TEAD4‐NLRP3 transcriptional axis. In hepatocytes, Opae inhibits YAP/TEAD4‐mediated NLRP3 inflammasome activation, thereby downregulating Lipin1/Srebp1‐associated lipid dysregulation.
Jiang‐Tao Zhong, Hao Yue, Ze‐Hao Wang, Ming Liu, Hai‐Ming Sun, Jian Song   +5 more
wiley   +1 more source

Drift‐Corrected Monocular VIO and Perception‐Aware Planning for Autonomous Drone Racing

Journal of Field Robotics, EarlyView.
ABSTRACT The Abu Dhabi Autonomous Racing League (A2RL) x Drone Champions League (DCL) competition requires teams to perform high‐speed autonomous drone racing using only a single camera and a low‐quality inertial measurement unit—a minimal sensor set that mirrors expert human drone racing pilots.
Maulana Bisyir Azhari, Donghun Han, Je In You, Sung Jun Park, David Hyunchul Shim   +4 more
wiley   +1 more source

Optically Driven AuCu Alloying in Single Nanoparticles Revealed by In Situ TEM

Small, EarlyView.
In situ transmission electron microscopy with picosecond laser illumination reveals how single gold nanorods reversibly take up and release copper from their carbon support, forming homogeneous AuCu alloys. Laser fluence and illumination time serve as control parameters, making composition dynamically tunable, and with it the functional properties it ...
Francesca Scalerandi, Loriane Monin, Nathan J. Mowry, Wiebke Albrecht   +3 more
wiley   +1 more source

A Multimodal In‐Situ Liquid Phase TEM and Electrochemical Study on Boric Acid as Electrolyte Additive for Alkaline Zinc‐Air Batteries

Small Methods, EarlyView.
This study establishes a multimodal correlative workflow to bridge disparate analytical scales in battery research. By linking dynamic in‐situ liquid‐phase TEM at the nanoscale with microscale morphological analysis and macroscale electrochemistry, a comprehensive mechanistic evaluation of electrolyte additives is achieved.
Sarmila Dutta, Yasin Emre Durmus, Eunmi Im, Hongyu Sun, Hugo Pérez Garza, Shibabrata Basak, Hans Kungl, Hermann Tempel, Rüdiger‐A. Eichel   +8 more
wiley   +1 more source

A Spatio‐Temporal Dynamics Model for Indoor Environmental Forecasting

IEEJ Transactions on Electrical and Electronic Engineering, EarlyView.
Accurate forecasting of indoor environmental conditions is essential for intelligent building operations and comfort‐oriented controls. However, reliable prediction remains challenging due to spatial heterogeneity across sensing locations, complex multi‐modal interactions, and nonstationary temporal dynamics.
Goro Terumichi, Jiarui Li, Tatsuji Kimura, Hiroaki Nishi   +3 more
wiley   +1 more source

Compact, scan-pattern-switchable 2D piezoelectric MEMS mirror with 1D addressable scanning. [PDF]

J Microelectromech Syst
Yu J, Zhu Y, Birla M, Lee M, Yang Y, Filipov E, Wang TD, Oldham KR.   +7 more
europepmc   +1 more source

Blind Source Separation via Time‐Frequency Localization on Sound Spectrogram for Environmental Sound Source Attribution

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT As urban sound environments grow more complex, environmental monitoring increasingly demands not just sound‐level measurement but also source attribution. Current source recognition techniques can identify which sources are present in a mixture, but cannot measure each source's energy contribution, making accountability impossible.
Rui Hu, Zhihao Wu, Yuxin Lin, Yong Xu
wiley   +1 more source