Results 151 to 160 of about 2,391 (245)

Intraindividual cognitive variability predicts amyloid beta, tau PET, and dementia conversion in Down syndrome: a potential marker of cognitive resilience

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Adults with Down syndrome (DS) are at risk for Alzheimer's disease (AD), yet identifying the preclinical phase remains challenging. Intraindividual cognitive variability (IICV) may be a sensitive marker of early AD‐related changes but remains understudied in DS.
Luciana Mascarenhas Fonseca, Eardi Lila, Ali Shojaie, Jasmeer Chhatwal, Orestes Forlenza, Michal Schnaider Beeri, Sharon Krinsky‐McHale, Ann D. Cohen, Bradley T. Christian, Elizabeth Head, Mark Mapstone, Benjamin Handen, Beau M. Ances, Thomas Grabowski, Naomi S. Chaytor, Shahid Zaman, for the Alzheimer's Biomarkers Consortium‐ Down Syndrome (ABC‐DS) Investigators   +16 more
wiley   +1 more source

Energy‐Based Phase‐Locking State Analysis in Brain State Identification

Human Brain Mapping, Volume 47, Issue 8, June 1, 2026.
EPLSA constructs an energy landscape from BOLD phase synchrony, achieving superior brain state classification and providing novel stability metrics. It demonstrates strong clinical translatability in characterizing sleep–wake transitions and Alzheimer's disease.
Chenfei Ye, Ziyan Deng, Shiqing Cong, Chen Ran, Tao Gong, Shoulin Huang, Ting Ma   +6 more
wiley   +1 more source

Development of Selective Plane Illumination Surface Enhanced Raman Scattering Spectral Microscopy for Improved Cellular Imaging

Journal of Raman Spectroscopy, Volume 57, Issue 6, Page 1081-1092, June 2026.
Selective plane illumination (SPI) is combined with SERS spectral imaging to reduce background, improve image contrast, and enable improved spectroscopy from molecules on the surface of nanoparticles. This approach provides improved imaging and spectroscopy from nanoparticles in complex environments, such as biological cells.
Abigail E. Smith, Zachary D. Schultz
wiley   +1 more source

Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen, Jennifer Hosmer, Saurab Kishore Munshi, Riya Joshi, Ayaho Yamamoto, Horst J. Schirra, Peter Sly, Alastair G. McEwan, Ulrike Kappler   +8 more
wiley   +1 more source

Coaxial Dipole Array With Switching Transmit Sensitivities for Ultrahigh Field MRI

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3608-3615, June 2026.
ABSTRACT Purpose To investigate dipole antennas with electronically switchable transmit field patterns to improve flip angle homogeneity in ultra‐high field MRI. Methods Reconfigurable dipole elements that could produce two distinct electronically switchable B1+ field profiles were conceptualized and constructed.
Dario Bosch, Georgiy A. Solomakha, Felix Glang, Martin Freudensprung, Nikolai Avdievich, Klaus Scheffler   +5 more
wiley   +1 more source

Static and Dynamic Mechanical Behaviors of Electrostatic MEMS Resonator with Surface Processing Error. [PDF]

Micromachines (Basel), 2018
Feng J, Liu C, Zhang W, Hao S.
europepmc   +1 more source

AB‐MDMSBA—Not a Synthetic Cannabinoid Receptor Agonist

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study uses classical in vitro pharmacology approaches to establish that AB‐MDMSBA does not bind to or activate the cannabinoid CB1 receptor and therefore should not be classified as a synthetic cannabinoid receptor agonist. ABSTRACT Synthetic cannabinoids remain one of the most prominent classes of New Psychoactive Substances (NPS).
Monica Patel, Dharshini Ganeshan, Izzy Horgan, Hannah Partington, Michelle Glass   +4 more
wiley   +1 more source

Thermoresponsive Complex Coacervates as Advanced Carriers for Cell‐Laden Liquid‐Core Capsules for Biomedical Applications

Small, Volume 22, Issue 32, 8 June 2026.
A thermoresponsive complex coacervate is engineered to transport liquid‐core capsules loaded with human adipose‐derived stem cells, forming modular, hierarchically organized tissue‐forming units. This injectable platform enables precise spatial control while maintaining high cell viability, offering a versatile and bioinspired strategy for minimally ...
Luís P. G. Monteiro, Mariana Carreira, Julien Es Sayed, Marleen Kamperman, João M. M. Rodrigues, João Mano   +5 more
wiley   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, Volume 7, Issue 3, June 2026.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

Abnormal Stress Reduced miR‐330 Supplementation Alleviates Osteoarthritis Progression by Suppressing Osteochondral Catabolism

Aging Cell, Volume 25, Issue 6, June 2026.
Downregulation of miR‐330 under abnormal stress exacerbates catabolism in cartilage and subchondral bone, thereby promoting the progression of osteoarthritis. ABSTRACT Abnormal mechanical stress plays a crucial role in the progression of osteoarthritis (OA). Key factors regulating mechanical response remain to be explored. This study harvested synovium
Luxiang Zou, Kaiwen Yang, Chuyao Wang, Yeke Yu, Xiaoyu Zhang, Chuan Lu, Jieyun Zhao, An Qin, Dongmei He   +8 more
wiley   +1 more source