Results 81 to 90 of about 2,391 (245)

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Charge Pump Phase-Locked Loop-Based Frequency Conditioning of a MEMS Resonator

Journal of Low Power Electronics and Applications
MEMS resonators have attracted attention for their wide applications in highly accurate clock references, sensors, wireless communications, frequency control, etc.
Xinyuan Hu, Yanfeng Jiang
doaj   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Real-Time Tracking of the Dynamic Viscosity of Bitumen with Piezoelectric MEMS Resonators

Proceedings
This work demonstrates lab-scale monitoring of the dynamic viscosity of bitumen with piezoelectric MEMS resonators over a period of 120 h at an elevated temperature of 100 °C in air.
Suresh Alasatri, Michael Schneider, Johannes Mirwald, Bernhard Hofko, Ulrich Schmid   +4 more
doaj   +1 more source

Nonconventional Tether Structure for Quality Factor Enhancement of Thin-Film-Piezoelectric-on-Si MEMS Resonator. [PDF]

Micromachines (Basel), 2023
Awad M, Workie TB, Bao J, Hashimoto KY.
europepmc   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Piezoelectrically and Capacitively Transduced Hybrid MEMS Resonator with Superior RF Performance and Enhanced Parasitic Mitigation by Low-Temperature Batch Fabrication

Applied Sciences
This study investigates a hybrid microelectromechanical system (MEMS) acoustic resonator through a hybrid approach to combine capacitive and piezoelectric transduction mechanisms, thus harnessing the advantages of both transducer technologies within a ...
Adnan Zaman, Ugur Guneroglu, Abdulrahman Alsolami, Jing Wang   +3 more
doaj   +1 more source

A GHz Silicon-Based Width Extensional Mode MEMS Resonator with Q over 10,000. [PDF]

Sensors (Basel), 2023
Liu W, Lu Y, Chen Z, Jia Q, Zhao J, Niu B, Wang W, Hao Y, Zhu Y, Yang J, Yang F.   +10 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

MEMS Huygens Clock Based on Synchronized Micromechanical Resonators

Engineering
With the continuous miniaturization of electronic devices, microelectromechanical system (MEMS) oscillators that can be combined with integrated circuits have attracted increasing attention.
Xueyong Wei, Mingke Xu, Qiqi Yang, Liu Xu, Yonghong Qi, Ziming Ren, Juan Ren, Ronghua Huan, Zhuangde Jiang   +8 more
doaj   +1 more source