Results 61 to 70 of about 1,223 (121)

Challenges in molecular diagnosis of multiple endocrine neoplasia

Frontiers in Endocrinology
Multiple endocrine neoplasia (MEN) is a group of rare genetic diseases characterized by the occurrence of multiple tumors of the endocrine system in the same patient. The first MEN described was MEN1, followed by MEN2A, and MEN2B.
Pauline Romanet, Théo Charnay, Nicolas Sahakian, Thomas Cuny, Frédéric Castinetti, Anne Barlier   +5 more
doaj   +1 more source

RESULTADO DE DIAGNÓSTICO PRECOZ Y CIRUGÍA PROFILÁCTICA EN CARCINOMA MEDULAR HEREDITARIO DEL TIROIDES

Revista Médica Clínica Las Condes, 2018
Resumen: El cáncer medular de tiroides (CMT) es un tumor originado en las células parafoliculares tiroideas. En el 25% de los casos, los CMT son hereditarios y ocurren en el contexto de las neoplasias endocrinas múltiples tipo 2 (NEM2) A y B.
José Miguel Domínguez R-T
doaj   +1 more source

MEN2 phenotype in a family with germline heterozygous rare RET K666N variant

Endocrinology, Diabetes & Metabolism Case Reports
Multiple endocrine neoplasia type 2 (MEN2) is a hereditary cancer syndrome caused by germline-activating pathogenic variants in the RET proto-oncogene.
A La Greca, D Dawes, M Albuja-Cruz, C Raeburn, L Axell, L Ku, C Klein, C Marshall, L Fishbein   +8 more
doaj   +1 more source

Medullary thyroid cancer in MEN2 pediatric/adolescent carriers of RET mutation: genotype/phenotype correlation and outcome in a retrospective series of 23 patients

Frontiers in Oncology
BackgroundMultiple endocrine neoplasia type 2 syndrome (MEN2) is a hereditary disease resulting from mutations of the rearranged during transfection (RET) protooncogene subclassified into MEN2A [medullary thyroid carcinoma (MTC), pheochromocytoma, and ...
Guenda Di Benedetto, Ignazio Barca, Laura De Gregorio, Claudia Scollo, Fiorenza Gianì, Federica Martorana, Marco Russo, Francesco Frasca, Gabriella Pellegriti, Gabriella Pellegriti, Giulia Sapuppo   +10 more
doaj   +1 more source

Neoplasias endocrinas múltiples: de lo molecular a lo clínico

Revista Médica Clínica Las Condes
Resumen: Las neoplasias endocrinas múltiples (NEM) tipo 1, 2 (se subdivide en 2A y 2B), 4 y 5; constituyen síndromes genéticos hereditarios con un patrón de transmisión autosómico dominante.
Nelson Wohllk, MD, Consuelo Olave, MD
doaj   +1 more source

Megacolon Associated with Multiple Endocrine Neoplasia Type 2B: A Case Successfully Managed with Ileostomy. [PDF]

Surg Case Rep
Ikeda T, Hondo N, Kitazawa M, Nakamura S, Yamamoto Y, Miyazaki S, Kataoka M, Tanaka H, Ishizaka N, Shimizu T, Kuroiwa M, Yamamoto N, Soejima Y.   +12 more
europepmc   +1 more source

How to manage medullary thyroid carcinoma: current treatment strategies. [PDF]

Drugs Context
Saltiki K, Karapanou O, Michalaki M, Effraimidis G.   +3 more
europepmc   +1 more source

Solitary Mucosal Neuroma of the Hard Palate Without Multiple Endocrine Neoplasia Type 2B: A Rare Non-syndromic Case Report and Literature Review. [PDF]

Cureus
Ky H, Gupta S, Ramasamy P, Ghosh S, Urs AB.   +4 more
europepmc   +1 more source

Metastatic Medullary Thyroid Carcinoma in Multiple Endocrine Neoplasia Type 2B (MEN 2B) With RET M918T Mutation: Challenges in Long-Term Management and Targeted Therapy. [PDF]

Cureus
Rahman Z, Clark B, Ali K, Choudhry H, Weimer L, Parza K, Bastidas Mora G.   +6 more
europepmc   +1 more source

Predicting Structural Progression-Free Survival After Surgery for Medullary Thyroid Carcinoma. [PDF]

World J Surg
Ros-Madrid I, Febrero B, Cano-Mármol RP, Segura P, Ferrer M, Rodríguez JM.   +5 more
europepmc   +1 more source