Abstract Background Genetic epidemiological analyses of child and adolescent mental health often use data from prospective longitudinal cohorts. Missingness due to selective attrition is therefore an important potential source of bias in such analyses.
Meseret M. Bazezew +4 more
wiley +1 more source
Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]
Chang S, Shi K, Zhang M.
europepmc +1 more source
The role of rare copy number variants in early‐onset depression
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison +12 more
wiley +1 more source
Retraction: Assessing the Causal Association Between COVID-19 and Graves Disease: Mendelian Randomization Study. [PDF]
JMIR Publications Editorial Office.
europepmc +1 more source
Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser +6 more
wiley +1 more source
Lost in the System: The Labyrinth of Rare Disease Diagnosis
Peter Fish
doaj +1 more source
Bidirectional Mendelian randomization study reveals no causal association between polycystic ovary syndrome and IgA nephropathy. [PDF]
Wang X, Zhang R, Chai W, Peng X.
europepmc +1 more source
ABSTRACT Obesity and psychiatric disorders are the leading causes of global morbidity. Epidemiological studies suggest a bidirectional link between higher body mass index (BMI) and mental health outcomes, but the direction of causality remains uncertain due to confounding and reverse causation. We performed a Mendelian randomization (MR) analysis using
Perl Han Lee +4 more
wiley +1 more source
Causal relationship between birth weight, uric acid levels, and risk of gout: New insights from a bidirectional two-sample Mendelian randomization study. [PDF]
Yin M, Yin Y, Feng H.
europepmc +1 more source
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong +4 more
wiley +1 more source

