Results 81 to 90 of about 164,706 (214)
Arachidonic acid and colorectal adenoma risk: a Mendelian randomization study [PDF]
, 2018 Chelsea A Isom,1 Martha J Shrubsole,2,3 Qiuyin Cai,2 Walter E Smalley,4,5 Reid M Ness,5 Wei Zheng,2,3 Harvey J Murff3,6 1Department of General Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; 2Division of Epidemiology, Vanderbilt ...
Murff HJ +6 more
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Concept of Mendelian randomization. [PDF]
, 2015 Concept of Mendelian randomization.
Albert Hofman (107303) +8 more
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Journal of the Pakistan Medical AssociationObjective: To assess the causality between other diseases of digestive system and breast cancer. Method: The 2-sample Mendelian randomisation study was conducted in 2023 at the First Affiliated Hospital of Bengbu Medical University, Bengbu, China, using
Yan Wang +3 more
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Sleep disturbances and heart failure: observational study and Mendelian randomization study [PDF]
Introduction Sleep disturbances are prevalent among patients with heart failure (HF) and may trigger acute exacerbations of the condition. However, the causal relationship between sleep disturbances and HF remains uncertain.
Junwen Wang +6 more
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Association between type 1 diabetes mellitus and esophageal varices: a Mendelian randomization study [PDF]
Introduction Esophageal varices (EV) are dilated submucosal veins in the distal esophagus connecting the portal vein to the systemic circulation. Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease associated with a variety of cardiovascular ...
Kai Feng, Jiang Yuan, Min Li, Yanhui Wei
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The causal relationship between obesity and IgA nephropathy: a Mendelian randomization study
Linchuang shenzangbing zazhiObjectiveTo explore the potential causal relationship between obesity and IgA nephropathy through Mendelian randomization. MethodsSummary-level data from genome-wide association studies of obesity-related shapes (body mass index, percentage body fat ...
Peng-tao Dong +3 more
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Mendelian Randomisation Training materials [PDF]
, 2018 The folder contains training materials for the Mendelian Randomisation Course using simulated ALSPAC data developed by Nic Timpson and ...
Timpson, Nicholas, Northstone, Kate
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Investigating the Impact of Gut Microbiota on Gout Through Mendelian Randomization [PDF]
Chaoqun Tang,1 Lei Li,2 Xin Jin,2 Jinfeng Wang,2 Debao Zou,2 Yan Hou,2 Xin Yu,2 Zhizhou Wang,2 Hongjiang Jiang1,2 1The First Clinical Medical School, Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2Department of ...
Jin X +8 more
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Introduction to Mendelian randomization
Annals of Clinical EpidemiologyMendelian randomization (MR), i.e. instrumental variable analysis using genetic instruments, is an approach that incorporates population genetics to improve causal inference. Given that genetics are randomly allocated at conception, this resembles the randomization process in randomized controlled trials and hence is more resistant to unobserved ...
Yeung, Shiu Lun Au +3 more
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Kidney International ReportsMendelian randomization leverages the random assortment of alleles at conception to investigate how genetically mediated changes in an exposure affect an outcome while minimizing concerns related to reverse causation and unmeasured confounding. Initially
Abigail J. Berube +3 more
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