This study employed a two‐sample Mendelian randomization approach to assess the causal relationship between autoimmune liver diseases (AILD) and diabetes mellitus. We found that genetic predispositions to primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) were significantly associated with an increased risk of type 1 diabetes ...
Haixia Kuang+9 more
wiley +1 more source
Editorial: Mendelian randomization and cardiovascular remodeling. [PDF]
Qiang J+8 more
europepmc +1 more source
Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease
Despoina Manousaki+4 more
openalex +1 more source
Impact of particulate matter exposure on melanoma risk: A multicentre case–control study
Long‐term exposure to higher levels of PM10 and PM2.5 may have a protective effect against melanoma, potentially due to the reduction in ultraviolet radiation. Abstract Background The relationship between particulate matter (PM) exposure and melanoma risk remains largely unexplored.
Francesco Bellinato+8 more
wiley +1 more source
Glucokinase activator, circulating metabolites, and cardio-cerebrovascular diseases: a Mendelian randomization study. [PDF]
Wang X+6 more
europepmc +1 more source
Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease
ABSTRACT Background and Aim The effect of Helicobacter pylori (H. pylori) infection and eradication on the risk of gastroesophageal reflux disease (GERD) is still unclear. Methods We conducted a systematic review with a comprehensive literature search in the bibliographic databases Embase, Medline, and Cochrane Library through May 2024.
Hejie Wang+8 more
wiley +1 more source
Bidirectional Mendelian randomization analysis reveals the causal effects of nutrients on arthropathies. [PDF]
Xu W, Xia R, Peng D, Chen X.
europepmc +1 more source
Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah+8 more
wiley +1 more source
Autism spectrum disorders and childhood caries: a comprehensive Mendelian randomization study. [PDF]
Jin Q+6 more
europepmc +1 more source