Results 211 to 220 of about 81,479 (293)

A Principled Framework for Mendelian Randomization in Oral Health Research

Journal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir, Mario Romandini, Moritz Kebschull, Konstantinos K. Tsilidis, Dominique S. Michaud, Stephen Burgess   +5 more
wiley   +1 more source

Mendelian randomization reveals DNA methylation-related pyroptosis genes associated with psoriasis risk. [PDF]

Clin Epigenetics
Dong W, Shi C.
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Causal associations between ankylosing spondylitis and cardiovascular disease: a mendelian randomization analysis. [PDF]

Clinics (Sao Paulo)
Zhou L, Tang Y, Jiang J.
europepmc   +1 more source

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies [PDF]

, 2019
Heath, Andrew C., Humphreys, Benjamin D., Madden, Pamela A. F., Wu, Haojia   +3 more
core   +1 more source

Sarcopenia-related traits and erectile dysfunction: a bi-directional Mendelian randomization study. [PDF]

Sex Med
Jianxin X, Wensong W, Dengpan F, Yiwei W, Fangmin C.   +4 more
europepmc   +1 more source

On the use of Mendelian randomization to infer causality in observational epidemiology [PDF]

, 2017
Bochud, Murielle
core  

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, EarlyView.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

Programmed cell death and risk of diabetic retinopathy: a Mendelian randomization study. [PDF]

J Transl Med
Chen Y, Xu H, Wei H, Zhao R, Tan Y, Lin H, Li N.   +6 more
europepmc   +1 more source