Results 201 to 210 of about 81,479 (293)

Kidney function decline and kidney stone risk: cohort and Mendelian randomization analyses. [PDF]

Ren Fail
Yuan C, Sha L, Xue B, Jiang X, Jian Z.
europepmc   +1 more source

Concurrence of the Core Mechanistic Tenets of the American Heart Association Statement on the Cardiovascular–Kidney–Metabolic Syndrome and the Adipokine Hypothesis of Heart Failure With Preserved Ejection Fraction

Diabetes, Obesity and Metabolism, EarlyView.
Milton Packer
wiley   +1 more source

Causal effects of lifestyle and socioeconomic factors on diabetes and its complications and comorbidities: A Mendelian randomization study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Diabetes poses a growing global health burden. This study investigated the causal effects of lifestyle and socioeconomic factors on diabetes risk and related complications and comorbidities. Materials and Methods We applied two‐sample univariable and multivariable Mendelian randomization to assess the causal impact of 26 lifestyle and ...
Qian Yu, Zhaowei Kong, Qingde Shi, Chak Kwong Cheng, Jia Zhang, Jinlei Nie   +5 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

PHEWAS, TWAS, Mendelian Randomization in Osteoporosis Research: the good, the bad, and the ugly. [PDF]

Curr Osteoporos Rep
Li S, Trajanoska K.
europepmc   +1 more source

Breeding 5.0: Artificial intelligence (AI)‐decoded germplasm for accelerated crop innovation

Journal of Integrative Plant Biology, EarlyView.
ABSTRACT Crop breeding technologies are vital for global food security. While traditional methods have improved yield, stress tolerance, and nutrition, rising challenges such as climate instability, land loss, and pest pressure now demand new solutions.
Jiayi Fu, Shouzhi Zheng, Longjiang Fan, Xiaoming Zheng, Qian Qian   +4 more
wiley   +1 more source

Causal Effects of Common Pregnancy Complications on Neonatal Birth Weight: A Mendelian Randomization Study. [PDF]

Int J Womens Health
Qu D, Liu J, Peng X, Dou H, Huang L, Lin H, Yang L, Wang Y.   +7 more
europepmc   +1 more source

Constitution and function of intergenic genome regions in cultivated versus annual wild soybean in China

Journal of Integrative Plant Biology, EarlyView.
Three‐case restricted two‐stage multi‐locus multi‐allele genome‐wide association study identified main‐effect genes and detected the regulatory effects of intergenic loci on genes, enabling comprehensive dissection of the genic‐intergenic genetic system for quantitative traits and providing a strategy for studying their genetic basis.
Xiaoshuai Hao, Xinyang Hu, Yongpeng Pan, Qi Zhang, Ran Ou, Fenfen Jiang, Fangdong Liu, Jiaoping Zhang, Wubin Wang, Guangnan Xing, Junyi Gai, Jianbo He   +11 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Glycolysis-related genes for bladder cancer: A Mendelian randomization analysis. [PDF]

Biochem Biophys Rep
Hong X, Wang G, Hong T, Liu X, Lin S, Liu G, Lin W, Zhang Y.   +7 more
europepmc   +1 more source