Results 181 to 190 of about 143,068 (301)

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Causal relationship between asthma and hernia risk: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Lu Y, Yuan H, Li D, Yang G, Liu X, Wang X, Zhang K, Liu D.   +7 more
europepmc   +1 more source

Obstructive Sleep Apnea and BMI, Body Fat Percentage in the East Asian Population: A Bidirectional and Multivariate Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan, Wen‐Jun Lu, Hua Zhang, Hai‐Ling Jiang, Tao Li, Yan Yan   +5 more
wiley   +1 more source

Mendelian randomization of risk factors for premenstrual disorders. [PDF]

Npj Ment Health Res
Yang Y, Tang B, Hysaj E, Xiang N, Qu S, Hägg S, Valdimarsdóttir UA, Bertone-Johnson E, Lu Y, Lu D.   +9 more
europepmc   +1 more source

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang, Yu‐Wan Song, Yan Wang, Kun Zhao, Hu‐Hui‐Fen He, Jing‐Jing Qiu, Da‐Wei Liu, Bo Li, Yan Sun   +8 more
wiley   +1 more source

Metabolic Markers of MRI-Confirmed Lacunar Stroke: Observational and Mendelian Randomization Analyses. [PDF]

Neurology
Ng WH, Aghakishiyeva E, Markus HS, Harshfield EL.   +3 more
europepmc   +1 more source

Causal relationship between sex hormones and ischemic stroke risk: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Huang Q, Li Q, Guo JH.
europepmc   +1 more source

Mendelian randomization analysis

Mendelian randomization ...
openaire   +1 more source

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source

Mendelian randomization analysis of inflammatory proteins and lung adenocarcinoma risk. [PDF]

Discov Oncol
Tan H, Ma S, Liu Y.
europepmc   +1 more source