Results 171 to 180 of about 81,479 (293)

Bidirectional and Multivariable Mendelian Randomization Study of PCOS and VTE. [PDF]

Int J Womens Health
You L, Cui H, Zhao F, Huang H, Xu W.
europepmc   +1 more source

Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High‐Sensitivity C‐Reactive Protein Levels

Acta Paediatrica, EarlyView.
ABSTRACT Aim This Prospective, Community‐Based Cohort Study Investigated Cardiovascular Health and Its Association With Low‐Grade Inflammation in Adolescents. Methods Data were collected by specially trained medical staff from 1379 Austrian adolescents aged 14–19 years from 3 February 2021 to 28 February 2023.
Katharina Mueller, Alex Messner, Johannes Nairz, Ursula Kiechl‐Kohlendorfer, Michael Knoflach, Sophia Zollner‐Kiechl, Early Vascular Ageing in the Youth study group   +6 more
wiley   +1 more source

Cerebrospinal fluid and plasma metabolites in Parkinson's disease: a Mendelian randomization study. [PDF]

Sci Rep
Wang JL, Zhao Q, Zheng R, Fang Y, Cao J, Zhang BR.   +5 more
europepmc   +1 more source

Circulating levels of insulin‐like growth factor I (IGF‐I) and risk of multiple myeloma: An observational and Mendelian randomisation study

British Journal of Haematology, EarlyView.
Summary Evidence for an association between insulin‐like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF‐I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two‐sample Mendelian randomisation (MR) analysis using identified ...
Yolanda Benavente, Sara Hermosa, Nikos Papadimitriou, Alyssa Clay‐Gilmour, Elizabeth E. Brown, Jonathan N. Hofmann, Nathaniel Rothman, Qing Lan, Sonja I. Berndt, Demetrius Albanes, Mark Purdue, Mitchell J. Machiela, Stephen J. Chanock, Parveen Bhatti, Wendy Cozen, Aaron Norman, Susan L. Slager, James R. Cerhan, Vincent Rajkumar, Shaji K. Kumar, Celine M. Vachon, Anne J. Novak, Thomas M. Habermann, Brian K. Link, Gilles Salles, Herve Ghesquieres, Paige M. Bracci, Elizabeth Holly, Rosalie G. Griffin, Michelle A. T. Hildebrandt, Roel C. H. Vermeulen, P. Martijn Kolijn, Henrik Hjalgrim, Karin Ekström Smedby, Harindra Jayasekara, Simon Cheah, Alain Monnereau, Yu Chen, Alan Arslan, Yawei Zhang, Nicola J. Camp, Douglas W. Sborov, Afaf E. G. Osman, Elad Ziv, Immaculata De Vivo, Vijai Joseph, Lauren R. Teras, Alpa V. Patel, Eleanor Kane, Claire M. Vajdic, Adrien Guilloteau, Pierluigi Cocco, Laia Alemany, Juan Sainz, James McKay, Brenda M. Birmann, Delphine Casabonne   +56 more
wiley   +1 more source

Winner's Curse Free Robust Mendelian Randomization with Summary Data. [PDF]

J Am Stat Assoc
Xie Z, Zhang W, Wang J, Wu C.
europepmc   +1 more source

Hyperthyroidism drives gout risk: A Mendelian randomization observational study. [PDF]

Medicine (Baltimore)
Pan Y, Zhou S, Luo D.
europepmc   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source

Gene-environment equivalence: The fundamental principle of Mendelian randomization. [PDF]

PLoS Med
Davey Smith G, Hemani G, Ebrahim S.
europepmc   +1 more source

Sleep Efficiency Predicts Next‐Day Glycaemia and Daytime Glycaemia Influences Sleep in Free‐Living Adults at Risk of Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To investigate how sleep features influence next‐day diurnal glucose homeostasis and vice versa in free‐living adults at risk of type 2 diabetes. Materials and Methods This observational repeated‐measures study included 388 adults aged 25–65 years (50% women) with overweight or obesity (BMI ≥ 25.0–< 40.0 kg/m2).
Antonio Clavero‐Jimeno, Juan J. Martin‐Olmedo, Jairo H. Migueles, Alba Camacho‐Cardenosa, Marcos Molina‐Fernandez, Manuel Dote‐Montero, Jordi Merino, Manuel Muñoz‐Torres, Idoia Labayen, Jonatan R. Ruiz   +9 more
wiley   +1 more source

Insomnia-Driven Hippocampal Atrophy: Evidence From Bidirectional Mendelian Randomization. [PDF]

Health Sci Rep
Han D, Li X, Zhao S, Liu J, Wang X, Jiang Y, Ding J, Wang B, Cui E, Huang D.   +9 more
europepmc   +1 more source