Results 191 to 200 of about 81,479 (293)

The Gut Microbiome as a Therapeutic Target in Alopecia Areata: Not Yet Part of the Patient Treatment Plan

International Journal of Dermatology, EarlyView.
ABSTRACT Interest in the gut microbiome as a therapeutic target for treating alopecia areata (AA) has grown considerably. However, existing evidence remains limited and inconsistent. Currently, there is insufficient evidence to recommend microbiome‐directed testing and therapies to patients with AA.
Eric McMullen, Deema Abdel Hafeez, Nikhil Pai, Laurence Mainville, Shireen Dumont, Narachai Julanon, Romy Shenderey, Grace Xiong, Shahnawaz Towheed, Jeffrey Donovan   +9 more
wiley   +1 more source

Serum Levels and Genetic Variants of CC16: Associations With Asthma and Lung Function Development

Clinical &Experimental Allergy, EarlyView.
Hans Jacob L. Koefoed, Yidan Sun, Ilse Hugtenburg, Stefano Guerra, Ulrike Gehring, Roel Vermeulen, Judith M. Vonk, Gerard H. Koppelman   +7 more
wiley   +1 more source

Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez, C. Hervás‐Rivero, R. Rodríguez‐Bermúdez, D. López‐Carbonell, M. Hermida, P. Martínez, L. Varona   +6 more
wiley   +1 more source

Genetic predisposition to smoking and the risk of Carpal Tunnel Syndrome: a mendelian randomization study. [PDF]

Clinics (Sao Paulo)
Zeng Q, Rao X, Hu W, Chao H, Cheng Y, Zheng G.   +5 more
europepmc   +1 more source

Use of Cluster Analysis for Identifying Metafounders

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In the metafounder approach, the relationship matrix of metafounders, Γ$$ \boldsymbol{\Gamma} $$ is used to transfer information on relationships between pedigree founders into the numerator relationship matrix A$$ \mathbf{A} $$, creating matrix AΓ$$ {\mathbf{A}}^{\boldsymbol{\Gamma}} $$.
Christine Anglhuber, Christian Edel, Eduardo C. G. Pimentel, Reiner Emmerling, Kay‐Uwe Götz, Georg Thaller   +5 more
wiley   +1 more source

Estimation of Genetic Variance and Breeding Values for Infectious Disease Susceptibility From Simulated Longitudinal Data Using Generalized Linear Mixed Models Based on Transmission Dynamics

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Recent theoretical work shows that the potential of genetic selection to reduce the prevalence of infectious diseases is much larger than expected from classical quantitative genetic theory, due to indirect genetic effects that arise in the transmission process. However, to fully benefit from these indirect effects, we need to estimate genetic
A. D. Hulst, R. Pong‐Wong, A. Doeschl‐Wilson, M. C. M. De Jong, P. Bijma   +4 more
wiley   +1 more source

Disentangling the Effect of BMI on Hepatocellular Carcinoma From Cirrhosis With Multivariable Mendelian Randomization. [PDF]

Liver Int
Gkatzionis A, Sanderson E, Smith GD, Stender S, Gellert-Kristensen H.   +4 more
europepmc   +1 more source

Vitamin D supplementation in the first 2 years and autism spectrum traits at 6–8 years – a randomized clinical trial

Journal of Child Psychology and Psychiatry, EarlyView.
Background Early life vitamin D levels may be associated with autism spectrum disorder (ASD) and related traits, but causality is unknown. We examine whether higher‐than‐standard vitamin D3 supplementation during the first 2 years, as well as higher pregnancy and childhood 25‐hydroxyvitamin D (25(OH)D) levels and their trajectories, are associated with
Samuel Sandboge, Vilja Seppälä, Sakari Lintula, Elisa Holmlund‐Suila, Helena Hauta‐alus, Eero Kajantie, Outi Mäkitie, Sture Andersson, Katri Räikkönen, Kati Heinonen   +9 more
wiley   +1 more source

Causal Effect of Low-Density Lipoprotein Cholesterol on Chronic Kidney Disease: A Mendelian Randomization Study. [PDF]

Biochem Res Int
Zhou D, Zheng K, Zhang S, Zheng B.
europepmc   +1 more source

Violent and sexual victimisation and incident anxiety, mood and substance use disorders in childhood and adolescence: a co‐sibling study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Studies on the association between victimisation in childhood and adolescence and psychiatric disorders increasingly acknowledge that these associations might be partly confounded by unmeasured familial factors. However, previous quasi‐experimental evidence is largely based on retrospective self‐reported data with potential response biases ...
Joonas Pitkänen, Amir Sariaslan, Lauren Bishop, Mikko Aaltonen, Laura Mielityinen, Taina Laajasalo, Noora Ellonen, Pekka Martikainen   +7 more
wiley   +1 more source