Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru +2 more
wiley +1 more source
Use of Mendelian Randomization to Unveil Metabolic Markers in <i>Helicobacter pylori</i> Infection. [PDF]
Hoang T, Kim J.
europepmc +1 more source
This split‐mouth randomized clinical trial showed that platelet‐rich fibrin impregnation of a volume‐stable collagen matrix did not improve clinical, esthetic, or patient‐reported outcomes compared with collagen matrix alone for multiple gingival recession treatment after 6 months. ABSTRACT Aim This split‐mouth randomized clinical trial aimed to assess
Gabriel Leonardo Magrin +6 more
wiley +1 more source
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Viruses, Periodontitis, and Systemic Diseases
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
Rheumatoid arthritis and airway hyperresponsiveness: A GWAS-based mendelian randomization study. [PDF]
Shu H +8 more
europepmc +1 more source
Causal Inference in Clinical Research: A Primer
Causal inference helps researchers move beyond describing associations to answering the question: what would happen if an exposure were changed? This article provides an intuitive overview for applied researchers. ABSTRACT The study of causal relationships is central to scientific inquiry. Understanding what disease is, why it arises, and how it can be
Nasir Z. Bashir +3 more
wiley +1 more source
Exploring the Causality Between Mood Swings and Neurological Diseases: A Mendelian Randomization Study. [PDF]
Li N +5 more
europepmc +1 more source
Genomic Evidence on Antihypertensive Drug Targets and Oral Disease Outcomes
Key Findings Drug‐target Mendelian randomization showed little evidence that genetically proxied on‐target pharmacological actions of most antihypertensive drug classes were associated with chronic periodontitis or dental caries. The diazoxide–periodontitis association requires cautious interpretation, given possible residual pleiotropy at KCNJ11 and ...
Aiswarya Puzhakkara Chennas +7 more
wiley +1 more source
Genetic Causal Association Between Vitamin E and Depression: A Two-Sample Mendelian Randomization Study. [PDF]
Zhao D, Long X, Wang J.
europepmc +1 more source

