Results 81 to 90 of about 18,346 (199)

Endometrial stromal Menin supports endometrial receptivity by maintaining homeostasis of WNT signaling pathway through H3K4me3 during WOI

Communications Biology
Dysregulated endometrial receptivity is a well-established critical factor that contributes to recurrent implantation failure (RIF). Decidualization of stromal cells and differentiation of epithelial cells in the endometrium are crucial processes for ...
Xin Xu, Yichen Han, Keer Jin, Weina Xu, Huanyu Zhang, Yana Ma, Xiangjuan Li, Haibin Wang, Mengying Liu, Xiaona Lin   +9 more
doaj   +1 more source

Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular carcinoma survival

Cell Reports
Summary: Chromatin regulators are frequently mutated or aberrantly expressed in hepatocellular carcinoma (HCC), suggesting that the dysregulation of chromatin is a key feature driving liver cancer.
Margarita Dzama-Karels, Mallory Sokolowski, Peyton Kuhlers, Jacqueline A. Brinkman, John P. Morris, IV, Jesse R. Raab   +5 more
doaj   +1 more source

Mario Menin. camicia nera futurista e primo battaglista del mondo

Mario Menin : camicia nera futurista e primo battaglista del mondo / (presentazione di Filippo Tommaso Marinetti e Luigi Scrivo). - Roma : Edizioni futuriste di poesia, stampa 1941 Dedica manoscritta dell\u27autore: A Bodrero Emilio / con ammirazione ...
Menin, Mario
core  

Menin : a new actor in cell cycle ?

, 2011
La NEM1 est un syndrome cancéreux affectant de nombreuses glandes endocrines, qui résulte d’une prédisposition génétique liée à des mutations du gène MEN1.
Ivo, Dina Isabel Antunes-
core  

Menin enhances c-Myc-mediated transcription to promote cancer progression

Nature Communications, 2017
Menin is a protein with context-dependent oncogenic or oncosuppressive roles; the oncogenic activity is mainly due to its function as a cofactor of the MLL1 histone methyltransferase complex.
Gongwei Wu, Mengqiu Yuan, Shengqi Shen, Xiaoyu Ma, Jingwen Fang, Lianbang Zhu, Linchong Sun, Zhaoji Liu, Xiaoping He, De Huang, Tingting Li, Chenchen Li, Jun Wu, Xin Hu, Zhaoyong Li, Libing Song, Kun Qu, Huafeng Zhang, Ping Gao   +18 more
doaj   +1 more source

Menin [PDF]

, 2020
openaire   +2 more sources

Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT

Journal of Translational Medicine
Background Our previous studies found that Menin was highly expressed in gastric cancer (GC) and could promote GC progression. Tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) and their exosomes plays pivotal roles in GC.
Shan-Hu Wang, Jin-Xun Jiang, Kai-Tian Zheng, Shi-Jie Zhang, Tian-De Chen, Zhen Wang   +5 more
doaj   +1 more source

Targeting menin [PDF]

Nature Reviews Cancer, 2012
openaire   +2 more sources

Menin inhibitors for acute myeloid leukemia: latest updates from the 2023 ASH Annual Meeting

Journal of Hematology & Oncology
Recent developments in menin inhibitors for relapsed or refractory acute myeloid leukemia (AML) were highlighted at the 2023 ASH Annual Meeting. Notably, revumenib showed promising efficacy, achieving a 100% ORR when combined with decitabine/cedazuridine
Zhuo-Yu An, Xiao-Hui Zhang
doaj   +1 more source

Menin-driven mTOR signaling sustains taxane resistance in CRPC and reveals a targetable vulnerability for combination therapy

Cell Communication and Signaling
Prostate cancer (PC) progression is predominantly driven by androgen signaling, making androgen deprivation therapy (ADT) the standard treatment. However, the transition to castration-resistant prostate cancer (CRPC) significantly reduces ADT efficacy ...
Ipek Bulut, Buse Cevatemre, Neslihan Yuksel-Catal, Hamzah Syed, Tamer Onder, Ceyda Acilan   +5 more
doaj   +1 more source