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Repotrectinib’s Clinical Benefit and Its Brain Penetration in a Patient with Meningeal Carcinomatosis from G2032R-Mutated ROS-1 Positive Non-Small Cell Lung Cancer [PDF]
Oncology and Therapy, 2023 In this work, we report on a clinically significant response of meningeal carcinomatosis to repotrectinib in a woman with a heavily pretreated ROS1-rearranged non-small cell lung cancer (NSCLC) that harbored the concomitant solvent front G2032R mutation.
Giulio Metro +12 more
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Metastatic Meningeal Carcinomatosis From Lung Cancer: Report of a Rare Case [PDF]
Thoracic Cancer, 2020 Meningeal carcinomatosis (MC) refers to the diffuse or multifocal spread or infiltration of malignant tumors in the pia mater. It is a special distribution type of metastatic tumors in the central nervous system and one of the important reasons of death ...
Hui Liu
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Meningeal carcinomatosis in solid tumors [PDF]
Arquivos de Neuro-Psiquiatria, 2011 The involvement of the leptomeninges by metastatic tumors can be observed in solid tumors, in which case it is termed meningeal carcinomatosis (MC), and in lymphoproliferative malignant disease.
Sandro José Martins +5 more
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Characteristics of Patients With Meningeal Carcinomatosis Combined With Myelopathy [PDF]
Neuropsychiatric Disease and Treatment, 2022 Lidong Jiao,1 Min Wei,1 Yongjuan Fu2 1Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, People’s Republic of China; 2Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, People’s ...
Lidong Jiao, Yongjuan Fu
exaly +4 more sources
Meningeal carcinomatosis secondary to neurenteric cysts with malignant transformation: a case report [PDF]
BMC Neurology, 2022 Background Meningeal carcinomatosis is mainly associated with breast cancer, lung cancer, and melanoma. However, meningeal carcinomatosis secondary to a neurenteric cyst with malignant features is extremely rare. Case presentation We report the case of a
Min Chu +6 more
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Brazilian Neurosurgery, 2021 Introduction Cerebral metastases are the most common cancer of the central nervous system (CNS). Meningeal infiltration by neoplasms that did not originate in the CNS is a rare fact that is present in 0.02% of the autopsies.
Tiago Silva Holanda Ferreira +4 more
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Meningeal carcinomatosis and blindness [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1973 The clinical syndrome of meningeal carcinomatosis includes headache, dementia, radiculopathy, and cranial nerve palsies. Blindness may be the first, or most prominent, symptom. When blindness occurs in adult life, meningeal carcinomatosis should be included in the differential diagnosis, even in the absence of other symptoms and in the absence of known
P H, Altrocchi, P B, Eckman
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Hypoglycorrhachia in meningeal carcinomatosis [PDF]
Cancer, 1966 A case of malignant melanoma with diffuse meningeal carcinomatosis and hypoglycorrhachia is presented. The combination of low spinal fluid glucose and bizarre or unexplained neurologic signs should bring to mind meningeal carcinomatosis. In the presence of known malignant disease and fever hypoglycorrhachia should stimulate a diligent search of the ...
V T, De Vita, G P, Canellos
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Adenocarcinoma lung presenting with meningeal carcinomatosis
Monaldi Archives for Chest Disease, 2021 Meningeal infiltration by malignant metastasis process without brain parenchymal involvement is very unusual event in patients with bronchogenic carcinoma.
Ramakant Dixit +3 more
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Clinical characteristics of 23 cases of meningeal carcinomatosis
Chinese Journal of Contemporary Neurology and Neurosurgery, 2019 Objective To investigate the clinical characteristics of meningeal carcinomatosis with nervous system syndrome as initial symptom. Methods Clinical data, laboratory and imageing examinations were retrospectively analyzed in 23 patients of meningeal ...
Bo LI +8 more
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