Results 1 to 10 of about 115,799 (305)

Meninges harbor cells expressing neural precursor markers during development and adulthood [PDF]

Frontiers in Cellular Neuroscience, 2015
Brain and skull developments are tightly synchronized, allowing the cranial bones to dynamically adapt to the brain shape. At the brain-skull interface, meninges produce the trophic signals necessary for normal corticogenesis and bone development ...
Francesco Bifari, Annachiara Pino, Giorgio Malpeli   +2 more
exaly   +5 more sources

Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability [PDF]

eLife
The meninges, which envelop and protect the brain, host a dense network of resident macrophages with diverse roles in regulating homeostasis and neuroinflammation. Despite their importance, we have a limited understanding of their behavior in vivo.
Simone Carneiro-Nascimento, Chao Wei, Anna Gutterman, Dan Levy   +3 more
doaj   +2 more sources

Mechanical Characterization and Modeling of the Porcine Cerebral Meninges

Frontiers in Bioengineering and Biotechnology, 2020
The cerebral meninges, made up of the dura, arachnoid, and pia mater, is a tri-layer membrane that surrounds the brain and the spinal cord and has an important function in protecting the brain from injury.
Baptiste Pierrat, Baptiste Pierrat, Louise Carroll, Florence Merle, David B. MacManus, David B. MacManus, Robert Gaul, Caitríona Lally, Michael D. Gilchrist, Aisling Ní Annaidh, Aisling Ní Annaidh   +10 more
doaj   +3 more sources

Flow cytometry and immunohistochemistry of the mouse dural meninges for immunological and virological assessments

STAR Protocols, 2023
Summary: The highly vascularized meninges protect the surface of the central nervous system and contain a dense network of immune cells controlling neuroinfection and neuroinflammation.
Annie Roussel-Queval, Julie Rebejac, Elisa Eme-Scolan, Laurie Arnaud Paroutaud, Rejane Rua   +4 more
doaj   +2 more sources

T cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges. [PDF]

J Clin Invest
Infiltration of T cell acute lymphoblastic leukemia (T-ALL) into the meninges worsens prognosis, underscoring the need to understand mechanisms driving meningeal involvement.
Sharma ND, Keewan E, Ornatowski W, Paul S, Nysus M, Barnett CC, Wolfson J, Jacquez Q, Myers BL, Kang H, Zychowski KE, Winter SS, Loh ML, Hunger SP, Castillo EF, Taghon T, Halsey C, Vue TY, Jones N, Ntziachristos P, Matlawska-Wasowska K.   +20 more
europepmc   +3 more sources

Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions [PDF]

Purinergic Signalling, 2016
© 2016, Springer Science+Business Media Dordrecht.Extracellular ATP is suspected to contribute to migraine pain but regulatory mechanisms controlling pro-nociceptive purinergic mechanisms in the meninges remain unknown.
Gennady G Yegutkin, Cindy Guerrero-Toro, Erkan Kilinc   +2 more
exaly   +1 more source

Clinical, anatomopathological and immunohistochemical findings of a transitional cell carcinoma from nasal cavity, frontal and ethmoidal sinus with meningoencephalic invasion in a dog [PDF]

Open Veterinary Journal, 2021
Background: Primary neoplasms of the nasal cavity and sinuses are uncommon in domestic animals, most of which are of epithelial origin, being adenocarcinoma the most common tumor diagnosed in this region.
Leonardo L. Gorza, Ayisa R. Oliveira, Maryleydy G. Porto, Vania C. Santos, Isabela Hardt, Luciana F.P. Maestri, Tayse D. Souza, Mayra C. Flecher   +7 more
doaj   +1 more source

Morphometrics of the Spinal Cord and Surrounding Structures in Alligator mississippiensis

Biology, 2022
Understanding the fluid dynamics of the cerebrospinal fluid requires a quantitative description of the spaces in which it flows, including the spinal cord and surrounding meninges. The morphometrics of the spinal cord and surrounding tissues were studied
Skye Greer, Michael J. Cramberg, Bruce A. Young   +2 more
doaj   +1 more source

The meningeal transcriptional response to traumatic brain injury and aging

eLife, 2023
Emerging evidence suggests that the meningeal compartment plays instrumental roles in various neurological disorders, however, we still lack fundamental knowledge about meningeal biology.
Ashley C Bolte, Daniel A Shapiro, Arun B Dutta, Wei Feng Ma, Katherine R Bruch, Michael A Kovacs, Ana Royo Marco, Hannah E Ennerfelt, John R Lukens   +8 more
doaj   +1 more source

Antidromic Spike Propagation and Dissimilar Expression of P2X, 5-HT, and TRPV1 Channels in Peripheral vs. Central Sensory Axons in Meninges

Frontiers in Cellular Neuroscience, 2021
Background: The terminal branches of the trigeminal nerve in meninges are supposed to be the origin site of migraine pain. The main function of these peripheral sensory axons is the initiation and propagation of spikes in the orthodromic direction to the
Oleg Gafurov, Kseniia Koroleva, Kseniia Koroleva, Rashid Giniatullin, Rashid Giniatullin   +4 more
doaj   +1 more source