Results 1 to 10 of about 122,319 (302)

Meninges Harbor Cells Expressing Neural Precursor Markers During Development and Adulthood [PDF]

Frontiers in Cellular Neuroscience, 2015
Brain and skull developments are tightly synchronized, allowing the cranial bones to dynamically adapt to the brain shape. At the brain-skull interface, meninges produce the trophic signals necessary for normal corticogenesis and bone development ...
Giorgio Malpeli, Annachiara Pino, Ilaria Decimo   +2 more
exaly   +6 more sources

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression [PDF]

Advanced Science
Patients with Alzheimer's disease (AD) often develop osteoporosis, but the role of bone remodeling in AD remains unclear. We previously showed that osteoblast‐specific expression of APPswe induces bone loss, glial activation, and behavioral deficits ...
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
doaj   +2 more sources

Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability [PDF]

eLife
The meninges, which envelop and protect the brain, host a dense network of resident macrophages with diverse roles in regulating homeostasis and neuroinflammation. Despite their importance, we have a limited understanding of their behavior in vivo.
Simone Carneiro-Nascimento, Chao Wei, Anna Gutterman, Dan Levy   +3 more
doaj   +2 more sources

Effects of Sound Interventions on the Permeability of the Blood–Brain Barrier and Meningeal Lymphatic Clearance

Brain Sciences, 2022
The meningeal lymphatic, or glymphatic, system is receiving increasing attention from the scientific community. Recent work includes noninvasive techniques to demonstrate relationships between blood–brain barrier (BBB) activity and the glymphatic system ...
Sean Sachdeva, Sushmita Persaud, Milani Patel, Peyton Popard, Aaron Colverson, Sylvain Doré   +5 more
doaj   +1 more source

Translationally Relevant Magnetic Resonance Imaging Markers in a Ferret Model of Closed Head Injury

Frontiers in Neuroscience, 2022
Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models are ...
Elizabeth B. Hutchinson, Anakaren Romero-Lozano, Hannah R. Johnson, Andrew K. Knutsen, Andrew K. Knutsen, Asamoah Bosomtwi, Asamoah Bosomtwi, Alexandru Korotcov, Alexandru Korotcov, Anandakumar Shunmugavel, Anandakumar Shunmugavel, Sarah G. King, Susan C. Schwerin, Susan C. Schwerin, Sharon L. Juliano, Sharon L. Juliano, Bernard J. Dardzinski, Bernard J. Dardzinski, Carlo Pierpaoli   +18 more
doaj   +1 more source

Preliminary study on double ⁃ dose icotinib successfully treated leptomeningeal metastasis in lung adenocarcinoma patient with EGFR gene sensitive mutation

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To report the diagnosis and treatment of a patient with meningeal metastases from lung adenocarcinoma, and explore the significance of cerebrospinal fluid (CSF) gene detection for clinical treatment and the efficacy and safety of double⁃dose ...
LIU Mei, MU Ning, MA Chun⁃hua, LI Jin⁃duo, LI Lin, JIANG Rong   +5 more
doaj   +1 more source

Clinical, anatomopathological and immunohistochemical findings of a transitional cell carcinoma from nasal cavity, frontal and ethmoidal sinus with meningoencephalic invasion in a dog [PDF]

Open Veterinary Journal, 2021
Background: Primary neoplasms of the nasal cavity and sinuses are uncommon in domestic animals, most of which are of epithelial origin, being adenocarcinoma the most common tumor diagnosed in this region.
Leonardo L. Gorza, Ayisa R. Oliveira, Maryleydy G. Porto, Vania C. Santos, Isabela Hardt, Luciana F.P. Maestri, Tayse D. Souza, Mayra C. Flecher   +7 more
doaj   +1 more source

Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System

Frontiers in Immunology, 2021
The central nervous system (CNS) parenchyma is enclosed and protected by a multilayered system of cellular and acellular barriers, functionally separating glia and neurons from peripheral circulation and blood-borne immune cells. Populating these borders
Daniela C. Ivan, Sabrina Walthert, Kristina Berve, Jasmin Steudler, Giuseppe Locatelli   +4 more
doaj   +1 more source

Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges

Cells, 2021
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj   +1 more source

Morphometrics of the Spinal Cord and Surrounding Structures in Alligator mississippiensis

Biology, 2022
Understanding the fluid dynamics of the cerebrospinal fluid requires a quantitative description of the spaces in which it flows, including the spinal cord and surrounding meninges. The morphometrics of the spinal cord and surrounding tissues were studied
Skye Greer, Michael J. Cramberg, Bruce A. Young   +2 more
doaj   +1 more source