A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression [PDF]
Advanced SciencePatients with Alzheimer's disease (AD) often develop osteoporosis, but the role of bone remodeling in AD remains unclear. We previously showed that osteoblast‐specific expression of APPswe induces bone loss, glial activation, and behavioral deficits ...
Lei Xiong +6 more
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Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges
Cells, 2021 The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Stefan Schulte-Merker
exaly +3 more sources
Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability [PDF]
eLifeThe meninges, which envelop and protect the brain, host a dense network of resident macrophages with diverse roles in regulating homeostasis and neuroinflammation. Despite their importance, we have a limited understanding of their behavior in vivo.
Simone Carneiro-Nascimento +3 more
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Mechanical Characterization and Modeling of the Porcine Cerebral Meninges
Frontiers in Bioengineering and Biotechnology, 2020 The cerebral meninges, made up of the dura, arachnoid, and pia mater, is a tri-layer membrane that surrounds the brain and the spinal cord and has an important function in protecting the brain from injury.
Robert Gaul +2 more
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Living on the Edge of the CNS: Meninges Cell Diversity in Health and Disease
Frontiers in Cellular Neuroscience, 2021 The meninges are the fibrous covering of the central nervous system (CNS) which contain vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia).
Hannah E Jones, Julia Derk
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Rare Tumors, 2010 Meningeal fibrosarcomas are rare tumors. Only 41 cases have been reported in the literature to date. Primary central nervous system fibrosarcomas are very aggressive neoplasms and have a poor prognosis. Hence they need to be correctly diagnosed.
exaly +3 more sources
Clinical, anatomopathological and immunohistochemical findings of a transitional cell carcinoma from nasal cavity, frontal and ethmoidal sinus with meningoencephalic invasion in a dog [PDF]
Open Veterinary Journal, 2021 Background: Primary neoplasms of the nasal cavity and sinuses are uncommon in domestic animals, most of which are of epithelial origin, being adenocarcinoma the most common tumor diagnosed in this region.
Leonardo L. Gorza +7 more
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Morphometrics of the Spinal Cord and Surrounding Structures in Alligator mississippiensis
Biology, 2022 Understanding the fluid dynamics of the cerebrospinal fluid requires a quantitative description of the spaces in which it flows, including the spinal cord and surrounding meninges. The morphometrics of the spinal cord and surrounding tissues were studied
Skye Greer +2 more
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The meningeal transcriptional response to traumatic brain injury and aging
eLife, 2023 Emerging evidence suggests that the meningeal compartment plays instrumental roles in various neurological disorders, however, we still lack fundamental knowledge about meningeal biology.
Ashley C Bolte +8 more
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Frontiers in Cellular Neuroscience, 2021 Background: The terminal branches of the trigeminal nerve in meninges are supposed to be the origin site of migraine pain. The main function of these peripheral sensory axons is the initiation and propagation of spikes in the orthodromic direction to the
Oleg Gafurov +4 more
doaj +1 more source