Results 31 to 40 of about 115,799 (305)
CNS-Draining Meningeal Lymphatic Vasculature: Roles, Conundrums and Future Challenges
Frontiers in Pharmacology, 2021 A genuine and functional lymphatic vascular system is found in the meninges that sheath the central nervous system (CNS). This unexpected (re)discovery led to a reevaluation of CNS fluid and solute drainage mechanisms, neuroimmune interactions and the ...
Sofia Pereira das Neves +2 more
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BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus
Stem Cell Reports, 2017 BACE1 is validated as Alzheimer's β-secretase and a therapeutic target for Alzheimer's disease. In examining BACE1-null mice, we discovered that BACE1 deficiency develops abnormal clusters of immature neurons, forming doublecortin-positive neuroblasts ...
Hailong Hou +5 more
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The Journal of Nervous and Mental Disease, 1919 n ...
Royster, L. T., McDowell, W. P.
openaire +1 more source
Nanomaterials, 2014 Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou +5 more
doaj +1 more source
Dural Immune Cells, CGRP, and Migraine
Frontiers in Neurology, 2022 Migraine is the most common neurological disorder in the world, affecting 12% of the population. Migraine involves the central nervous system, trigeminal nerves and meninges. Recent advances have shown that targeting calcitonin gene-related peptide (CGRP)
Louis K. Balcziak +4 more
doaj +1 more source
Entry, dispersion and differentiation of microglia in the developing central nervous system
Anais da Academia Brasileira de Ciências, 2000 Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream.
JULIO NAVASCUÉS +3 more
doaj +1 more source
Case Report: Primary Diffuse Leptomeningeal Oligodendrogliomatosis in a Young Adult Cat
Frontiers in Veterinary Science, 2021 A 2-year-old cat was presented with progressive ataxia. Despite treatment the animal died. Pathomorphological examination revealed a widespread leptomeningeal mass at all levels of the central nervous system accentuated on the cervical spinal cord and ...
Elisa Chludzinski +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu +8 more
wiley +1 more source
Unconventional T cells in brain homeostasis, injury and neurodegeneration
Frontiers in Immunology, 2023 The interaction between peripheral immune cells and the brain is an important component of the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells, mucosal-associated invariant T (MAIT) cells, γδ T cells, and other poorly
Mengfei Lv +4 more
doaj +1 more source
Anatomy of the Spinal Meninges
, 2016 International audienceBackground: The spinal meninges have received less attention than the cranial meninges in the literature, although several points remain debatable and poorly understood, like their phylogenesis, their development, and their ...
Sakka, Laurent +2 more
core +1 more source