Results 31 to 40 of about 120,973 (211)
CNS-Draining Meningeal Lymphatic Vasculature: Roles, Conundrums and Future Challenges
Frontiers in Pharmacology, 2021 A genuine and functional lymphatic vascular system is found in the meninges that sheath the central nervous system (CNS). This unexpected (re)discovery led to a reevaluation of CNS fluid and solute drainage mechanisms, neuroimmune interactions and the ...
Sofia Pereira das Neves +2 more
doaj +1 more source
BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus
Stem Cell Reports, 2017 BACE1 is validated as Alzheimer's β-secretase and a therapeutic target for Alzheimer's disease. In examining BACE1-null mice, we discovered that BACE1 deficiency develops abnormal clusters of immature neurons, forming doublecortin-positive neuroblasts ...
Hailong Hou +5 more
doaj +1 more source
Nanomaterials, 2014 Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou +5 more
doaj +1 more source
Entry, dispersion and differentiation of microglia in the developing central nervous system
Anais da Academia Brasileira de Ciências, 2000 Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream.
JULIO NAVASCUÉS +3 more
doaj +1 more source
Dural Immune Cells, CGRP, and Migraine
Frontiers in Neurology, 2022 Migraine is the most common neurological disorder in the world, affecting 12% of the population. Migraine involves the central nervous system, trigeminal nerves and meninges. Recent advances have shown that targeting calcitonin gene-related peptide (CGRP)
Louis K. Balcziak +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong +10 more
wiley +1 more source
Case Report: Primary Diffuse Leptomeningeal Oligodendrogliomatosis in a Young Adult Cat
Frontiers in Veterinary Science, 2021 A 2-year-old cat was presented with progressive ataxia. Despite treatment the animal died. Pathomorphological examination revealed a widespread leptomeningeal mass at all levels of the central nervous system accentuated on the cervical spinal cord and ...
Elisa Chludzinski +3 more
doaj +1 more source
The Journal of Nervous and Mental Disease, 1919 n ...
Royster, L. T., McDowell, W. P.
openaire +1 more source
Advanced Materials, EarlyView.This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà +15 more
wiley +1 more source
Unconventional T cells in brain homeostasis, injury and neurodegeneration
Frontiers in Immunology, 2023 The interaction between peripheral immune cells and the brain is an important component of the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells, mucosal-associated invariant T (MAIT) cells, γδ T cells, and other poorly
Mengfei Lv +4 more
doaj +1 more source