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Meninges: from protective membrane to stem cell niche [PDF]
Meninges are a three tissue membrane primarily known as coverings of the brain. More in depth studies on meningeal function and ultrastructure have recently changed the view of meninges as a merely protective membrane.
G. Fumagalli +4 more
core +3 more sources
BackgroundParasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches.
Rashid Giniatullin +9 more
doaj +1 more source
A neoplasm associated with the meninges of the spinal canal – a case report
Introduction: Spinal canal neoplasms are a heterogeneous group of diseases including both primary and metastatic tumors, either benign or malignant. These tumors can develop both intraspinally and peripherally.
Marcin Kulczyński +3 more
doaj +3 more sources
TRP Channels and Migraine: Recent Developments and New Therapeutic Opportunities
Migraine is the second-most disabling disease worldwide, and the second most common neurological disorder. Attacks can last many hours or days, and consist of multiple symptoms including headache, nausea, vomiting, hypersensitivity to stimuli such as ...
Silvia Benemei, Greg Dussor
doaj +1 more source
Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System
The central nervous system (CNS) parenchyma is enclosed and protected by a multilayered system of cellular and acellular barriers, functionally separating glia and neurons from peripheral circulation and blood-borne immune cells. Populating these borders
Daniela C. Ivan +4 more
doaj +1 more source
Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition characterized by mechanical hypersensitivity. We previously identified microglial activation via release of colony-stimulating factor 1 (CSF1) from injured sensory ...
Julia A Kuhn +10 more
doaj +1 more source
IntroductionInvasion of the central nervous system (CNS) is the most serious consequence of Trypanosoma brucei infection, which causes sleeping sickness.
Nestor L. Uzcategui +9 more
doaj +1 more source
Meninges: A Widespread Niche of Neural Progenitors for the Brain [PDF]
Emerging evidence highlights the several roles that meninges play in relevant brain functions as they are a protective membrane for the brain, produce and release several trophic factors important for neural cell migration and survival, control ...
Decimo, Ilaria +11 more
core +1 more source
Neural tube-associated boundary caps are a major source of mural cells in the skin
In addition to their roles in protecting nerves and increasing conduction velocity, peripheral glia plays key functions in blood vessel development by secreting molecules governing arteries alignment and maturation with nerves. Here, we show in mice that
Gaspard Gerschenfeld +10 more
doaj +1 more source

