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A neoplasm associated with the meninges of the spinal canal – a case report
Introduction: Spinal canal neoplasms are a heterogeneous group of diseases including both primary and metastatic tumors, either benign or malignant. These tumors can develop both intraspinally and peripherally.
Marcin Kulczyński +3 more
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TRP Channels and Migraine: Recent Developments and New Therapeutic Opportunities
Migraine is the second-most disabling disease worldwide, and the second most common neurological disorder. Attacks can last many hours or days, and consist of multiple symptoms including headache, nausea, vomiting, hypersensitivity to stimuli such as ...
Silvia Benemei, Greg Dussor
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Dwellers and Trespassers: Mononuclear Phagocytes at the Borders of the Central Nervous System
The central nervous system (CNS) parenchyma is enclosed and protected by a multilayered system of cellular and acellular barriers, functionally separating glia and neurons from peripheral circulation and blood-borne immune cells. Populating these borders
Daniela C. Ivan +4 more
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Meninges: A Widespread Niche of Neural Progenitors for the Brain [PDF]
Emerging evidence highlights the several roles that meninges play in relevant brain functions as they are a protective membrane for the brain, produce and release several trophic factors important for neural cell migration and survival, control ...
Decimo, Ilaria +11 more
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Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
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Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition characterized by mechanical hypersensitivity. We previously identified microglial activation via release of colony-stimulating factor 1 (CSF1) from injured sensory ...
Julia A Kuhn +10 more
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IntroductionInvasion of the central nervous system (CNS) is the most serious consequence of Trypanosoma brucei infection, which causes sleeping sickness.
Nestor L. Uzcategui +9 more
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Neural tube-associated boundary caps are a major source of mural cells in the skin
In addition to their roles in protecting nerves and increasing conduction velocity, peripheral glia plays key functions in blood vessel development by secreting molecules governing arteries alignment and maturation with nerves. Here, we show in mice that
Gaspard Gerschenfeld +10 more
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Meningeal fibrosarcomas are rare tumors. Only 41 cases have been reported in the literature to date. Primary central nervous system fibrosarcomas are very aggressive neoplasms and have a poor prognosis. Hence they need to be correctly diagnosed.
Ishwar Chand Premsagar +2 more
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