Results 21 to 30 of about 112,287 (262)
Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges
Cells, 2021 The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
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Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
eLife, 2021 Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition characterized by mechanical hypersensitivity. We previously identified microglial activation via release of colony-stimulating factor 1 (CSF1) from injured sensory ...
Julia A Kuhn +10 more
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Frontiers in Immunology, 2023 IntroductionInvasion of the central nervous system (CNS) is the most serious consequence of Trypanosoma brucei infection, which causes sleeping sickness.
Nestor L. Uzcategui +9 more
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Neural tube-associated boundary caps are a major source of mural cells in the skin
eLife, 2023 In addition to their roles in protecting nerves and increasing conduction velocity, peripheral glia plays key functions in blood vessel development by secreting molecules governing arteries alignment and maturation with nerves. Here, we show in mice that
Gaspard Gerschenfeld +10 more
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CNS-Draining Meningeal Lymphatic Vasculature: Roles, Conundrums and Future Challenges
Frontiers in Pharmacology, 2021 A genuine and functional lymphatic vascular system is found in the meninges that sheath the central nervous system (CNS). This unexpected (re)discovery led to a reevaluation of CNS fluid and solute drainage mechanisms, neuroimmune interactions and the ...
Sofia Pereira das Neves +2 more
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The Journal of Nervous and Mental Disease, 1919 n ...
Royster, L. T., McDowell, W. P.
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BACE1 Deficiency Causes Abnormal Neuronal Clustering in the Dentate Gyrus
Stem Cell Reports, 2017 BACE1 is validated as Alzheimer's β-secretase and a therapeutic target for Alzheimer's disease. In examining BACE1-null mice, we discovered that BACE1 deficiency develops abnormal clusters of immature neurons, forming doublecortin-positive neuroblasts ...
Hailong Hou +5 more
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Mechanical Characterization and Modeling of the Porcine Cerebral Meninges
Frontiers in Bioengineering and Biotechnology, 2020 The cerebral meninges, made up of the dura, arachnoid, and pia mater, is a tri-layer membrane that surrounds the brain and the spinal cord and has an important function in protecting the brain from injury.
Baptiste Pierrat +10 more
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Nanomaterials, 2014 Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre ...
Iraklis Papageorgiou +5 more
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