Results 61 to 70 of about 3,970 (233)

Blindness due to leptomeningeal carcinomatosis as an initial manifestation of recurrent acute lymphoblastic leukemia

Taiwan Journal of Ophthalmology, 2019
Leptomeningeal carcinomatosis (LC) is an uncommon presentation of acute lymphoblastic leukemia (ALL), and it is a devastating and life-threatening complication.
Ya-Chi Huang, Cyuan-Jheng Wang, Jieh-Ren Jou   +2 more
doaj   +1 more source

Multiple myeloma invasion of the central nervous system [PDF]

, 2012
Introduction. Multiple myeloma (MM) is characterized by the presence of neoplastic proliferating plasma cells. The tumor is generally restricted to the bone marrow.
Marjanović Slobodan, Mađaru Lavinika, Mijušković Zoran, Radović Vesna, Ralić Tijana, Stamatović Dragana, Stojanović Jelica, Trimčev Jovana   +7 more
core   +1 more source

Patients with chronic post‐dural puncture headache do not have typical imaging features of intracranial hypotension: An MRI study using the Bern score

Headache: The Journal of Head and Face Pain, Volume 66, Issue 1, Page 193-201, January 2026.
Abstract Objective This study evaluated cranial magnetic resonance imaging (MRI) signs in patients with post‐dural puncture headache (PDPH) using an established assessment score developed for spontaneous intracranial hypotension (Bern score). We hypothesize that patients with chronic PDPH do not have typical imaging features of intracranial hypotension.
Charlotte Zander, Christian Fung, Amir El Rahal, Florian Volz, Katharina Wolf, Alexander Rau, Hansjörg Mast, Jürgen Beck, Horst Urbach, Niklas Lützen   +9 more
wiley   +1 more source

Rapid symptomatic relief of HER2-positive gastric cancer leptomeningeal carcinomatosis with lapatinib, trastuzumab and capecitabine: a case report

BMC Cancer, 2018
Background Gastric cancer patients with widespread metastasis, especially meningeal metastases, have an extremely prognosis and limited therapeutic choices.
Xiao-Dong Jiao, Chunming Ding, Yuan-Sheng Zang, Guanzhen Yu   +3 more
doaj   +1 more source

Brain metastases in gastro-oesophageal adenocarcinoma: Insights into the role of the human epidermal growth factor receptor 2 (HER2) [PDF]

, 2015
Background: Gastro-oesophageal adenocarcinomas rarely metastasize to the central nervous system (CNS). The role of the human epidermal growth factor receptor 2 (HER2) in patients with these cancers and CNS involvement is presently unknown.Patients and ...
A Cats, A Kafka, A Knuth, A Musolino, A Trip, B Schuknecht, BC Pestalozzi, C Bozzetti, C Gravalos, D Wagner, E Van Cutsem, FT Bosman, G Corso, H Grabsch, H I Grabsch, H Moch, H Shoji, HS Lee, J Diebold, J Feilchenfeldt, J Rüschoff, JE York, K Khanfir, M D'Angelica, M Hofmann, M Preusser, M Siano, O Balague, P Giglio, P Gut, P Laurén, PH Go, PL Kunz, PW Sperduto, R Kushima, R Shibata, R Wadhwa, S Aebi, S Hofer, T Abu Hejleh, T Hamaguchi, U Held, VS Warneke, VS Warneke, W Jochum, WB Al-Refaie, Y Maehara, Y Shimada, Y Uchikado, YJ Bang, YY Choi, YY Janjigian, Z Varga, Z Varga   +53 more
core   +7 more sources

Guidelines for the Diagnosis and Treatment of Advanced Breast Cancer in China (2024 Edition)

Cancer Innovation, Volume 4, Issue 6, December 2025.
“The core objective of this guideline is to personalize the management of advanced breast cancer through molecular subtyping, optimizing the balance between survival and quality of life. We integrate recent evidence‐based advances and underscore the essential roles of multidisciplinary collaboration and management of patient‐reported outcomes (PROs ...
Breast Cancer Expert Committee of the National Quality Control Center for Cancer, Breast Cancer Expert Committee of the China Anti‐Cancer Association, Cancer Drug Clinical Research Committee of the China Anti‐Cancer Association   +2 more
wiley   +1 more source

Carcinomatous meningitis in non-small cell lung cancer: Palliation with intrathecal treatment

Indian Journal of Medical and Paediatric Oncology, 2014
Carcinomatous meningitis or meningeal carcinomatosis is seen in up to 5% of patients of metastatic non-small cell lung cancer. However, isolated carcinomatous meningitis without brain parenchymal metastasis is less common.
D. Santhosh Kumar, Vanita Noronha, Amit Joshi, Hasmukh Jain, Kumar Prabhash   +4 more
doaj   +1 more source

Upfront stereotactic radiosurgery in patients with brain metastases from small cell lung cancer: retrospective analysis of 41 patients [PDF]

, 2014
BACKGROUND: Although the efficacy of prophylactic or therapeutic whole brain radiotherapy (WBRT) for brain metastases (BM) from small cell lung cancer (SCLC) is well established, the role of stereotactic radiosurgery (SRS) has yet to be determined.
Motohiro Hayashi, Shoji Yomo
core   +1 more source

The Value of Oligoclonal Bands in Multiple Sclerosis Compared to Other Neurological Disorders: A Retrospective Data Analysis From an Austrian Tertiary Center

European Journal of Neurology, Volume 32, Issue 12, December 2025.
ABSTRACT Background Cerebrospinal fluid (CSF) analysis is key to diagnosing multiple sclerosis (MS). In particular, the presence of CSF‐specific oligoclonal bands (OCB) is examined alongside differential diagnostic aspects. This study aims to investigate the diagnostic value of OCB in MS compared to other neurological disorders.
Tobias Monschein, Benjamin Scheicher, Markus Ponleitner, Nik Krajnc, Fabian Föttinger, Tobias Zrzavy, Paulus Rommer, Barbara Kornek, Gabriel Bsteh, Thomas Perkmann, Thomas Berger, Fritz Leutmezer   +11 more
wiley   +1 more source

Managing hydrocephalus in patients with leptomeningeal disease: A multicenter retrospective analysis

International Journal of Cancer, Volume 157, Issue 8, Page 1613-1624, 15 October 2025.
What's New? Leptomeningeal disease is a highly palliative condition of tumor cell seeding that can cause symptomatic hydrocephalus. This multi‐center retrospective study of patients with leptomeningeal disease‐associated hydrocephalus compared the placement of ventriculoperitoneal shunts and Rickham reservoirs for cerebrospinal fluid drainage.
Obada T. Alhalabi, Lukas Klein, David Wasilewski, Amine Mellal, Carmen Büsken, Clara Buszello, Giulia Cossu, Ilker Y. Eyüpoglu, Andreas W. Unterberg, Peter Vajkoczy, Gabriele Schackert, Mahmoud Messerer, Martin Misch, Tobias Kessler, Wolfgang Wick, Christine Jungk, Ahmed El Damaty, Sandro M. Krieg, Tareq A. Juratli, Alexander Younsi   +19 more
wiley   +1 more source