Results 121 to 130 of about 43,022 (268)
High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor
We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji +11 more
wiley +1 more source
Migraine Features in Patients With Sudden Sensorineural Hearing Loss
Abstract Objective To investigate the prevalence of migraine features among patients with sudden sensorineural hearing loss (SSNHL) and evaluate potential clinical associations. Study Design Retrospective survey‐based study. Setting Single institution tertiary care center. Methods 168 adult patients with SSNHL were recruited.
Yalda Yazdani +5 more
wiley +1 more source
Surgical treatment of an intracranial Cryptococcus granuloma in a cat
Summary A 4‐year‐old, female, neutered, domestic short‐haired cat presented with an acute onset of progressive compulsive pacing and obtundation. General physical examination revealed a crusty nasal discharge, with neurological examination showing a forebrain localisation.
Guido Bertoldi +4 more
wiley +1 more source
MRI findings in a dog with calvarial squamous cell carcinoma
Journal of Small Animal Practice, EarlyView.
P. Sebestyén +4 more
wiley +1 more source
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan +3 more
wiley +1 more source
Why Is MS a More Frequent Complication of EBV Infection in Females?
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
Tuberculous meningitis causing holocord longitudinally extensive transverse myelitis
Longitudinally extensive transverse myelitis (LETM) is a neurological entity with characteristic inflammatory lesions in ≥3 vertebral segments of the spinal cord. It is most commonly associated with neuromyelitis optica spectrum disorder.
Nishanth Dev +3 more
doaj +1 more source
Metastases in Meckel's Cave: A Challenge of Differential Diagnosis [PDF]
Metastases in Meckel's cave are a rare tumor entity and should be considered as important differential diagnosis, especially if the patient presents with trigeminal neuralgia and suffers from a known primary malignancy. We present three cases of patients
Kollias, Spyros +4 more
core
ABSTRACT The dural tail sign (DTS) is an imaging sign used to categorize intracranial masses based on magnetic resonance imaging (MRI) axial localization. It is common in masses arising from outside the neuroparenchyma (extra‐axial) and rare in masses arising from the neuroparenchyma (intra‐axial).
John F. Griffin IV +9 more
wiley +1 more source
Porous polyethylene in reconstructive head and neck surgery [PDF]
Berghaus, Alexander
core +1 more source

