Results 131 to 140 of about 41,282 (249)

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte‐mediated etiology of epileptic cortical thinning

open access: yesEpilepsia Open, Volume 11, Issue 3, Page 895-911, June 2026.
Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang   +9 more
wiley   +1 more source

A 50‐year‐old man with a 12‐year history of extensive pachymeningeal thickening

open access: yes
Brain Pathology, Volume 36, Issue 4, July 2026.
Alyssa M. Lee   +3 more
wiley   +1 more source

RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling

open access: yesGlia, Volume 74, Issue 6, June 2026.
Using pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Vito Antonio Baldassarro   +4 more
wiley   +1 more source

Diagnostic challenges in hemangioblastoma: lessons from a rare case presentation

open access: yesEgyptian Journal of Neurosurgery
Background Hemangioblastomas are rare, slow-growing benign neoplasms predominantly affecting the central nervous system (CNS). Despite their benign nature, they pose diagnostic challenges due to their diverse clinical manifestations and radiological ...
Jayeshkumar Kanani
doaj   +1 more source

Feline malignant lymphoma in an uncommon location as a differential diagnosis for neurological disease

open access: yesJournal of Feline Medicine and Surgery Open Reports
Case summary A 12-year-old male castrated domestic shorthair cat exhibited right Horner’s syndrome, right facial nerve paresis, difficulty swallowing, coughing, gait abnormalities and weight loss.
Maximilien Lépine   +3 more
doaj   +1 more source

Metastização Leptomeníngea de Origem Ginecológica: O Papel Decisivo da Citologia

open access: yes
Cytopathological examination of cerebrospinal fluid is an essential diagnostic method in the evaluation of central nervous system disorders and plays a fundamental role in the detection of meningeal dissemination by neoplasms.
Dias, Cristiana
core   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu   +9 more
wiley   +1 more source

Perinatal White Matter Injury: Connecting Histology, Pathophysiology and Neurodevelopmental Outcomes

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Perinatal white matter injury is associated with high rates of adverse neuropsychiatric outcomes and millions of years lived with disability. This review focuses on the macroscopic and microscopic features of perinatal white matter injury and how these relate to the proposed pathophysiology of this disease and adverse neurodevelopmental outcomes ...
Angela N. Viaene
wiley   +1 more source

IL‐25 Enhances Eosinophil‐Associated Inflammation in Angiostrongylus cantonensis‐Infected Mice

open access: yesParasite Immunology, Volume 48, Issue 6, June 2026.
ABSTRACT This study aimed to investigate the role of interleukin (IL)‐25 in the pathogenesis of angiostrongylosis. We used ICR mice as non‐permissive hosts, divided them into groups and experimentally infected them with infective larvae of the Angiostrongylus cantonensis.
Chih‐Cheng Chuang   +4 more
wiley   +1 more source

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