Results 161 to 170 of about 327,511 (299)

Primary Progressive Multiple Sclerosis: New Therapeutic Approaches

Neuropsychopharmacology Reports, Volume 45, Issue 3, September 2025.
Primary progressive MS affects 10%–15% of MS patients, causing irreversible neurological impairment. Drugs like ocrelizumab show promise, while high‐dose biotin, simvastatin, and coenzyme Q10 are under investigation. Gene therapy and stem cell treatments also show potential.
Morteza Rajabi, Sajjad Shafaeibajestan, Sevda Asadpour, Ghazal Alyari, Niloofar Taei, Moein Kohkalani, Ramin Raoufinia, Hamed Afarande, Ehsan Saburi   +8 more
wiley   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Visual outcome including visual field defects after treatment of paediatric optic pathway glioma: A nationwide cohort study

Acta Ophthalmologica, Volume 103, Issue 6, Page 662-673, September 2025.
Abstract Purpose To examine long‐term visual impairment and visual field examination (VF) after diverse treatments for paediatric optic pathway glioma (OPG), and to determine prognostic factors for long‐term severe visual impairment or blindness. Methods A nationwide retrospective cohort study (1995–2018) was performed on paediatric OPGs that received ...
C. A. M. Bennebroek, J. van Zwol, M. C. Montauban van Swijndregt, S. E. Loudon, A. L. W. Groot, N. J. C. Bauer, J. W. Pott, I. C. Notting, A. J. van Sorge, M. M. van Genderen, P. de Graaf, A. Y. N. Schouten‐van Meeteren, P. Saeed, G. L. Porro   +13 more
wiley   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, Volume 182, Issue 17, Page 3975-3989, September 2025.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source

Evaluation of immunofluorescence cytochemical staining and laser-scanning confocal microscopy in the diagnosis of meningeal carcinomatosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To explore the value of combination of immunofluorescence cytochemical staining (ICS) and laser-scanning confocal microscopy (LSCM) in the diagnosis of meningeal carcinomatosis. Methods ICS and LSCM were used to detect the cellular distribution
Chunyang DOU, Xuewen FAN, Ruofen WU, Haiqing ZHU, Guisheng CHEN, Fanyuan KONG   +5 more
doaj  

Case Report: Primary intracranial lymphoma and meningioma manifesting as a composite tumor in a cat. [PDF]

Front Vet Sci
Vezza CR, Southard TL, LeRoith T, Strandberg NJ, Fowler KM, Shinn RL, Rossmeisl JH, Parker RL.   +7 more
europepmc   +1 more source

19 SURVIVAL AND RECURRENCE OUTCOMES FOR PRIMARY MENINGEAL MELANOCYTIC NEOPLASMS OF THE CENTRAL NERVOUS SYSTEM IN A MULTICENTER COHORT

Kira Tosefsky, Alexander D. Rebchuk, Ryan Gensler, M. Mullarkey, N Alarifi, Eduardo M. Suero, Chetan Bettegowda, Andrew Gao, Gelareh Zadeh, Stephen Yip, Serge Makarenko   +10 more
openalex   +1 more source

Freiburg Neuropathology Case Conference: Gait Ataxia, Segmental Hypoesthesia, and Combined Incontinence in a 57-Years-Old Patient. [PDF]

Clin Neuroradiol
Miarka L, Taschner U, Rölz R, Prinz M, Urbach H, Erny D, Taschner CA.   +6 more
europepmc   +1 more source

Pre- and Post-operative Parameters among Patients Undergoing Pre-operative Embolization of Meningioma: a Tertiary Referral Center Experience. [PDF]

Acta Med Philipp
Sacdalan DRL, Ignacio OR, Ignacio GMG.
europepmc   +1 more source

Ultra-rapid meningeal metastasis in triple-negative breast cancer: A case report. [PDF]

Int J Surg Case Rep
Zhang N, Jiang S, Ma K, Gu L, Chen H, Zhou Z.   +5 more
europepmc   +1 more source