Results 91 to 100 of about 463,498 (239)

Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, IDH‐wildtype

Brain Pathology, Volume 35, Issue 4, July 2025.
The molecular profile of adult primary leptomeningeal gliomatosis closely aligned with that of adult‐type glioblastoma, IDH‐wildtype, CNS WHO grade 4. Abstract Adult primary leptomeningeal gliomatosis (PLG) is a rare, rapidly progressive and fatal disease characterized by prominent leptomeningeal infiltration by a glial tumor without an identifiable ...
Yi Zhu, Darin D. Carabenciov, Derek R. Johnson, Jorge A. Trejo‐Lopez, Aivi T. Nguyen, Aditya Raghunathan, Giuseppe Lanzino, Cristiane M. Ida, Cinthya J. Zepeda‐Mendoza, Surendra Dasari, Emilie Russler‐Germain, Sonika Dahiya, Martha Quezado, Kenneth Aldape, Caterina Giannini   +14 more
wiley   +1 more source

Tuberculosis treatment in a refugee and migrant population: 20 years of experience on the Thai-Burmese border. [PDF]

, 2010
Although tuberculosis (TB) is a curable disease, it remains a major global health problem and an important cause of morbidity and mortality among vulnerable populations, including refugees and ...
Bonnet, M, Camelique, O, Guerin, P J, Hewison, C, Hsa Thaw, K, Minetti, A, Pinoges, L, Swaddiwudhipong, W, Thi, S   +8 more
core   +1 more source

Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. [PDF]

, 2018
Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE.
Doty, Daniel J, Fujinami, Robert S, Grist, Jonathan J, Lane, Thomas E, Marro, Brett S, Skinner, Dominic D, Syage, Amber R, Worne, Colleen   +7 more
core   +1 more source

Follicle on the Roof: Tertiary Lymphoid Structures in Central Nervous System Autoimmunity

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Leptomeningeal tertiary lymphoid structures (TLS) have emerged as a relatively common pathological feature of autoimmune disease, including multiple sclerosis (MS) and particularly in people with progressive and nonremitting MS. These ectopic lymphoid aggregates, observed in the leptomeninges adjacent to so‐called “Type 3” sub‐pial cortical ...
Michelle Zuo, Angela A. Wang, Jennifer L. Gommerman   +2 more
wiley   +1 more source

Atypical Cerebral Manifestations of Disseminated Mycobacterium tuberculosis

Frontiers in Neurology, 2017
BackgroundWe investigated the patterns of cerebral manifestations in patients with underlying pulmonary or extrapulmonary tuberculosis or disseminated tuberculosis.Materials and methodsFrom January 2010 to September 2016, brain magnetic resonance imaging
Ji Hye Hwang, Kyung Mi Lee, Ji Eun Park, Hyug-Gi Kim, Eui Jong Kim, Woo Suk Choi, Na Rae Yang   +6 more
doaj   +1 more source

Anemia in tuberculosis cases: A biomarker of severity?

PLoS ONE, 2021
IntroductionAnemia is a common condition at tuberculosis diagnosis, and there is evidence that its prevalence is higher in patients with tuberculosis than in those infected with Mycobacterium tuberculosis and healthy controls.
Edson Beyker de Mendonça, Carolina AranaStanis Schmaltz, Flavia Marinho Sant'Anna, Alexandre Gomes Vizzoni, Daniela Palheiro Mendes-de-Almeida, Raquel de Vasconcellos Carvalhaes de Oliveira, Valeria Cavalcanti Rolla   +6 more
doaj   +1 more source

Bacterial Infections of the Central Nervous System [PDF]

, 2015
Purpose of Review:: Bacterial infections of the central nervous system are neurologic emergencies. Prompt recognition and treatment are essential not only to prevent mortality, but also to decrease neurologic sequelae.
Roos, Karen L.
core   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

A rare case of tuberculous meningitis with pancreatitis

Medical Journal of Dr. D.Y. Patil University, 2016
Tuberculous meningitis (TBM) is the most common form of central nervous system manifestation of tuberculosis. However, tuberculous pancreatitis is rarely reported. We present an 8-year-old female child with TBM who had intractable vomiting that persisted
Drishti Chandru Tolani, Ira Shah
doaj   +1 more source

Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. [PDF]

, 2019
BACKGROUND: Invasive fungal diseases (IFDs) remain important causes of morbidity and mortality. The consensus definitions of the Infectious Diseases Group of the European Organization for Research and Treatment of Cancer and the Mycoses Study Group have ...
Akan, H, Alexander, BD, Andes, D, Azoulay, E, Baddley, JW, Bassetti, M, Bialek, R, Bradsher, RW, Bretagne, S, Calandra, T, Caliendo, AM, Castagnola, E, Chen, SC, Clancy, CJ, Cruciani, M, Cuenca-Estrella, M, Decker, CF, Desai, SR, Donnelly, JP, Fisher, B, Groll, AH, Harrison, T, Heussel, CP, Jensen, HE, Kauffman, CA, Kibbler, CC, Kontoyiannis, DP, Kullberg, B-J, Lagrou, K, Lamoth, F, Lehrnbecher, T, Lockhart, SR, Loeffler, J, Lortholary, O, Maertens, J, Marchetti, O, Marr, KA, Masur, H, Meis, JF, Morrisey, CO, Nucci, M, Ostrosky-Zeichner, L, Pagano, L, Pappas, PG, Patterson, TF, Perfect, JR, Prokop, CS, Racil, Z, Roilides, E, Ruhnke, M, Shoham, S, Slavin, MA, Sorrell, TC, Steinbach, WJ, Stevens, DA, Thompson, GR, Vazquez, JA, Verweij, PE, Viscoli, C, Walsh, TJ, Warris, A, Wheat, LJ, White, PL, Wingard, JR, Zaoutis, TE   +64 more
core   +5 more sources