Results 81 to 90 of about 15,278 (260)

Immunosenescence: Molecular Mechanisms, Diseases, and Therapeutic Innovations

MedComm, Volume 6, Issue 12, December 2025.
Along with organismal aging or pathogenic processes especially tumor, multiple immune cell types exhibit those well‐established hallmarks of cellular senescent phenotype, mainly characterized by irreversible cell cycle arrest, metabolic disorder, and over production of SASP.
Ninghan Gong, Xiting Pan, Yusi Deng, Jiajia Che, Junhao Bao, Mengqi Wang, Chuan Xu, Xiaowei Liu, Ying Shi   +8 more
wiley   +1 more source

Atypical Cerebral Manifestations of Disseminated Mycobacterium tuberculosis

Frontiers in Neurology, 2017
BackgroundWe investigated the patterns of cerebral manifestations in patients with underlying pulmonary or extrapulmonary tuberculosis or disseminated tuberculosis.Materials and methodsFrom January 2010 to September 2016, brain magnetic resonance imaging
Ji Hye Hwang, Kyung Mi Lee, Ji Eun Park, Hyug-Gi Kim, Eui Jong Kim, Woo Suk Choi, Na Rae Yang   +6 more
doaj   +1 more source

Anemia in tuberculosis cases: A biomarker of severity?

PLoS ONE, 2021
IntroductionAnemia is a common condition at tuberculosis diagnosis, and there is evidence that its prevalence is higher in patients with tuberculosis than in those infected with Mycobacterium tuberculosis and healthy controls.
Edson Beyker de Mendonça, Carolina AranaStanis Schmaltz, Flavia Marinho Sant'Anna, Alexandre Gomes Vizzoni, Daniela Palheiro Mendes-de-Almeida, Raquel de Vasconcellos Carvalhaes de Oliveira, Valeria Cavalcanti Rolla   +6 more
doaj   +1 more source

Indications to hospital admission and isolation of children wish possibile or defined tuberculosis: systematic review and proposed recommendations for pediatric patients leaving in developed countries. [PDF]

, 2015
Tuberculosis (TB) is a re-emerging health problem in developed countries. This paper is part of large guidelines on the global management of TB in children, by a group of scientific societies.
Assante, Lr, Bocchino, Marialuisa, Esposito, S, Gabiano, C, Garazzino, S, Guarino, A., Lancella, L, Lo Vecchio, A, Raffaldi, I, Scotto, R, Villani, A   +10 more
core   +2 more sources

Clinical and Laboratory Predictors of Poor Neurological Outcomes Following Infectious Encephalitis: Systematic Review and Meta‐Analysis

European Journal of Neurology, Volume 32, Issue 12, December 2025.
Clinical and laboratory predictors of long‐term neurological outcomes after infectious encephalitis. ABSTRACT Background and Objectives Infectious encephalitis is a serious global health problem linked to high rates of mortality and morbidity. However, clinical and laboratory factors that impact neurological outcomes following infectious encephalitis ...
Thomas Johnson, Mia Venables, Babak Soleimani, Laurissa Havins, Annapoorna Kannan, Gregory Holt, Jonathan Cleaver, Adam E. Handel, Ava Easton, Defne Saatci, Lahiru Handunnetthi   +10 more
wiley   +1 more source

A rare case of tuberculous meningitis with pancreatitis

Medical Journal of Dr. D.Y. Patil University, 2016
Tuberculous meningitis (TBM) is the most common form of central nervous system manifestation of tuberculosis. However, tuberculous pancreatitis is rarely reported. We present an 8-year-old female child with TBM who had intractable vomiting that persisted
Drishti Chandru Tolani, Ira Shah
doaj   +1 more source

Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. [PDF]

, 2018
Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE.
Doty, Daniel J, Fujinami, Robert S, Grist, Jonathan J, Lane, Thomas E, Marro, Brett S, Skinner, Dominic D, Syage, Amber R, Worne, Colleen   +7 more
core   +1 more source

Mucosal‐Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 11, November 2025.
Mucosa‐associated invariant T (MAIT) cells are an evolutionarily conserved class of innate‐like T lymphocytes that rely on MR1 molecules to recognize microbial metabolites and play a central role in immune surveillance and inflammatory regulation.
Cheng Zhu, Qian Huai, Yishan Du, Xingyu Li, Fumin Zhang, Yongkang Zhang, Mengwei Wu, Ying Dai, Xiaolei Li, Hanren Dai, Hua Wang   +10 more
wiley   +1 more source

Central Nervous System Tuberculosis: A Case of Tuberculous Myelitis

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Tuberculous myelitis is rare in central nervous system (CNS) tuberculosis. Misdiagnosis initially may lead to poor outcomes; empirical antituberculosis treatment can improve symptoms. Early diagnosis via cerebrospinal fluid (CSF) and spinal MRI, plus timely treatment, is vital—clinical awareness needs enhancement.
Huan Nie, Xin Liu, Hui Song, Qingxia Liu, Linyuan Sun   +4 more
wiley   +1 more source

Chemotherapy of tuberculous meningitis with isoniazid plus rifampicin - interim findings in a trial in children [PDF]

, 1980
Seventy six cases of tuberculous meningitis admitted to the Institute of Child Health and Hospital for Children, Madras were treated with a regimen of rifampicin, isoniazid and streptomycin daily for two months, followed by streptomycin twice a week ...
Ramachandran, Padma
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