Results 241 to 250 of about 63,337 (330)

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

open access: yesGlia, Volume 73, Issue 10, Page 1928-1950, October 2025.
Main Points Multiple sclerosis involves chronic CNS inflammation and neurodegeneration. This review highlights glial cells as key drivers in progressive MS, focusing on lesion pathology, molecular dysfunction, and human‐relevant model systems. ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by ...
Volker Siffrin
wiley   +1 more source

Primary and secondary metastatic dissemination: multiple routes to cancer-related death. [PDF]

open access: yesMol Cancer
Sparrer D   +21 more
europepmc   +1 more source

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

open access: yesInternational Journal of Cancer, Volume 157, Issue 6, Page 1086-1093, 15 September 2025.
What's new? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk   +5 more
wiley   +1 more source

Meninges

open access: bronze, 2016
Douglas M. Templeton   +2 more
openalex   +2 more sources

Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice

open access: yesGlia, Volume 73, Issue 9, Page 1910-1924, September 2025.
Main Points Absence of DBN leads to larger spinal lesions, immune cell infiltration and attenuated astrocyte reactivity in the early phase post SCI. Absence of DBN leads to greater neurodegeneration, underscoring its importance in tissue repair.
Barbora Smejkalová   +12 more
wiley   +1 more source

Rhombencephalitis, a forgotten diagnosis in the post-partum period: a case report. [PDF]

open access: yesActa Neurochir (Wien)
Islamagič L   +5 more
europepmc   +1 more source

Primary Progressive Multiple Sclerosis: New Therapeutic Approaches

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 3, September 2025.
Primary progressive MS affects 10%–15% of MS patients, causing irreversible neurological impairment. Drugs like ocrelizumab show promise, while high‐dose biotin, simvastatin, and coenzyme Q10 are under investigation. Gene therapy and stem cell treatments also show potential.
Morteza Rajabi   +8 more
wiley   +1 more source

The meninges: new therapeutic targets for multiple sclerosis.

open access: yesTranslational research : the journal of laboratory and clinical medicine, 2015
Abigail E. Russi, Melissa A Brown
semanticscholar   +1 more source

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