Results 141 to 150 of about 142,166 (291)

Feasibility and safety of awake craniotomy in adult patients with drug‐resistant focal epilepsy

Epilepsia, EarlyView.
Abstract Objective Although awake craniotomy can guide functional brain mapping and resection, its feasibility and safety have been poorly studied in large series of patients with drug‐resistant focal epilepsy surgery. Methods We conducted an observational, retrospective, single‐center cohort study of 588 consecutive awake craniotomies (2010–2024 ...
Marc Zanello, Gonzague De France, Angela Elia, Marco Demasi, Cristina Filipescu, Elisabeth Landre, Alessandro Moiraghi, Bénédicte Trancart, Maimiti Seneca, Agathe Guibert, Fabrice Chretien, Alexandre Roux, Johan Pallud   +12 more
wiley   +1 more source

Merlin immunohistochemistry is a reliable surrogate marker for NF2 gene alterations in meningioma

Histopathology, EarlyView.
This study found that complete loss of Merlin immunostaining could serve as a reliable surrogate marker for NF2 gene alterations in low‐grade meningioma. We also introduce some pitfalls in the interpretation of its staining pattern. Aims Molecular characterization as well as histologic grading has proven useful in predicting the biological behaviour of
Mayu Kashiwagi‐Hakozaki, Masako Ikemura, Satoru Miyawaki, Yu Teranishi, Atsushi Okano, Nobuhito Saito, Tetsuo Ushiku   +6 more
wiley   +1 more source

Exploring the genetic correlation and causal relationships between breast cancer and meningioma using bidirectional Mendelian randomization

Scientific Reports
Previous studies have indicated a significantly higher prevalence of breast cancer (BC) among female patients with meningioma compared to the general female population.
Lu Ding, Bo Chen, Zhou Zhou, Zhaojun Mei, Kan Cao, Xinyu Lu, Wei Chen   +6 more
doaj   +1 more source

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade.

JCO Precision Oncology, 2018
Meningiomas are the most common primary tumor of the central nervous system, with ~28,000 new diagnoses annually in the United States1. Currently, there are no approved systemic therapies for meningiomas that recur following local treatment: chemotherapy
I. Dunn, Z. Du, M. Touat, M. Sisti, P. Wen, R. Umeton, A. Dubuc, M. Ducar, P. Canoll, E. Severson, J. Elvin, S. Ramkissoon, Jia-Ren Lin, Lais Cabrera, B. Acevedo, P. Sorger, K. Ligon, S. Santagata, D. Reardon   +18 more
semanticscholar   +1 more source

Optic Chiasm and Bilateral Optic Nerve Oligodendroglioma in A 29‐Month‐Old German Shepherd

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To report the first documented case of high‐grade optic chiasm and nerve oligodendroglioma in a young dog and contribute to the comparative study of gliomas in humans and canines. Animal Studied A 29‐month‐old male intact German Shepherd.
Vienna M. Lunking, Rajdeep Multani, Devin Fussell, LaTisha N. Knight, Erin Keenihan, Danielle M. Meritet, Abigail R. Armwood, Annie Oh   +7 more
wiley   +1 more source

Medical management of meningioma in the era of precision medicine.

Neurosurgical Focus, 2018
Surgery is curative for most meningiomas, but a minority of these tumors recur and progress after resection. Initial trials of medical therapies for meningioma utilized nonspecific cytotoxic chemotherapies. The presence of hormone receptors on meningioma
Saksham Gupta, W. Bi, I. Dunn
semanticscholar   +1 more source

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations

International Journal of Cancer, Volume 157, Issue 12, Page 2532-2543, 15 December 2025.
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang, Bryndis Yngvadottir, Avgi Andreou, Yasemin Cole, Emma R. Woodward, James Whitworth, Eamonn R. Maher   +6 more
wiley   +1 more source

Trends in intracranial meningioma incidence in the United States, 2004‐2015

Cancer Medicine, 2019
Background Meningioma incidence was reported to have risen substantially in the United States during the first decade of the 21st century. There are few reports about subsequent incidence trends.
Dong‐Dong Lin, Jia‐Liang Lin, Xiang‐Yang Deng, Wei Li, Dan‐Dong Li, Bo Yin, Jian Lin, Nu Zhang, Han‐Song Sheng   +8 more
doaj   +1 more source

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Parkinson's disease (PD) and glioma are neurological disorders with distinct and even opposing mechanisms: α‐synuclein deposition and neuronal loss in PD versus glial cell malignancy in glioma. Despite these differences, their contrasting pathologies highlight multiple therapeutic targets.
Tianli Pan, Lin Yuan, Ruoyang Zhao, Liting Lu, Yinghao Zhi, Yuying Li, Min Wu, Yongye Huang   +7 more
wiley   +1 more source

Organic Psychosis due to Lung Cancer Metastasis Accompanied by Severe Psychiatric Symptoms Treated With Blonanserin Transdermal Patch: A Case Report and Literature Review

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
Blonanserin transdermal patch may be effective for organic psychosis associated with brain metastasis. Because it can be used in cases where oral medication is difficult and has relatively few side effects, such as hypotension and extrapyramidal symptoms, it may be a helpful option for oncologists and liaison psychiatrists.
Junji Yamaguchi, Ryoichi Sadahiro, Saho Wada, Eri Nishikawa, Tatsuto Terada, Rika Nakahara, Hiromichi Matsuoka   +6 more
wiley   +1 more source