Results 1 to 10 of about 1,314,096 (303)
mBio, 2021 The impact of serogroup B meningococcal (MenB) vaccines on carriage is not completely understood. Using whole-genome sequencing data, we assessed the diversity and distribution of MenB vaccine antigens (particularly FHbp) among 1,514 meningococcal ...
Henju Marjuki +15 more
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mSphere, 2022 Predictions of vaccine efficacy against Neisseria meningitidis serogroup B (NmB) disease are hindered by antigenic variability, limiting the representativeness of individual NmB isolates.
Alessandro Muzzi +8 more
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Infectious Diseases and Therapy, 2023 Introduction The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced the number of pneumococcal infections.
Weronika Puzia +9 more
doaj +1 more source
Frontiers in Microbiology, 2022 In January and February 2015, Neisseria meningitidis serogroup B (NmB) outbreaks occurred at two universities in the United States, and mass vaccination campaigns using MenB vaccines were initiated as part of a public health response.
Melissa J. Whaley +19 more
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Bacterial meningitis in Africa
Frontiers in Neurology, 2023 Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region, country, pathogen, and age group; being a life-threatening disease with a high case fatality rate and long-term complications in low-income countries. Africa has the most significant prevalence of bacterial meningitis illness, and the outbreaks typically ...
Tatiana Barichello +16 more
openaire +4 more sources
Genomic characterization of Haemophilus influenzae: a focus on the capsule locus
BMC Genomics, 2019 Background Haemophilus influenzae (Hi) can cause invasive diseases such as meningitis, pneumonia, or sepsis. Typeable Hi includes six serotypes (a through f), each expressing a unique capsular polysaccharide.
Caelin C. Potts +11 more
doaj +1 more source
Role of Cerebrospinal Fluid Lactate and C-Reactive Protein in Differential Diagnosis of Meningitis in Adults [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Differentiating various types of meningitis is still a challenge as yield of microbiological tests are generally low in these disorders. Aim: To find out the role of Cerebrospinal Fluid (CSF) lactate and CSF C-reactive Protein (CRP) for the
Pediakkal M Jabir +2 more
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Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children [PDF]
, 2014 Extracellular heat shock protein 72 (Hsp72) is an endogenous danger signal and potential biomarker for critical illness in children. We hypothesized that elevated levels of extracellular Hsp72 in the cerebrospinal fluid (CSF) of children with suspected ...
Kernie, Steven G. +5 more
core +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
, 2017 In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
BMC Infectious Diseases, 2018 Background Neisseria meningitidis serogroup A disease in Burkina Faso has greatly decreased following introduction of a meningococcal A conjugate vaccine in 2010, yet other serogroups continue to pose a risk of life-threatening disease. Capsule switching
Adam C. Retchless +12 more
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