Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies. [PDF]
Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology.
Busscher, Henk J.+16 more
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Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis [PDF]
Background: Following the association of Cronobacter spp. to several publicized fatal outbreaks in neonatal intensive care units of meningitis and necrotising enterocolitis, the World Health Organization (WHO) in 2004 requested the establishment of a ...
Dickins, B, Forsythe, SJ, Jolley, KA
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Background: Historically, the major cause of meningococcal epidemics in the meningitis belt of sub-Saharan Africa has been Neisseria meningitidis serogroup A (NmA), but the incidence has been substantially reduced since the introduction of a serogroup A ...
Nadav Topaz+13 more
doaj +1 more source
The Role of Lactate Dehydrogenase in Differentiating Between Bacterial and Non -Bacterial Meningitis in children Under Five Years in Ramadi Maternity and Children Hospital [PDF]
The present study was designed to find out the usefulness of lactate dehydrogenase (LDH) level in cerebrospinal fluid (CSF) in differentiating bacterial from non-bacterial meningitis in children below 5 year of age .
Adnan M Jasim+2 more
doaj +1 more source
Effect of case management on neonatal mortality due to sepsis and pneumonia. [PDF]
BACKGROUND: Each year almost one million newborns die from infections, mostly in low-income countries. Timely case management would save many lives but the relative mortality effect of varying strategies is unknown.
Bhutta, Zulfiqar A+7 more
core +1 more source
The human pathogens Neisseria gonorrhoeae and Neisseria meningitidis share high genome identity. Retrospective analysis of surveillance data from New Zealand indicates the potential cross-protective effect of outer membrane vesicle (OMV) meningococcal ...
Henju Marjuki+5 more
doaj +1 more source
Spontaneous gram-negative bacillary meningitis in adult patients : characteristics and outcome [PDF]
Background: Spontaneous meningitis caused by gram-negative bacilli in adult patients is uncommon and poorly characterized. Our objective is to describe and compare the characteristics and the outcome of adult patients with spontaneous gram-negative ...
Benito, Natividad+6 more
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Prediction of bacterial meningitis based on cerebrospinal fluid pleocytosis in children
Children with cerebrospinal fluid pleocytosis are frequently treated with parenteral antibiotics, but only a few have bacterial meningitis. Although some clinical prediction rules, such as bacterial meningitis score, are of well-known value, the ...
Sofia Águeda, Teresa Campos, Ana Maia
doaj +3 more sources
Aseptic meningitis in a patient taking etanercept for rheumatoid arthritis: a case report [PDF]
Background \ud We report a case of a 53 year old lady recently commenced on etanercept, an anti-TNF (tumour necrosis factor) therapy for rheumatoid arthritis presenting with \ud confusion, pyrexia and an erythematous rash. \ud \ud Case presentation \ud
AP Cairns+13 more
core +4 more sources
Escherichia coli K1 RS218 Interacts with Human Brain Microvascular Endothelial Cells via Type 1 Fimbria Bacteria in the Fimbriated State [PDF]
Escherichia coli K1 is a major gram-negative organism causing neonatal meningitis. E. coli K1 binding to and invasion of human brain microvascular endothelial cells (HBMEC) are a prerequisite for E.
Cai, M.+7 more
core +2 more sources