Results 61 to 70 of about 1,314,096 (303)

Risk Factors and Comorbidity in Patients with Bacterial Meningitis

Acta Medica Bulgarica, 2023
Introduction. Bacterial meningitis is a severe disease with high mortality and frequent residual neurological sequelae. It is associated with multiple risk factors.
Argirova P., Kalchev Y., Murdjeva M., Stoycheva M.   +3 more
doaj   +1 more source

Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]

, 2017
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann, Dubberke, Erik, Franklin, Alexander, Lainhart, William, O\u27Halloran, Jane A, Powderly, William   +5 more
core   +2 more sources

Community-acquired Bacterial Meningitis in Adults With Cerebrospinal Fluid Leakage

Clinical Infectious Diseases, 2019
Background Cerebrospinal fluid (CSF) leakage is a risk factor for developing bacterial meningitis. Methods We analyzed episodes of community-acquired bacterial meningitis associated with CSF leakage from a prospective nationwide cohort study. Results CSF
Liora Ter Horst, M. Brouwer, A. van der Ende, D. van de Beek   +3 more
semanticscholar   +1 more source

Succinate Dehydrogenase Subunit A (SDHA) Mediated Microglia Extracellular Traps Formation Participating in Cerebral Ischemic Reperfusion Injury

Advanced Science, EarlyView.
This study investigates the mechanism of succinate dehydrogenase (SDH)‐mediated succinate oxidation in microglia extracellular traps (MiETs) formation and neuronal injury after cerebra I/R injury. Dimethyl malonate (DMM), a competitive SDH inhibitor, could reduce MiETosis by inhibiting succinate oxidation and mtROS production during reperfusion ...
Lili Zhao, Tao Li, Meijuan Dang, Ye Li, Jialiang Lu, Ziwei Lu, Zhiyang Chen, Qiao Huang, Yujie Chen, Yang Yang, Yuxuan Feng, Xiaoya Wang, Yating Jian, Heying Wang, Yingying Guo, Lei Zhang, Yu Jiang, Songhua Fan, Shengxi Wu, Hong Fan, Fang Kuang, Guilian Zhang   +21 more
wiley   +1 more source

Serum procalcitonin in viral and bacterial meningitis

Journal of Global Infectious Diseases, 2011
Background: In children with meningitis, there is a difficulty to verify the etiology as viral or bacterial. Therefore, intensive research has been carried out to find new and rapid diagnostic methods for differentiating bacterial from viral meningitis ...
Usama M Alkholi, Nermin Abd Al-monem, Ayman A Abd El-Azim, Mohamed H Sultan   +3 more
doaj   +1 more source

Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

Nature Communications, 2019
Bacterial mutations predisposing pneumococcus to causing meningitis, a more severe form of invasive pneumococcal disease (IPD), are largely unknown.
Yuan Li, B. Metcalf, S. Chochua, Zhongya Li, Hollis Walker, T. Tran, P. Hawkins, R. Gierke, T. Pilishvili, L. McGee, B. Beall   +10 more
semanticscholar   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

HUBUNGAN ANTARA TINGKAT KESADARAN DENGAN ANGKA KEMATIAN PADA PENDERITA MENINGITIS BAKTERI AKUT DI RSU HAJI SURABAYA PERIODE JANUARI 2006 ­DESEMBER 2009 [PDF]

, 2010
Background: Acute bacterial meningitis is one disease of causing a high level of mortality and morbidity rate, in Indonesia. Objective: To identify the relationship between consciousness level and mortality rate on patients of acute bacterial ...
ANITA, NIA
core  

Mathematical Modelling of Bacterial Meningitis Transmission Dynamics with Control Measures

Comput. Math. Methods Medicine, 2018
Vaccination and treatment are the most effective ways of controlling the transmission of most infectious diseases. While vaccination helps susceptible individuals to build either a long-term immunity or short-term immunity, treatment reduces the number ...
Joshua Kiddy K. Asamoah, F. Nyabadza, Baba Seidu, M. Chand, H. Dutta   +4 more
semanticscholar   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source