Results 61 to 70 of about 1,352,938 (323)

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Utility of cerebrospinal fluid cortisol level in acute bacterial meningitis

Annals of Indian Academy of Neurology, 2015
Background: Meningitis remains a serious clinical problem in developing as well as developed countries. Delay in diagnosis and treatment results in significant morbidity and mortality.
Anish Mehta, Rohan R Mahale, Uchil Sudhir, Mahendra Javali, Rangasetty Srinivasa   +4 more
doaj   +1 more source

Genomic dissection of the 1994 Cronobacter sakazakii outbreak in a French neonatal intensive care unit [PDF]

, 2015
Background: Cronobacter sakazakii is a member of the genus Cronobacter that has frequently been isolated from powdered infant formula (PIF) and linked with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
Dickins, B, Farbos, A, Forsythe, S, Masood, N, McNally, A, Moore, K, Paszkiewicz, K   +6 more
core   +2 more sources

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Risk Factors and Comorbidity in Patients with Bacterial Meningitis

Acta Medica Bulgarica, 2023
Introduction. Bacterial meningitis is a severe disease with high mortality and frequent residual neurological sequelae. It is associated with multiple risk factors.
Argirova P., Kalchev Y., Murdjeva M., Stoycheva M.   +3 more
doaj   +1 more source

HUBUNGAN ANTARA TINGKAT KESADARAN DENGAN ANGKA KEMATIAN PADA PENDERITA MENINGITIS BAKTERI AKUT DI RSU HAJI SURABAYA PERIODE JANUARI 2006 ­DESEMBER 2009 [PDF]

, 2010
Background: Acute bacterial meningitis is one disease of causing a high level of mortality and morbidity rate, in Indonesia. Objective: To identify the relationship between consciousness level and mortality rate on patients of acute bacterial ...
ANITA, NIA
core  

Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]

, 2011
BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach, Brian Greenwood, Daniel Ansong, David Schellenberg, Jahit Sacarlal, Jennifer Evans, Johan Vekemans, Kevin Marsh, Kwaku Asante, Mary J Hamel, Nahya Salim, null null, Patricia Njuguna, Philip Bejon, Portia Kamthunzi, Samwel Gesase, Solange Soulanoudjingar, Walter Otieno, William Kabore   +18 more
core   +4 more sources

Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis

Nature Communications, 2019
Bacterial mutations predisposing pneumococcus to causing meningitis, a more severe form of invasive pneumococcal disease (IPD), are largely unknown.
Yuan Li, B. Metcalf, S. Chochua, Zhongya Li, Hollis Walker, T. Tran, P. Hawkins, R. Gierke, T. Pilishvili, L. McGee, B. Beall   +10 more
semanticscholar   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

A Diagnostic Formula for Discrimination of Tuberculous and Bacterial Meningitis Using Clinical and Laboratory Features

Frontiers in Cellular and Infection Microbiology, 2020
Background: The discrimination of tuberculous meningitis and bacterial meningitis remains difficult at present, even with the introduction of advanced diagnostic tools.
Yun Yang, Xin-Hui Qu, Kun-Nan Zhang, Xiao-Mu Wu, Xin-Rong Wang, An Wen, Ling-Juan Li   +6 more
doaj   +1 more source