Results 51 to 60 of about 19,093 (217)

The Epidemiology of Meningitis among Adults in a South African Province with a High HIV Prevalence, 2009-2012. [PDF]

PLoS ONE, 2016
INTRODUCTION:Meningitis is a major cause of mortality in southern Africa. We aimed to describe the aetiologies and frequencies of laboratory-confirmed fungal and bacterial meningitis among adults in a South African province with an 11% HIV prevalence ...
Erika Britz, Olga Perovic, Claire von Mollendorf, Anne von Gottberg, Samantha Iyaloo, Vanessa Quan, Verushka Chetty, Charlotte Sriruttan, Nazir A Ismail, Ananta Nanoo, Alfred Musekiwa, Carl Reddy, Karien Viljoen, Cheryl Cohen, Nelesh P Govender   +14 more
doaj   +1 more source

Trends in Meningitis Burden and Projections to 2040: A Secondary Analysis of the Global Burden of Disease Study 2023

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Meningitis remains a global health challenge, characterized by substantial regional and etiologic disparities. This study aimed to analyze recent trends, forecast future burden, and examine the influence of development status on meningitis outcomes.
Mehdi Azizmohammad Looha, Ali Saberi Shahrbabaki, Fatemeh Masaebi, Mahmoud Zamani, Farid Zayeri   +4 more
wiley   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, Volume 13, Issue 17, 23 March 2026.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Performance of cryptococcal antigen lateral flow assay in serum, cerebrospinal fluid, whole blood, and urine in HIV-infected patients with culture-proven cryptococcal meningitis admitted at a Brazilian referral center

Revista do Instituto de Medicina Tropical de São Paulo, 2018
Cryptococcal meningitis is the most common cause of opportunistic meningitis in HIV-infected patients in Brazil and causes unacceptable high mortality rates.
José E. Vidal, Carolina Toniolo, Adriana Paulino, Arnaldo L. Colombo, Marilena dos Anjos Martins, Cristina da Silva Meira, Renata Guise Soares Azevedo, Vera Lucia Pereira-Chioccola, Hélio Rodrigues Gomes, Marcia dos Santos Lazera, Augusto C. Penalva de Oliveira, David R. Boulware   +11 more
doaj   +1 more source

Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]

, 2018
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R, Lee, Keunsook, Mukaremera, Liliane, Nielsen, Kirsten, Wagener, Jeanette, Wiesner, D. L.   +5 more
core   +1 more source

Experiences of HIV–Related Stigma and Mental Illness Among HIV–Associated Meningitis Patients in Rural Uganda

Brain and Behavior, Volume 16, Issue 2, February 2026.
Meningitis patients living with HIV often struggle with medication adherence and seeking HIV care due to the lack of education, support, and HIV‐related stigma, which can contribute to the development of mental health conditions in some individuals.
Abigail Link, Sarah Iribarren, Paul Bohjanen, Mark Okwir, David Meya, Betty Nabongo, Danuta Kasprzyk   +6 more
wiley   +1 more source

Meningoencephalitis in a Young Immunocompetent Patient

Journal of Investigative Medicine High Impact Case Reports
Cryptococcal meningitis is mainly seen in immunocompromised patients, but in recent years, there has been an increase in cases involving patients with no known immunodeficiencies. These patients have symptomatic presentations that range from indolent and
Michael Ke MD, Neeki Ettefagh, Ahmet Semih Topbas MD, Mehdi Kazemi MD   +3 more
doaj   +1 more source

Molecular diagnosis of cryptococcal meningitis in cerebrospinal fluid: comparison of primer sets for Cryptococcus neoformans and Cryptococcus gattii species complex

Brazilian Journal of Infectious Diseases, 2015
Aim: This study evaluated the use of polymerase chain reaction for cryptococcal meningitis diagnosis in clinical samples. Materials and methods: The sensitivity and specificity of the methodology were evaluated using eight Cryptococcus neoformans/C ...
Marilena dos Anjos Martins, Kate Bastos Santos Brighente, Terezinha Aparecida de Matos, Jose Ernesto Vidal, Daise Damaris Carnietto de Hipólito, Vera Lucia Pereira-Chioccola   +5 more
doaj   +1 more source

Management of long-term cryptococcal meningitis neoformans in a surviving patient: A case report

Frontiers in Medicine, 2022
Cryptococcal meningitis is a common fungal infection of the central nervous system with high mortality and disability rates. A prominent clinical manifestation is persistent and severe cranial hypertension, which is one of the most critical outcome ...
Shijun Hu, Tao Liu, Shixiong Huang, Hui Liang   +3 more
doaj   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source