Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases. [PDF]
BACKGROUND: The presentation and causes of adult meningitis in South Africa have changed substantially as a result of HIV. Knowledge of aetiology and laboratory findings in patients presenting with meningitis are important in guiding management.
Crede Tom +25 more
core +1 more source
Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients. [PDF]
BACKGROUND: As important regulators of the immune system, the human Fcγ receptors (FcγRs) have been demonstrated to play important roles in the pathogenesis of various infectious diseases.
Xiu-Ping Hu +7 more
doaj +1 more source
Cryptococcal meningitis is a life-threatening disease. Headache, vomiting, cranial nerve symptoms and mental changes are the most common symptoms, but as many as 15% may have no symptoms referable to the CNS. For chemotherapy four drugs are available: namely amphotericin B, 5-fluorocytosine, miconazole and ketoconazole.
R, Biniek, F, Hilgenstock, V, Schuchardt
openaire +3 more sources
Cryptococcal meningitis: improving access to essential antifungal medicines in resource-poor countries [PDF]
Cryptococcal meningitis is the leading cause of adult meningitis in sub-Saharan Africa, and contributes up to 20% of AIDS-related mortality in low-income and middle-income countries every year.
Chiller, Tom +8 more
core +1 more source
Prevalence of Cryptococcal meningitis among Immunocompetent and immunocompromised Individuals in Bellary, South India – a Prospective Study [PDF]
Background and objectives: Cryptococcal meningitis is now the leading cause of community acquired meningitis. It is generally thought to be associated with AIDS individuals.
Kanchan Mahale +4 more
doaj
Background The clinical profiles and outcomes of cryptococcal meningitis have been shown to vary depending on the underlying condition. The aim of this study was to investigate clinical characteristics and outcomes in patients with and without type II ...
Hang Li +15 more
doaj +1 more source
Cryptococcal meningitis: A neglected NTD? [PDF]
Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation.
Molloy, S.F. +22 more
openaire +7 more sources
Low Diversity Cryptococcus neoformans Variety grubii Multilocus Sequence Types from Thailand Are Consistent with an Ancestral African Origin [PDF]
The global burden of HIV-associated cryptococcal meningitis is estimated at nearly one million cases per year, causing up to a third of all AIDS-related deaths.
Fisher, M.D. +46 more
core +1 more source
Purpose: Shunt procedures used to treat cryptococcal meningitis complicated with hydrocephalus and/or increased intracranial pressure (IICP) could result in cerebrospinal fluid (CSF) overdrainage, thereby presenting therapeutic challenges.
Chih-Wei Hung +13 more
doaj +1 more source
Capsule independent uptake of the fungal pathogen Cryptococcus neoformans into brain microvascular endothelial cells. [PDF]
Cryptococcosis is a life-threatening fungal disease with a high rate of mortality among HIV/AIDS patients across the world. The ability to penetrate the blood-brain barrier (BBB) is central to the pathogenesis of cryptococcosis, but the way in which this
May, Robin C +10 more
core +1 more source

