Results 31 to 40 of about 67,978 (217)

Low CD4 count plus coma predicts cryptococcal meningitis in Tanzania

BMC Infectious Diseases, 2007
Background Largely due to the lack of diagnostic reagents, the prevalence and clinical presentation of cryptococcal meningitis in Tanzania is poorly understood. This in turn is limiting the impact of increased fluconazole availability.
Mueller Andreas, Swai Ndealilia S, Mchele John PD, Maro Venance P, Hawkins Alexander T, Kisenge Peter R, Houpt Eric R   +6 more
doaj   +1 more source

Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients. [PDF]

PLoS ONE, 2012
BACKGROUND: As important regulators of the immune system, the human Fcγ receptors (FcγRs) have been demonstrated to play important roles in the pathogenesis of various infectious diseases.
Xiu-Ping Hu, Ji-Qin Wu, Li-Ping Zhu, Xuan Wang, Bin Xu, Rui-Ying Wang, Xue-Ting Ou, Xin-Hua Weng   +7 more
doaj   +1 more source

Another case of cryptococcal meningitis in a person without HIV who injects drugs: A possible risk factor in need of further investigation

Medical Mycology Case Reports, 2022
Cryptococcal meningitis is a fungal central nervous infection typically occurring in patients with severe immunocompromise. We present a case of cryptococcal meningitis occurring in a patient with active injection drug use (IDU) but no immunocompromising
L. Madeline McCrary, Ryan Paulus, J. Kyle Melvin, John Perfect, Becky L. White   +4 more
doaj   +1 more source

AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo, Síle F. Molloy, Changalucha, John M., Molefi, Mooketsi, Molloy, Síle F, Meintjes, Graeme, Molloy, Síle F., Goldberg, Drew W, John R. Perfect, Drew W. Goldberg, Kalluvya, Samuel, Cainelli, Francesca, Letang, Emili, Ndhlovu, Chiratidzo E, Perfect, John R, Ndhlovu, Chiratidzo E., Bisson, Gregory P., Miriam Haverkamp, Burton, Rosie, Rosie Burton, Tariro Makadzange, Harrison, Thomas S, Francesca Cainelli, Hope, William, Haverkamp, Miriam, Chiratidzo E. Ndhlovu, Harrison, Thomas S., Jarvis, Joseph N., Chofle, Awilly A, William Hope, Jarvis, Joseph N, Changalucha, John M, Fenner, Lukas, Perfect, John R., Makadzange, Tariro, Joseph N. Jarvis, Tshepo Leeme, Mooketsi Molefi, Nametso Lekwape, Lekwape, Nametso, John M. Changalucha, Emili Letang, Goldberg, Drew W., Lukas Fenner, Bisson, Gregory P, Awilly A. Chofle, Samuel Kalluvya, Thomas S. Harrison, Graeme Meintjes, Chofle, Awilly A., Gregory P. Bisson   +50 more
core   +2 more sources

Cryptococcal meningitis [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1986
Cryptococcal meningitis is a life-threatening disease. Headache, vomiting, cranial nerve symptoms and mental changes are the most common symptoms, but as many as 15% may have no symptoms referable to the CNS. For chemotherapy four drugs are available: namely amphotericin B, 5-fluorocytosine, miconazole and ketoconazole.
R, Biniek, F, Hilgenstock, V, Schuchardt
openaire   +3 more sources

A case report of a brain herniation secondary to cryptococcal meningitis with elevated intracranial pressure in a patient with Human Immunodeficiency Virus/Acquired immunodeficiency syndrome (HIV/AIDS)

IDCases, 2022
Background: Cryptococcal meningitis is a major opportunistic infection in individuals with HIV. The worldwide annual incidence is estimated to be approximately one million cases per year, with the most significant burden in sub-Saharan Africa.
Nehemias Guevara, Abdulrasheed Akande, Mailing Flores Chang, Jane Atallah, Carol Epstein   +4 more
doaj   +1 more source

Prevalence of Cryptococcal meningitis among Immunocompetent and immunocompromised Individuals in Bellary, South India – a Prospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2012
Background and objectives: Cryptococcal meningitis is now the leading cause of community acquired meningitis. It is generally thought to be associated with AIDS individuals.
Kanchan Mahale, Satish Patil, Ravikumar, Nagabhushan, Ramanath Mahale   +4 more
doaj  

Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases. [PDF]

, 2010
BACKGROUND: The presentation and causes of adult meningitis in South Africa have changed substantially as a result of HIV. Knowledge of aetiology and laboratory findings in patients presenting with meningitis are important in guiding management.
Crede Tom, Williams, A, Thomas S Harrison, Meintjes, Graeme, Brown Yolande, Harrison Thomas S, Jarvis, Joseph, Yolande Brown, Tom Crede, Joseph N Jarvis, Jarvis, JN, Meintjes Graeme, Harrison, Thomas, Crede, Tom, Anthony Williams, Jarvis Joseph N, Harrison, Thomas S, Brown, Y, Brown, Yolande, Harrison, TS, Crede, T, Williams, Anthony, Graeme Meintjes, Williams Anthony, Meintjes, G, Jarvis, Joseph N   +25 more
core   +2 more sources

The clinical profiles and outcomes of HIV-negative cryptococcal meningitis patients in type II diabetes mellitus

BMC Infectious Diseases, 2021
Background The clinical profiles and outcomes of cryptococcal meningitis have been shown to vary depending on the underlying condition. The aim of this study was to investigate clinical characteristics and outcomes in patients with and without type II ...
Hang Li, Xiaojing Li, Lei Zhang, Wenjie Fang, Keming Zhang, Amir Arastehfar, Macit Ilkit, Dongying Hu, Xianzhen Chen, Huiwei Wang, Liyan Ling, Jianjun Lin, Bin Xu, Wanqing Liao, Weihua Pan, Qilong Zhang   +15 more
doaj   +1 more source

Cryptococcal meningitis: A neglected NTD? [PDF]

PLOS Neglected Tropical Diseases, 2017
Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation.
Molloy, S.F., Chiller, T., Greene, G.S., Burry, J., Govender, N.P., Kanyama, C., Mfinanga, S., Lesikari, S., Mapoure, Y.N., Kouanfack, C., Sini, V., Temfack, E., Boulware, D.R., Dromer, F., Denning, D.W., Day, J., Stone, N.R.H., Bicanic, T., Jarvis, J.N., Lortholary, O., Harrison, T.S., Jaffar, S., Loyse, A.   +22 more
openaire   +7 more sources