Results 11 to 20 of about 19,093 (217)

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. [PDF]

Lancet Infectious Diseases, The, 2017
BACKGROUND: Cryptococcus is the most common cause of meningitis in adults living with HIV in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies and to determine treatment needs, and we aimed to provide an updated ...
Angela Loyse, Avila, Baldassarre, Bansi, Benjamin J Park, Butler, Castelnuovo, Castelnuovo, Castelnuovo, David R Boulware, David W Denning, Durski, French, Gaskell, Govender, Jarvis, Jarvis, Jarvis, Jarvis, Jarvis, Jongwutiwes, Joseph N Jarvis, Kendi, Lahuerta, Lawn, Lawn, Lessells, Letang, Letang, Liechty, Lortholary, Lozano, Masur, Mayanja-Kizza, McKenney, McMahon, Meya, Mfinanga, Mfinanga, Mirza, Mocroft, Moore, Mwaba, Nelesh P Govender, Park, Parkes-Ratanshi, Pongsai, Pyrgos, Rachel M Smith, Radha Rajasingham, Rajasingham, Rajasingham, Rajasingham, Resch, Rothe, Sanne, Siddiqi, Siedner, Tom M Chiller, Uy, Vidal, Wall   +61 more
core   +5 more sources

Vision loss in an AIDS patient with cryptococcal meningitis

Medical Mycology Case Reports, 2019
Cryptococcal meningitis is considered one of the AIDS-defining illness and has been reported to be associated with neurological sequels. However, acute vision loss as presenting complaint is rare in Cryptococcal meningitis.
Wafa Ali Aldhaleei, Akshaya Srikanth Bhagavathula, Ameera Alhajeri   +2 more
doaj   +1 more source

Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing. [PDF]

, 2019
Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral ...
Beyene, T, Boulware, DR, Katende, A, Letang, E, Rajasingham, R, Wake, RM   +5 more
core   +1 more source

Cryptococcal Meningitis in HIV Patients from a Tertiary Care Centre in Northern India [PDF]

National Journal of Laboratory Medicine, 2019
Introduction: Cryptococcal meningitis, caused by Cryptococcus neoformans, an opportunistic fungal infection that affects immunocompromised Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) patients.
Shiwangi Sharma, Arvind Achra, Renu Kumari, Anuradha, Nandini Duggal   +4 more
doaj   +1 more source

Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]

, 2020
Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R, Lam, Woei C, Lodge, Jennifer K, Upadhya, Rajendra   +3 more
core   +2 more sources

Cognitive biases and knowledge deficits leading to delayed recognition of cryptococcal meningitis

IDCases, 2019
Cryptococcal meningitis is a potentially devastating infectious complication of immunosuppression best characterized in individuals with HIV. Early recognition of and appropriate antifungal therapy for cryptococcal meningitis has a profound effect on ...
M. Deming, A. Mark, V. Nyemba, E.L. Heil, R.M. Palmeiro, S.A. Schmalzle   +5 more
doaj   +1 more source

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. [PDF]

, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
Aller, Altamirano, Arechavala, Bicanic, Bicanic, Boeva, Chang, Chen, Dannaoui, DePristo, Drusano, Harrison, Li, Longley, Loyse, Martin, Mayanja-Kizza, McKenna, Molloy, Mondon, Neely, Nixon, Nussbaum, Saag, Sionov, Sionov, Stone, Stott, Stott, Sudan, Wiederhold, Witt   +31 more
core   +1 more source

High Cryptococcal Antigen Titers in Blood Are Predictive of Subclinical Cryptococcal Meningitis Among Human Immunodeficiency Virus-Infected Patients [PDF]

, 2017
Background High mortality rates among asymptomatic cryptococcal antigen (CrAg)–positive patients identified through CrAg screening, despite preemptive fluconazole treatment, may be due to undiagnosed cryptococcal meningitis.
Adeboye Adelekan, Charlotte Sriruttan, David C Spencer, Department of Health, South Africa, Desmet, Erika Britz, French, Govender, Ivy Rukasha, Jarvis, Jeremy S Nel, Joseph N Jarvis, Kapoor, Kempker, Kirkland, Kisenge, Letang, Longley, Mfinanga, Micol, Morawski, Nelesh P Govender, Pac, Petti, Pongsai, Rachel M Wake, Sello Mashamaite, Tanvier Omar, Thakur, Thomas S Harrison, Tom M Chiller, Wajanga, World Health Organization, World Health Organization, World Health Organization   +34 more
core   +1 more source

Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults. [PDF]

, 2018
We report 5 HIV-infected Ugandan adults with cryptococcal and tuberculous (TB) meningitis co-infection. All unmasked meningitis occurred within 5 weeks of starting HIV therapy.
Boulware, David R, Cresswell, Fiona V, Ellis, Jayne, Rhein, Joshua, Ssebambulidde, Kenneth   +4 more
core   +1 more source

Cryptococcal meningitis: A neglected NTD? [PDF]

PLOS Neglected Tropical Diseases, 2017
Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation.
Molloy, S.F., Chiller, T., Greene, G.S., Burry, J., Govender, N.P., Kanyama, C., Mfinanga, S., Lesikari, S., Mapoure, Y.N., Kouanfack, C., Sini, V., Temfack, E., Boulware, D.R., Dromer, F., Denning, D.W., Day, J., Stone, N.R.H., Bicanic, T., Jarvis, J.N., Lortholary, O., Harrison, T.S., Jaffar, S., Loyse, A.   +22 more
openaire   +7 more sources